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Authordc.contributor.authorRoco, Ángela 
Authordc.contributor.authorCerda, Berta 
Authordc.contributor.authorCayún, Juan Pablo 
Authordc.contributor.authorLavanderos, Alejandra 
Authordc.contributor.authorRubilar, Juan Carlos 
Authordc.contributor.authorCerro, Roberto 
Authordc.contributor.authorAcevedo, Christian 
Authordc.contributor.authorCáceres, Dante 
Authordc.contributor.authorVarela, Nelson 
Authordc.contributor.authorQuiñones, Luis A. 
Admission datedc.date.accessioned2019-03-18T12:03:51Z
Available datedc.date.available2019-03-18T12:03:51Z
Publication datedc.date.issued2018
Cita de ítemdc.identifier.citationRevista Chilena de Pediatria, Volumen 89, Issue 4, 2018, Pages 432-440
Identifierdc.identifier.issn07176228
Identifierdc.identifier.issn03704106
Identifierdc.identifier.other10.4067/S0370-41062018005000709
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/167689
Abstractdc.description.abstract© 2018, Sociedad Chilena de Pediatria. All rights reserved. Cancer is the second leading cause of death in the world, causing 8.8 million deaths in 2015 according to the World Health Organization (WHO). Risk factors for cancer include smoking and alcohol consumption. In Chile, 33.6% of the population and 21.2% of young people smokes. Alcohol consumption in the Chilean population is 74.5% and 12.2% in young people. Among the physiological factors that influence the development of cancer, the genetic factor plays a relevant role. It has been shown that the presence of genetic polymorphisms that alter the ability of the body to eliminate contaminants increase the risk of developing cancer. The same applies to polymorphisms that prevent DNA repair due to damage caused by environmental pollutants such as cigarette smoke. The objective of this review is to analyze the state of the art of the relationship between pharmacogenetics, smoking, and alcohol consumption as risk factors for the devel
Lenguagedc.language.isoen
Publisherdc.publisherSociedad Chilena de Pediatria
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceRevista Chilena de Pediatria
Keywordsdc.subjectAlcohol
Keywordsdc.subjectCancer
Keywordsdc.subjectPharmacogenetics
Keywordsdc.subjectTobacco
Títulodc.titlePharmacogenetics, tobacco, alcohol and its effect on the risk development cancer Farmacogenética, tabaco, alcohol y su efecto sobre el riesgo de desarrollar cáncer
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile