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Author | dc.contributor.author | Franco, Cavalla | |
Author | dc.contributor.author | Patricia, Hernández Rios | |
Author | dc.contributor.author | Timo, Sorsa | |
Author | dc.contributor.author | Claudia, Biguetti | |
Author | dc.contributor.author | Marcela, Hernández | |
Admission date | dc.date.accessioned | 2019-03-18T11:55:27Z | |
Available date | dc.date.available | 2019-03-18T11:55:27Z | |
Publication date | dc.date.issued | 2017 | |
Cita de ítem | dc.identifier.citation | International Journal of Molecular Sciences, Volumen 18, Issue 2, 2018, | |
Identifier | dc.identifier.issn | 14220067 | |
Identifier | dc.identifier.issn | 16616596 | |
Identifier | dc.identifier.other | 10.3390/ijms18020440 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/166950 | |
Abstract | dc.description.abstract | © 2017 by the authors; licensee MDPI, Basel, Switzerland. Periodontitis are infectious diseases characterized by immune-mediated destruction of periodontal supporting tissues and tooth loss. Matrix metalloproteinases (MMPs) are key proteases involved in destructive periodontal diseases. The study and interest in MMP has been fuelled by emerging evidence demonstrating the broad spectrum of molecules that can be cleaved by them and the myriad of biological processes that they can potentially regulate. The huge complexity of MMP functions within the ‘protease web’ is crucial for many physiologic and pathologic processes, including immunity, inflammation, bone resorption, and wound healing. Evidence points out that MMPs assemble in activation cascades and besides their classical extracellular matrix substrates, they cleave several signalling molecules—such as cytokines, chemokines, and growth factors, among others—regulating their biological functions and/or bioavailability during periodon | |
Lenguage | dc.language.iso | en | |
Publisher | dc.publisher | MDPI AG | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | International Journal of Molecular Sciences | |
Keywords | dc.subject | Chronic periodontitis | |
Keywords | dc.subject | MMPs | |
Keywords | dc.subject | Modulation | |
Keywords | dc.subject | Periodontal inflammation regulation | |
Título | dc.title | Matrix metalloproteinases as regulators of periodontal inflammation | |
Document type | dc.type | Artículo de revista | |
dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile