«Prognostic factors for survival of patients with osteosarcoma» «Factores pronósticos de sobrevida de pacientes con osteosarcoma»

Abstract

© 2016 Sociedad Chilena de Ortopedia y Traumatología. Objective: To identify prognostic factors of survival in patients with osteosarcoma, using a parametric survival model. Material and methods: A retrospective cohort study was carried out on 68 patients diagnosed with osteosarcoma and who were treated at Traumatology Institute from January 1 2002 to December 31 2012.In order to calculate the mean incidence of osteosarcoma, the population greater than or equal to 15 years old during the study period was considered as a denominator. The following were inclusion criteria: patients of either sex, age greater than or equal to 15 years, and positive biopsy for any kind of osteosarcoma.The following predictor variables were considered: sex, tumour site, lung metastasis, relapse, kind of osteosarcoma, histological grade, treatment, and percentage of tumour necrosis. Results: The mean incidence rate of osteosarcoma in the population studied was 0.98 cases per 1 million people per year. As a p