The multi-partner consortium to expand dementia research in Latin America (ReDLat): Driving multicentric research and implementation science
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Ibáñez, Agustín
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The multi-partner consortium to expand dementia research in Latin America (ReDLat): Driving multicentric research and implementation science
Author
- Ibáñez, Agustín;
- Yokoyama, Jennifer S.;
- Possin, Katherine L.;
- Matallana, Diana;
- Lopera, Francisco;
- Nitrini, Ricardo;
- Takada, Leonel T.;
- Custodio, Nilton;
- Sosa Ortiz, Ana Luisa;
- Ávila Funes, José Alberto;
- Behrens Pellegrino, María Isabel;
- Slachevsky Chonchol, Andrea María;
- Myers, Richard M.;
- Cochran, J. Nicholas;
- Brusco, Luis Ignacio;
- Bruno, Martín A.;
- Brucki, Sonia M. D.;
- Piña Escudero, Stefanie Danielle;
- Oliveira, Maira Okada de;
- Kehoe, Patricio Donnelly;
- García, Adolfo M.;
- Cardona, Juan Felipe;
- Santamaría García, Hernando;
- Moguilner, Sebastián;
- Durán Aniotz, Claudia;
- Tagliazucchi, Enzo;
- Maito, Marcelo;
- Longoria Ibarrola, Erika Mariana;
- Pintado Caipa, Maritza;
- Godoy, María Eugenia;
- Bakman, Vera;
- Javandel, Shireen;
- Kosik, Kenneth S.;
- Valcour, Víctor;
- Miller, Bruce L.;
Abstract
Dementia is becoming increasingly prevalent in Latin America, contrasting with stable
or declining rates in North America and Europe. This scenario places unprecedented
clinical, social, and economic burden upon patients, families, and health systems. The
challenges prove particularly pressing for conditions with highly specific diagnostic
and management demands, such as frontotemporal dementia. Here we introduce
a research and networking initiative designed to tackle these ensuing hurdles, the
Multi-partner consortium to expand dementia research in Latin America (ReDLat). First,
we present ReDLat’s regional research framework, aimed at identifying the unique
genetic, social, and economic factors driving the presentation of frontotemporal dementia
and Alzheimer’s disease in Latin America relative to the US. We describe ongoing
ReDLat studies in various fields and ongoing research extensions. Then, we introduce
actions coordinated by ReDLat and the Latin America and Caribbean Consortium
on Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regional
visibility and capacity building, diplomatic coordination in local priority areas, and a
knowledge-to-action framework toward a regional action plan. Together, these research
and networking initiatives will help to establish strong cross-national bonds, support the
implementation of regional dementia plans, enhance health systems’ infrastructure, and
increase translational research collaborations across the continent.
Patrocinador
Multi-partner Consortium to Expand Dementia Research in Latin America [ReDLat, by National Institutes of Health, National Institutes of Aging] R01 AG057234
Multi-partner Consortium to Expand Dementia Research in Latin America [Alzheimer's Association] SG-20-725707
Multi-partner Consortium to Expand Dementia Research in Latin America [Rainwater Charitable Fundation-Tau]
Multi-partner Consortium to Expand Dementia Research in Latin America [Global Brain Health Institute]
Takeda Pharmaceutical Company Ltd CW2680521
Alzheimer's Association GBHI ALZ UK-20-639295
Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) ANID/FONDAP/15150012
Sistema General de Regalias BPIN2018000100059
Universidad del valle CI 5316
Inter-American Development Bank (IDB)
ANID/FONDEF ID20I10152
2018-AARG-591107
Indexation
Artículo de publícación WoS Artículo de publicación SCOPUS
Quote Item
Frontiers in Neurology March 2021 Volume 12 Article 631722
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