Chromosome progression and mitotic times behavior are mimicked by an stochastic unstable dynamics
Artículo

Open/ Download
Publication date
2018Metadata
Show full item record
Cómo citar
Cabrera Fernández, Juan
Cómo citar
Chromosome progression and mitotic times behavior are mimicked by an stochastic unstable dynamics
Abstract
Mitosis is one of the most important processes of living matter. In this paper we analyze the consequences of assuming mitosis as being dictated by an unstable dynamics grounded in an antagonist genetic circuit. Based on this approach main characteristics of chromosome movement behavior in different mitotic stages can be mimicked. We describe the statistical variability of mitotic progression times – an aspect unvisited in previous studies – and find a remarkable relationship between mitosis times, both in healthy and malignant eukaryotic cells. We propose a tentative methodological approach to reconstruct the mitotic dynamical attractor.
Indexation
Artículo de publicación SCOPUS
Identifier
URI: https://repositorio.uchile.cl/handle/2250/169548
DOI: 10.1016/j.physa.2018.08.139
ISSN: 03784371
Quote Item
Physica A: Statistical Mechanics and its Applications, Volumen 512, 2018, Pages 1121-1127
Collections