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Authordc.contributor.authorDovale Rosabal, Gretel
Authordc.contributor.authorRodríguez Melis, Alicia
Authordc.contributor.authorEspinosa Escalona, Berta Alejandra
Authordc.contributor.authorBarriga Pinto, Gonzalo Andrés
Authordc.contributor.authorAubourg Martín, Santiago Pedro
Cita de ítemdc.identifier.citationMolecules 2021, 26, 3094es_ES
Abstractdc.description.abstractThere is consistent evidence that long-chain polyunsaturated fatty acids (LCPUFA) belonging to the n-3 series, i.e., eicosapentaenoic (20:5n-3, EPA) and docosahexaenoic (22:6n-3, DHA) acids, decrease the risk of heart, circulatory and inflammatory diseases. Furthermore, the bioavailability of such fatty acids has been shown to depend on their location in triacylglycerol (TG) molecules at the sn-2 position. Consequently, great attention has been accorded to the synthesis of structured acylglycerols (sAG), which include EPA or DHA at the sn-2 position. The aim of this work was to synthesize sAG starting from deodorized refined commercial salmon oil. For this, immobilized lipase B from Candida antarctica (nonspecific) was used as a catalyst for the intra-interesterification process under CO2 supercritical conditions (CO2SC). According to the CO2SC reaction time, three different fractions including sAG compounds were obtained. The location of EPA and DHA at the sn-2 position in the resulting glycerol backbone was identified by mass spectrometry (MALDI-TOF) analysis. In all fractions obtained, a marked decrease in the starting TG content was observed, while an increase in the DHA content at the sn-2 position was detected. The fraction obtained after the longest reaction time period (2 h) led to the highest yield of sn-2 position DHA in the resulting sAG molecule.es_ES
Patrocinadordc.description.sponsorshipComision Nacional de Investigacion Cientifica y Tecnologica (CONICYT) CONICYT FONDECYT 1181774es_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
Link to Licensedc.rights.uri*
Keywordsdc.subjectn-3 LCPUFAes_ES
Keywordsdc.subjectEPA/DHA sn-2 positiones_ES
Keywordsdc.subjectSalmon oiles_ES
Keywordsdc.subjectImmobilized lipase Bes_ES
Keywordsdc.subjectCandida antarctica (nonspecific)es_ES
Keywordsdc.subjectCO2 supercritical extractiones_ES
Keywordsdc.subjectStructured acylglycerolses_ES
Títulodc.titleSynthesis of EPA- and DHA-enriched structured acylglycerols at the sn-2 position starting from commercial salmon oil by enzymatic lipase catalysis under supercritical conditionses_ES
Document typedc.typeArtículo de revistaes_ES
dc.description.versiondc.description.versionVersión publicada - versión final del editores_ES
dcterms.accessRightsdcterms.accessRightsAcceso abiertoes_ES
Indexationuchile.indexArtículo de publícación WoSes_ES

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Attribution-NonCommercial-NoDerivs 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States