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Author dc.contributor.author Chan, Edward
Author dc.contributor.author Anderson, Craig S.
Author dc.contributor.author Wang, Xia
Author dc.contributor.author Arima, Hisatomi
Author dc.contributor.author Saxena, Anubhav
Author dc.contributor.author Moullaali, Tom J.
Author dc.contributor.author Delcourt, Candice
Author dc.contributor.author Wu, Guojun
Author dc.contributor.author Wang, Jinchao
Author dc.contributor.author Chen, Guofang
Author dc.contributor.author Lavados Germain, Pablo Manuel
Author dc.contributor.author Stapf, Christian
Author dc.contributor.author Robinson, Thompson
Author dc.contributor.author Chalmers, John
Admission date dc.date.accessioned 2019-03-18T11:54:52Z
Available date dc.date.available 2019-03-18T11:54:52Z
Publication date dc.date.issued 2016
Cita de ítem dc.identifier.citation Cerebrovascular Diseases Extra, Volumen 6, Issue 3, 2018, Pages 71-75
Identifier dc.identifier.issn 16645456
Identifier dc.identifier.other 10.1159/000448897
Identifier dc.identifier.uri https://repositorio.uchile.cl/handle/2250/166854
Abstract dc.description.abstract © 2016 The Author(s). Background: Intraventricular hemorrhage (IVH) extension is common following acute intracerebral hemorrhage (ICH) and is associated with poor prognosis. Aim: To determine whether intensive blood pressure (BP)-lowering therapy reduces IVH growth. Methods: Pooled analyses of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials (INTERACT1 and INTERACT2) computed tomography (CT) substudies; multicenter, open, controlled, randomized trials of patients with acute spontaneous ICH and elevated systolic BP, randomly assigned to intensive (<140 mm Hg) or guideline-based (<180 mm Hg) BP management. Participants had blinded central analyses of baseline and 24-hour CT. Association of BP lowering to IVH growth was assessed in analysis of covariance. Results: There was no significant difference in adjusted mean IVH growth following intensive (n = 228) compared to guideline-recommended (n = 228) BP treatment (1.6 versus 2.2 ml, respectively; p = 0.56). Adjust
Lenguage dc.language.iso en
Publisher dc.publisher S. Karger AG
Type of license dc.rights Attribution-NonCommercial-NoDerivs 3.0 Chile
Link to License dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Source dc.source Cerebrovascular Diseases Extra
Keywords dc.subject Hypertension
Keywords dc.subject Intensive blood pressure lowering
Keywords dc.subject Intracerebral hemorrhage
Keywords dc.subject Intraventricular hemorrhage
Keywords dc.subject Stroke
Título dc.title Early Blood Pressure Lowering Does Not Reduce Growth of Intraventricular Hemorrhage following Acute Intracerebral Hemorrhage: Results of the INTERACT Studies
Document type dc.type Artículo de revista
dcterms.accessRights dcterms.accessRights Acceso Abierto
Cataloguer uchile.catalogador SCOPUS
Indexation uchile.index Artículo de publicación SCOPUS
uchile.cosecha uchile.cosecha SI
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