Show simple item record

Authordc.contributor.authorSlachevsky Chonchol, Andrea 
Authordc.contributor.authorZitko, Pedro 
Authordc.contributor.authorMartínez Pernía, David 
Authordc.contributor.authorForno, Gonzalo 
Authordc.contributor.authorCourt, Felipe A. 
Authordc.contributor.authorLillo, Patricia 
Authordc.contributor.authorVillagra Castro, Roque 
Authordc.contributor.authorDurán Aniotz, Claudia Andrea 
Authordc.contributor.authorParrao, Teresa 
Authordc.contributor.authorAssar, Rodrigo 
Authordc.contributor.authorOrellana, Paulina 
Authordc.contributor.authorToledo, Carolina 
Authordc.contributor.authorRivera, Rodrigo 
Authordc.contributor.authorIbáñez, Agustín 
Authordc.contributor.authorParra, Mario A. 
Authordc.contributor.authorGonzález Billault, Christian 
Authordc.contributor.authorAmieva, Helena 
Authordc.contributor.authorThumala, Daniela 
Cita de ítemdc.identifier.citationBMC Geriatrics (2020) 20:505es_ES
Abstractdc.description.abstractBackground: With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system. In Chile, dementia is one of the most important causes of disability in the elderly and the most rapidly growing cause of death in the last 20 years. Cognitive complaint is considered a predictor for cognitive and functional decline, incident mild cognitive impairment, and incident dementia. The GERO cohort is the Chilean core clinical project of the Geroscience Center for Brain Health and Metabolism (GERO). The objective of the GERO cohort is to analyze the rate of functional decline and progression to clinical dementia and their associated risk factors in a community-dwelling elderly with subjective cognitive complaint, through a populationbased study. We also aim to undertake clinical research on brain ageing and dementia disorders, to create data and biobanks with the appropriate infrastructure to conduct other studies and facilitate to the national and international scientific community access to the data and samples for research. Methods: The GERO cohort aims the recruitment of 300 elderly subjects (> 70 years) from Santiago (Chile), following them up for at least 3 years. Eligible people are adults not diagnosed with dementia with subjective cognitive complaint, which are reported either by the participant, a proxy or both. Participants are identified through a household census. The protocol for evaluation is based on a multidimensional approach including socio-demographic, biomedical, psychosocial, neuropsychological, neuropsychiatric and motor assessments. Neuroimaging, blood and stool samples are also obtained. This multidimensional evaluation is carried out in a baseline and 2 follow-ups assessments, at 18 and 36months. In addition, in months 6, 12, 24, and 30, a telephone interview is performed in order to keep contact with the participants and to assess general well-being. Discussion: Our work will allow us to determine multidimensional risks factors associated with functional decline and conversion to dementia in elderly with subjective cognitive complain. The aim of our GERO group is to establish the capacity to foster cutting edge and multidisciplinary research on aging in Chile including basic and clinical research.es_ES
Patrocinadordc.description.sponsorshipInteramerican Development Bank (IDB) Multi-partner consortium to expand dementia research in Latin America (ReDLat) United States Department of Health & Human Services National Institutes of Health (NIH) - USA R01AG057234 Alzheimer's Association SG-20-725707 Rainwater Charitable Foundation Global Brain Health Institute Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) ANID/FONDECYT Regular 602/1171200 ANPCyT FONCyT 2017-1818 2017-1820 ANID/FONDAP 15150012 Alzheimer's Association UK-20-639295 United States Department of Health & Human Services National Institutes of Health (NIH) - USA NIH National Institute on Aging (NIA) R01 AG057234 ANID/FONDAP/15150012es_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.uri*
Sourcedc.sourceBMC Geriatricses_ES
Keywordsdc.subjectCognitive aginges_ES
Keywordsdc.subjectSubjective cognitive complaintes_ES
Keywordsdc.subjectFunctional declinees_ES
Títulodc.titleGERO cohort protocol, Chile, 2017–2022: community-based cohort of functional decline in subjective cognitive complaint elderlyes_ES
Document typedc.typeArtículo de revistaes_ES
dcterms.accessRightsdcterms.accessRightsAcceso Abierto
Indexationuchile.indexArtículo de publicación ISI
Indexationuchile.indexArtículo de publicación SCOPUS

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile