Aspectos estructurales de la interrelación entre lípidos y proteínas en membranas.
Professor Advisor
dc.contributor.advisor
Doggenweiler Figueroa, Carlos
Author
dc.contributor.author
Elías Muñoz, Ramon J.F.
Admission date
dc.date.accessioned
2021-12-20T18:29:16Z
Available date
dc.date.available
2021-12-20T18:29:16Z
Publication date
dc.date.issued
1978
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/183298
Abstract
dc.description.abstract
The interpretation of the processes that occur in relation with biological membranes or membrane-bound organeles, is intimately related with the organization of these membranes, thus, advances in the knowledge of the structure and molecular relationships are of foremost importance to the understanding of their biological properties.
We have applied the freeze-etching to a model membrane (a complex lipid bilayer), a novel method that produces no chemical alteration to the bilayers.
Observations of Platinum - or Chromium -n- shadowed replicas under the Electron Microscope show that hemocyanin and/or their subunits penetrate in the depth of the bilayer and appear themselves covered on both sides by the lipids. The application of freeze-etching to photoreceptors demonstrates that the disc membrane have an asymmetrical protein distribution.
In conclusion: the current concept of biological membrane structure cannot be applied fully to our membrane model and probably neither to any type of membrane; in fact, each active membrane has an peculiar organization to be understood in terms of its biological function.
es_ES
Lenguage
dc.language.iso
es
es_ES
Publisher
dc.publisher
Universidad de Chile
es_ES
Type of license
dc.rights
Attribution-NonCommercial-NoDerivs 3.0 United States