Does obesity in pregnancy related to fetal death due to placental insufficiency? Se relaciona la obesidad en el embarazo con muerte fetal por insuficiencia placentaria
Author
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Alfredo Ovalle, S.
Author
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Trinidad Barriga, M.
Author
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Elena Kakarieka, W.
Admission date
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2019-03-18T12:01:05Z
Available date
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2019-03-18T12:01:05Z
Publication date
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2017
Cita de ítem
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Revista Chilena de Obstetricia y Ginecologia, Volumen 82, Issue 6, 2018, Pages 614-620
Identifier
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07177526
Identifier
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0048766X
Identifier
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https://repositorio.uchile.cl/handle/2250/167331
Abstract
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We present 4 cases of fetal death in obese pregnant women with term pregnancies, with several placental findings suggesting placental insufficiency, that could be associated with obesity. According to recent evidence obesity could be associated with inadequate fetal growth and adverse outcomes especially at term pregnancies, through the decrease of mediators such as apelin, leptin, regulators of placental vascular tone and other regulators of angiogenesis altering placental function. We report a rarely described mechanism possibly related to obesity and unfavorable outcome of pregnancy.
Does obesity in pregnancy related to fetal death due to placental insufficiency? Se relaciona la obesidad en el embarazo con muerte fetal por insuficiencia placentaria