Neurotoxins as Preclinical Models for Parkinson’s Disease
| Author | dc.contributor.author | Segura Aguilar, Juan | |
| Admission date | dc.date.accessioned | 2019-03-18T12:02:27Z | |
| Available date | dc.date.available | 2019-03-18T12:02:27Z | |
| Publication date | dc.date.issued | 2018 | |
| Cita de ítem | dc.identifier.citation | Neurotoxicity Research, Volumen 34, Issue 4, 2018, Pages 870-877 | |
| Identifier | dc.identifier.issn | 14763524 | |
| Identifier | dc.identifier.issn | 10298428 | |
| Identifier | dc.identifier.other | 10.1007/s12640-017-9856-0 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/167522 | |
| Abstract | dc.description.abstract | © 2018, Springer Science+Business Media, LLC, part of Springer Nature.Translational medicine is one of the major concerns in this century. While significant advances have been made with scientific knowledge, the translation of their promising results has not led to any new therapies. In Parkinson’s disease, a long list of clinical studies, based on preclinical models with exogenous neurotoxins, has failed. Therefore, the aim of this opinion paper is to open discussion about preclinical models for Parkinson’s disease based on neurotoxins. | |
| Lenguage | dc.language.iso | en | |
| Publisher | dc.publisher | Springer New York LLC | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Neurotoxicity Research | |
| Keywords | dc.subject | 6-Hydroxydopamine | |
| Keywords | dc.subject | Aminochrome | |
| Keywords | dc.subject | Clinical studies | |
| Keywords | dc.subject | Dopamine | |
| Keywords | dc.subject | MPTP | |
| Keywords | dc.subject | Neurodegeneration | |
| Keywords | dc.subject | Neurotoxins | |
| Keywords | dc.subject | Parkinson’s disease | |
| Keywords | dc.subject | Preclinical models | |
| Keywords | dc.subject | Rotenon | |
| Keywords | dc.subject | Translational medicine | |
| Título | dc.title | Neurotoxins as Preclinical Models for Parkinson’s Disease | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile