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Authordc.contributor.authorDossi, Camila G. 
Authordc.contributor.authorGonzález Mañán, Daniel Alonso 
Authordc.contributor.authorRomero, Nalda 
Authordc.contributor.authorSilva, David 
Authordc.contributor.authorVidela Cabrera, Luis 
Authordc.contributor.authorTapia Opazo, Gladys 
Cita de ítemdc.identifier.citationFood and Function, Volumen 9, Issue 9, 2018, Pages 4847-4857
Abstractdc.description.abstract© The Royal Society of Chemistry. Ischemia-reperfusion (IR) is a deleterious condition associated with liver transplantation or resection that involves pro-oxidant and pro-inflammatory mechanisms. Considering that Rosa Mosqueta (RM) oil composition is rich in protective components such as α-linolenic acid (ALA) and tocopherols, we studied the effects of RM oil supplementation given prior to an IR protocol. Male Sprague-Dawley rats receiving RM oil (0.4 mL d−1) for 21 days were subjected to 1 h of ischemia followed by 20 h reperfusion. Parameters of liver injury (serum transaminases, histology), oxidative stress [liver contents of protein carbonyls, thiobarbituric acid reactants, Nrf2 activity and its target mRNA expression of heme oxygenase-1 (HO-1) and NADPH-quinone oxidoreductase-1 (NQO-1)] and inflammation [nuclear factor-κB (NF-κB) and its target mRNA expression of tumor necrosis factor-α (TNF-α) and interleukine-1β (IL-1β)] were studied. RM oil increased liver ALA and its derived
Publisherdc.publisherRoyal Society of Chemistry
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceFood and Function
Keywordsdc.subjectFood Science
Títulodc.titleAnti-oxidative and anti-inflammatory effects of Rosa Mosqueta oil supplementation in rat liver ischemia-reperfusion
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile