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Authordc.contributor.authorBustamante Loyola, Jorge
Authordc.contributor.authorPérez Retamal, Marcela
Authordc.contributor.authorMendiburo Seguel, Andrés
Authordc.contributor.authorGuedeney, Antoine Claude
Authordc.contributor.authorSalinas González, Ricardo
Authordc.contributor.authorMuñoz Jiménez, Lucia
Authordc.contributor.authorCox Melane, Horacio
Authordc.contributor.authorGonzález Mas, José Miguel
Authordc.contributor.authorSimó Teufel, Sandra
Authordc.contributor.authorMorgues Nudman, Mónica
Admission datedc.date.accessioned2022-07-05T15:21:30Z
Available datedc.date.available2022-07-05T15:21:30Z
Publication datedc.date.issued2022
Cita de ítemdc.identifier.citationFront. Pediatr. 10:803932.es_ES
Identifierdc.identifier.other10.3389/fped.2022.803932
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/186471
Abstractdc.description.abstractBackground: Sustained social withdrawal is a key indicator of child emotional distress and a risk factor for psychological development. Preterm infants have a higher probability of developing sustained social withdrawal than infants born full-term during their first year.& nbsp;Objective: To compare the effect of a behavioral guidance intervention to that of routine pediatric care on sustained social withdrawal behavior in preterm infants.& nbsp;Design: Multicenter randomized clinical trial.& nbsp;Participants: Ninety nine moderate and late preterm newborns and their parents were recruited and randomized into two groups, i.e., Intervention (n = 49) and Control (n = 50). Both groups attended medical check-ups at 2, 6 and 12 months and were assessed with the Alarm Distress Baby Scale. The intervention group received a standardized behavioral intervention if the neonatologist detected sustained social withdrawal. Also, parents filled out the Edinburgh Postnatal Depression Scale, the modified-Perinatal Posttraumatic Stress Disorder Questionnaire, and the Impact of Event Scale-revised.& nbsp;Results: At baseline, the prevalence of withdrawal was 4.0% (95% CI: 0.03-14.2) for the control group and 22.4% (95% CI: 13.0-35.9) for the intervention group [OR = 0.22, p = 0.028 (95% CI =0.06-0.84)]. At 6 months, the prevalence was 10.0% (95% CI: 3.9-21.8) for the control group and 6.1% (95% CI: 2.1-16.5) for the intervention group [OR = 2.09, p = 0.318 (95% CI = 0.49-8.88)]. At 12 months, the prevalence was 22.0% (95% CI: 12.8-35.2) for the control group and 4.1% (95% CI: 1.1-13.7) for the intervention group [OR = 6.63, p = 0.018 (95% CI = 1.39-31.71)]. Logistic generalized estimating equation models were performed. The pooled crude OR (considering diagnosis at 6 and 12 months) was 3.54 [p = 0.022 (95% CI = 1.20-10.44); Cohen's d= 0.70]. In the case of pooled adjusted OR, the model considered diagnosis (0 = Withdrawal, 1 = Normal) as the dependent variable, time of evaluation (1= 6 months, 2 = 12 months) and group (0 = Control, 1 = Experimental) as factors. In this case, the pooled adjusted OR was 3.57 [p = 0.022 (95% CI = 1.20-10.65); Cohen's d = 0.70].& nbsp;Conclusion: Assessment and intervention of sustained social withdrawal in preterm infants via standardized instruments benefits families by reducing its prevalence, and possible associated negative outcomes.es_ES
Patrocinadordc.description.sponsorshipAcademic and Scientific Department of Clinica Alemana de Santiagoes_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherMDPIes_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
Sourcedc.sourceFrontiers in Pediatricses_ES
Keywordsdc.subjectSocial withdrawales_ES
Keywordsdc.subjectPreterm (birth)es_ES
Keywordsdc.subjectEarly detectiones_ES
Keywordsdc.subjectEmotional distresses_ES
Keywordsdc.subjectInteractive guidancees_ES
Keywordsdc.subjectPostnatal depressiones_ES
Keywordsdc.subjectPosttraumatic stress (PTS)es_ES
Keywordsdc.subjectSocial developmentes_ES
Títulodc.titleThe impact of an interactive guidance intervention on sustained social withdrawal in preterm infants in Chile: randomized controlled triales_ES
Document typedc.typeArtículo de revistaes_ES
dc.description.versiondc.description.versionVersión publicada - versión final del editores_ES
dcterms.accessRightsdcterms.accessRightsAcceso abiertoes_ES
Catalogueruchile.catalogadorapces_ES
Indexationuchile.indexArtículo de publícación WoSes_ES


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