Fecal microbiota transplantation in recurrent Clostridium difficile infection. Report of one case Trasplante de microbiota fecal en infección recurrente por Clostridium difficile. Experiencia local a partir de un caso clínico

Abstract

© 2015, Sociedad Medica de Santiago. All rights reserved. Fecal microbiota transplantation (FMT) has an incomparable efficacy to treat recurrent Clostridium difficile infection, with near 90% of success. We report a 57 years old woman who developed an antibiotic associated diarrhea with a positive polymerase chain reaction test for Clostridium Difficile toxin. She was successfully treated with Vancomycin trice but diarrhea recurred. Therefore a fecal microbiota transplant was performed using solid stools from a relative, diluted in saline and instilled in the distal ileon, with a good clinical response, without recurrence of diarrhea, during a 6-month follow-up.