Performance of SARS-CoV-2 rapid antigen test compared with real-time RT-PCR in asymptomatic individuals
Author
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Peña, Mónica
Author
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Ampuero Martínez, Manuel Andrés
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Garcés, Carlos
Author
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Gaggero Brillouet, Aldo Andres
Author
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García, Patricia
Author
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Velásquez, María Soledad
Author
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Luza, Ricardo
Author
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Álvarez, Pía
Author
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Paredes, Fabio
Author
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Acevedo, Johanna
Author
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Farfán Urzúa, Mauricio Javier
Author
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Solari, Sandra
Author
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Soto Rifo, Ricardo Andrés
Author
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Valiente Echeverría, Fernando Andrés
Admission date
dc.date.accessioned
2021-11-05T12:22:13Z
Available date
dc.date.available
2021-11-05T12:22:13Z
Publication date
dc.date.issued
2021
Cita de ítem
dc.identifier.citation
International Journal of Infectious Diseases 107 (2021) 201–204
es_ES
Identifier
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10.1016/j.ijid.2021.04.087
Identifier
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https://repositorio.uchile.cl/handle/2250/182597
Abstract
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Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) and RT-PCR in 842 asymptomatic individuals from Tarapaca, Chile. A sensitivity of 69.86%, specificity of 99.61%, PPV of 94.44% and NPP of 97.22% with Ct values (Ct > 27) that were significantly higher among individuals with false-negative RAT were reported. These results support the fact that RAT might have a significant impact on the identification of asymptomatic carriers in areas that lack suitable laboratories to perform SARS-CoV-2 real-time RT-PCR diagnostics, or the results take more than 24-48 h, as well as zones with high traffic of individuals such as border/customs, airports, interregional bus, train stations or in any mass testing campaign requiring rapid results.
es_ES
Patrocinador
dc.description.sponsorship
Ministerio de Salud de Chile
ANID Chile through Fondecyt 1181656
1190156
1180798/1211547
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Lenguage
dc.language.iso
en
es_ES
Publisher
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Elsevier
es_ES
Type of license
dc.rights
Attribution-NonCommercial-NoDerivs 3.0 United States