The Effect of Human Growth Hormone, 17 α-methyl-17 β-hydroxyandrost-1,4-dien-3one and 1-methyl-⊿’-5 α-androsten-17 β-ol-3-on-17 β-acetate on the Net Protein Utilization of a 10% Casein Diet and on the Carcass Composition of the Rat L’effet de l’hormone de

Abstract

The effect of human growth hormone (HGH) and of two anabolic drugs: 17 α methyl-17 ²-hydroxyandrost-1,4-dien-3one (Dianabol) and 1-methyl- Delta'-5 α-androsten-17 β-ol-3-ou-17 㬒-acetate, on the effici ency (measured as Net Protein Utilization) of a 10% cascin diet is reported. The experiment was performed on 31 day-old rots which received the diet and a drug during 10 days. At the end of this period the rats were killed and their carcasses analyzed for water. protein and fat. The results show tbat the three drugs tested increase the efficiency (measured as Net Protein Utilization) of the casein diet. The percentage of protein in the carcass was inc reased above the control value in the three groups that received a drug. The fat content of the HGH treated rats was lower than that for the control animals; the groups that received a steroid show but little difference in this cooneetion with the control. A series of equations are used to interpret the possible effect i. e. anticataholic/an