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Author | dc.contributor.author | Assar, Rodrigo | |
Author | dc.contributor.author | Montecino, Martín A. | |
Author | dc.contributor.author | Maass Sepúlveda, Alejandro | |
Author | dc.contributor.author | Sherman, David J. | |
Admission date | dc.date.accessioned | 2019-03-15T16:06:42Z | |
Available date | dc.date.available | 2019-03-15T16:06:42Z | |
Publication date | dc.date.issued | 2014 | |
Cita de ítem | dc.identifier.citation | BioSystems, Volumen 121, | |
Identifier | dc.identifier.issn | 18728324 | |
Identifier | dc.identifier.issn | 03032647 | |
Identifier | dc.identifier.other | 10.1016/j.biosystems.2014.05.007 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/166189 | |
Abstract | dc.description.abstract | In order to describe the dynamic behavior of a complex biological system, it is useful to combine models integrating processes at different levels and with temporal dependencies. Such combinations are necessary for modeling acclimatization, a phenomenon where changes in environmental conditions can induce drastic changes in the behavior of a biological system. In this article we formalize the use of hybrid systems as a tool to model this kind of biological behavior. A modeling scheme called strong switches is proposed. It allows one to take into account both minor adjustments to the coefficients of a continuous model, and, more interestingly, large-scale changes to the structure of the model. We illustrate the proposed methodology with two applications: acclimatization in wine fermentation kinetics, and acclimatization of osteo-adipo differentiation system linking stimulus signals to bone mass. © 2014 Elsevier Ireland Ltd. | |
Lenguage | dc.language.iso | en | |
Publisher | dc.publisher | Elsevier Ireland Ltd | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | BioSystems | |
Keywords | dc.subject | Acclimatization | |
Keywords | dc.subject | Hybrid systems | |
Título | dc.title | Modeling acclimatization by hybrid systems: Condition changes alter biological system behavior models | |
Document type | dc.type | Artículo de revista | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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