Extranodal lymphomas in the public health system in Chile: Analysis of 1251 patients from the National Adult Cancer Program
Author
dc.contributor.author
Peña, Camila
Author
dc.contributor.author
Russo, Moises
Author
dc.contributor.author
Martinez, Virginia
Author
dc.contributor.author
Cabrera, Maria Elena
Admission date
dc.date.accessioned
2019-03-18T12:03:41Z
Available date
dc.date.available
2019-03-18T12:03:41Z
Publication date
dc.date.issued
2019
Cita de ítem
dc.identifier.citation
Hematol Oncol
. 2019 Feb;37(1):47-53
Identifier
dc.identifier.issn
10991069
Identifier
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02780232
Identifier
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10.1002/hon.2547
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/167639
Abstract
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The aim of the study was to describe the clinical and epidemiological characteristics,
anatomic and histologic distribution, and treatment results of extranodal lymphomas
(ENLs), diagnosed and treated in the public health system in Chile. We included
patients with ENL diagnosed from 1998 to 2014, in 17 cancer centers, registered
prospectively in the database of the National Adult Cancer Program (PANDA) of
the Ministry of Health. Treatment was based on the local protocols for each lym phoma subtype. Extranodal lymphoma was documented in 1215 of 4907 non‐
Hodgkin lymphomas diagnosed in that period (25%). Median age was 59 years
(range, 16‐95), and 55% were female. The gastrointestinal (GI) tract was the most
common location (38%), followed by the head and neck (24%) and the skin (15%).
B‐cell lymphomas accounted for 78% of cases, diffuse large B‐cell lymphoma being
the most common histologic subtype (68%). Mycosis fungoides/Sezary syndrome
was the most frequent T‐cell subtype (36%), followed by NK/T‐cell lymphomanasal
type (24%). In comparison with western countries, Chile showed a significantly high
prevalence of NK/T‐cell lymphoma nasal type, while the frequency of B‐cell ENL
and the anatomic distribution appeared similar, being GI the most commonly
involved site.