Health-promoting activities of edible seaweed extracts from Chilean coasts: assessment of antioxidant, anti-diabetic, anti-inflammatory and antimicrobial potential
Author
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García, Vivian
Author
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Uribe, Elsa
Author
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Vega Gálvez, Antonio
Author
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Delporte Vergara, Carla
Author
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Valenzuela Barra, Gabriela
Author
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López, Jéssica
Author
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Pasten, Alexis
Admission date
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2021-03-31T20:55:26Z
Available date
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2021-03-31T20:55:26Z
Publication date
dc.date.issued
2020
Cita de ítem
dc.identifier.citation
Rev Chil Nutr 2020; 47(5 ): 792-800
es_ES
Identifier
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10.4067/S0717-75182020000500792
Identifier
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https://repositorio.uchile.cl/handle/2250/178899
Abstract
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The aim of this study was to evaluate the antioxidant, antidiabetic, anti-inflammatory and antimicrobial activities of three edible seaweed extracts from Chilean coasts: Pyropia orbicularis, Ulva spp, and Durvillaea antarctica. Seaweed extracts in methanol and 70% acetone were performed to evaluate antioxidant and antidiabetic activities, whereas 60% methanol was used to measure anti-inflammatory and antimicrobial activities. Acetone extracts from D. antarctica had the highest total phenolic content and consequently exhibited the strongest antioxidant activity, while methanol extract of this seaweed presented the highest a-glucosidase inhibition (IC50= 0.004 mg mL(-1)). In the tests against E. coli and Penicillium sp., the extracts obtained from Ulva spp. were the most effective and exhibited the maximum anti-inflammatory effect against phorbol 12-myristate 13-acetate irritant agent (61.8% inhibition) in mice. Results indicated that all evaluated Chilean seaweed extracts are promising candidates for application in functional foods and in the pharmaceutical industry.
es_ES
Patrocinador
dc.description.sponsorship
Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT)
CONICYT FONDECYT
1160597
DIDULS (Direccion de Investigacion y Desarrollo de la Universidad de La Serena)
PT18331
Health-promoting activities of edible seaweed extracts from Chilean coasts: assessment of antioxidant, anti-diabetic, anti-inflammatory and antimicrobial potential
es_ES
Title in another language
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Actividades promotoras de la salud de extractos de algas comestibles de las costas chilenas: evaluación del potencial antioxidante, antidiabético, antiinflamatorio y antimicrobiano