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Authordc.contributor.authorBustos-Obregón, Eduardo 
Authordc.contributor.authorPoblete, Daniel 
Authordc.contributor.authorCatriao, Roberto 
Authordc.contributor.authordel Sol, Mariano 
Authordc.contributor.authorFernandes, Fábio Henrique 
Admission datedc.date.accessioned2019-03-15T16:06:02Z
Available datedc.date.available2019-03-15T16:06:02Z
Publication datedc.date.issued2013
Cita de ítemdc.identifier.citationInternational Journal of Morphology, Volumen 31, Issue 4, 2018, Pages 1251-1256
Identifierdc.identifier.issn07179367
Identifierdc.identifier.issn07179502
Identifierdc.identifier.other10.4067/S0717-95022013000400017
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/166098
Abstractdc.description.abstractWe evaluated the sperm parameters such as cauda epididymis weight, sperm count, sperm morphology and sperm DNA stability of adult CF-1 male mice treated daily (oral exposure) with the toxic sodium arsenite (As, 7.0 mg/kg/body weight); Melatonin (Me, 10.0 mg/kg/bw), Me (10.0 mg/kg/bw) plus As (7.0 mg/kg/bw) and Negative Control (NaCl 0.9%) to assess acute (8.3 days), chronic (33.2 days) and recovery of testicular damage (66.4 days). Arsenic decreases the number of sperm from chronic treatment (33.2 days) and this effect continued until 66.4 days of treatment. The toxic effect of As also altered the morphology of spermatozoa in all treatment periods when compared to the negative control group. However, Metalonin induced protective effects in periods of 33.2 and 66.4 days of treatment. Additionally, the stability of DNA was significantly affected by arsenic in all periods, but the chronic treatment (33.2 days) in the AsMe revealed increased stability compared to the group treated with ars
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceInternational Journal of Morphology
Keywordsdc.subjectArsenic
Keywordsdc.subjectDNA stability
Keywordsdc.subjectMelatonin
Keywordsdc.subjectMouse
Keywordsdc.subjectSperm
Títulodc.titleMelatonin protective role in mouse cauda epipidymal spermatozoa damage induced by sodium arsenite Rol protector de la melatonina en el daño de espermatozoides de cauda epididimaria en ratón producido por arsenito de sodio
Document typedc.typeArtículo de revista
dcterms.accessRightsdcterms.accessRightsAcceso Abierto
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile