Getting intimate: lysosomes and ER rendezvous to control autophagy
Author
dc.contributor.author
Pihán, Philippe
Author
dc.contributor.author
Hetz Flores, Claudio
Admission date
dc.date.accessioned
2021-09-09T13:44:05Z
Available date
dc.date.available
2021-09-09T13:44:05Z
Publication date
dc.date.issued
2020
Cita de ítem
dc.identifier.citation
Cell Calcium 91 (2020) 102249
es_ES
Identifier
dc.identifier.other
10.1016/j.ceca.2020.102249
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/181900
Abstract
dc.description.abstract
The endoplasmic reticulum (ER) is the source of lysosomal calcium. The finding that the protein TMBIM6 -a putative ER calcium channel and cell death regulator-promotes calcium transfer from the ER to lysosomes to induce autophagy uncovers a missing piece in the puzzle of inter-organelle communication.
es_ES
Patrocinador
dc.description.sponsorship
Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT)
CONICYT FONDECYT 3200716
1180186
ANID/FONDAP program 15150012
Takeda Pharmaceutical Company Ltd P09-015-F
Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT) C17S02