Study on the relationship between wall shear stress and aspect ratio of cerebral aneurysms with different pressure differences using cfd simulations
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Aranda, Alfredo
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Study on the relationship between wall shear stress and aspect ratio of cerebral aneurysms with different pressure differences using cfd simulations
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Abstract
CFD simulations were performed for 60 human cerebral aneurysms (30 previously ruptured
and 30 previously unruptured) to study the behavior of the time-averaged wall shear stress
(TAWSS) with respect to the aspect ratio (AR), implementing a set of low, normal, and highpressure differences between the inlet and the outlets of each artery. It is well known that there
exists a direct relationship between TAWSS and the rupture. In this investigation, we presented an important result because the condition of the pressure among the branches and the
AR may be measured in any patient, then a slope may be associated, and finally a TAWSS may
be estimated. We found that when the pressure difference increased, the absolute slopes between TAWSS and AR increased as well. Also, the magnitude of the slope in the previously
unruptured aneurysms was 4.7 times the slope in the previously ruptured aneurysms. On the
other hand, TAWSS was higher in the previously unruptured aneurysm than previously
ruptured aneurysms due to the unruptured aneurysms that have a smaller surface area. Furthermore, we analyzed the relationship between TAWSS and other geometric parameters of
the aneurysm, such as bottleneck and non-sphericity index; however, no correlation was found
for either cases.
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Artículo de publicación SCOPUS
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URI: https://repositorio.uchile.cl/handle/2250/169431
DOI: 10.1142/S0219519418500550
ISSN: 02195194
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Journal of Mechanics in Medicine and Biology, Volumen 18, Issue 5, 2018, Pages 1850055-1 - 1850055-16
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