Catechol-mediated effects of harmaline on the action potential of rat atrial fibres
| Author | dc.contributor.author | Carpentier, | |
| Author | dc.contributor.author | Narvarte, | |
| Author | dc.contributor.author | Sanhueza, | |
| Admission date | dc.date.accessioned | 2019-03-18T12:02:16Z | |
| Available date | dc.date.available | 2019-03-18T12:02:16Z | |
| Publication date | dc.date.issued | 1977 | |
| Cita de ítem | dc.identifier.citation | Cardiovascular Research, Volumen 11, Issue 1, 2018, Pages 39-46 | |
| Identifier | dc.identifier.issn | 00086363 | |
| Identifier | dc.identifier.other | 10.1093/cvr/11.1.39 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/167473 | |
| Abstract | dc.description.abstract | Summary: The mechanism of the transient enhancement of the amplitude of the action potential (AAP) induced by harmaline (HME) was studied in rat atria. The results show that HME increases AAP through an enhancement of the slow component responsible for the last part of the upstroke, which overcomes an inhibitory action on the initial fast component. The stimulatory effect on the slow component is mediated through adrenergic beta receptors and normally masks an alpha-dependent depressant effect. | |
| Lenguage | dc.language.iso | en | |
| Publisher | dc.publisher | Oxford University Press | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Cardiovascular Research | |
| Keywords | dc.subject | Physiology | |
| Keywords | dc.subject | Cardiology and Cardiovascular Medicine | |
| Keywords | dc.subject | Physiology (medical) | |
| Título | dc.title | Catechol-mediated effects of harmaline on the action potential of rat atrial fibres | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile