Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 37901-37920 of 98742

    • A worldwide perspective of nursing home-acquired pneumonia compared with community-acquired pneumonia 
      Liapikou, Adamantia; Polverino, Eva; Cilloniz, Catia; Peyrani, Paulo; Ramírez, Julio; Menéndez, Rosario; Torres, Antoni (American Association for Respiratory Care, 2014)
      Nursing home-acquired pneumonia (NHAP) is the leading cause of death among long-term care patients and the second most common cause of transfers to acute care facilities. The aim of this study was to characterize the ...
    • Descripción de los cambios en la velocidad media de flujo sanguíneo cerebral en posición supino y sedente, ... 
      Merino Osorio, Catalina; Heap, Pía; Vergara, Valentina; Yáñez, Alonso; Rivera, Rodrigo (Sociedad Médica de Santiago, 2014)
      Background: Early mobilization in intensive care units (ICU) provides respiratory, neurological and cardiovascular benefits in hospitalized patients. However, the orthostatic effects of changing from a supine to a sitting ...
    • GFP labelling and epigenetic enzyme expression of bone marrow-derived mesenchymal stem cells from bovine foetuses 
      Díaz, P.; Cuevas, F.; Peralta, O. A. (Elsevier, 2015)
      Mesenchymal stem cells (MSC) are multipotent progenitor cells defined by their ability to self-renew and give rise to differentiated progeny. Since MSC from adult tissues represent a promising source of cells for a wide ...
    • The phenotypic spectrum of SCN8A encephalopathy 
      Larsen, Jan; Carvill, Gemma L.; Gardella, Elena; Kluger, Gerhard; Schmiedel, Gudrun; Barisic, Nina; Depienne, Christel; Brilstra, Eva; Mang, Yuan; Nielsen, Jens Erik Klint; Kirkpatrick, Martin; Goudie, David; Goldman, Rebecca; Jähn, Johanna A.; Jepsen, Birgit; Gill, Deepak; Döcker, Miriam; Biskup, Saskia; McMahon, Jacinta M.; Koeleman, Bobby; Harris, Mandy; Braun, Kees; De Kovel, Carolien G.F.; Marini, Carla; Specchio, Nicola; Djémié, Tania; Weckhuysen, Sarah; Tommerup, Niels; Troncoso, Mónica; Troncoso, Ledia; Bevot, Andrea; Wolff, Markus; Hjalgrim, Helle; Guerrini, Renzo; Scheffer, Ingrid E.; Mefford, Heather C.; Møller, Rikke S. (Lippincott Williams and Wilkins, 2015)
      Objective:SCN8A encodes the sodium channel voltage-gated 8-subunit (Na(v)1.6). SCN8A mutations have recently been associated with epilepsy and neurodevelopmental disorders. We aimed to delineate the phenotype associated ...
    • Comparación del consumo de vitaminas y minerales en adultos mayores chilenos según estado nutricional 
      Durán A., Samuel; Ulloa A., Alejandra; Reyes G., Sussanne (Sociedad Médica de Santiago, 2014)
      Background: An adequate consumption of micro and macro nutrients is essential to maintain an adequate health among older people. Aim: To compare the consumption of micro- and macronutrients in older people from three ...
    • Trypanosoma cruzi induces trophoblast differentiation: A potential local antiparasitic mechanism of the ... 
      Liempi, A.; Castillo, C.; Duaso, J.; Droguett, D.; Sandoval, A.; Barahona, K.; Hernández, A.; Galanti Garrone, Norbel; Maya Arango, Juan; Kemmerling Weis, Ulrike (W.B. Saunders, 2014)
      Introduction: The congenital transmission of Trypanosoma cruzi (T. cruzi) is responsible for one-third of new Chagas disease cases each year. During congenital transmission, the parasite breaks down the placental barrier ...
    • Microarray analysis of the Escherichia coli response to CdTe-GSH Quantum Dots: Understanding the bacterial ... 
      Monrás, Juan P.; Collao, Bernardo; Molina Quiroz, Roberto C.; Pradenas, Gonzalo A.; Saona, Luis A.; Durán Toro, Vicente; Órdenes Aenishanslins, Nicolás; Venegas, Felipe A.; Loyola, David E.; Bravo, Denisse; Calderón, Paulina F.; Calderón, Iván L.; Vásquez, Claudio C.; Chasteen, Thomas G.; López, Desiré A.; Pérez Donoso, José M. (BioMed Central, 2014)
      Background: Most semiconductor nanoparticles used in biomedical applications are made of heavy metals and involve synthetic methods that require organic solvents and high temperatures. This issue makes the development of ...
    • Intasome architecture and chromatin density modulate retroviral integration into nucleosome 
      Benleulmi, Salah S.; Matysiak, Julien; Henríquez, Rodrigo R.; Vaillant, Cédric; Lesbats, Paul; Calmels, Christina; Naughtin, Monica; León, Oscar; Skalka, Anna Marie; Ruff, Marc; Lavigne, Marc; Andreola, Marie Line; Parissi, Vincent (BioMed Central, 2015)
      Background: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by ...
    • Propiedades psicométricas del cuestionario de calidad de vida relacionada con la salud KIDSCREEN-27 en ... 
      Molina González, Temístocles; Montaño Espinoza, Rosa; González Araya, Electra; Sepúlveda P., Rodrigo; Hidalgo-Rasmussen, Carlos; Martínez N., Vania; Molina Cartes, Ramiro; George L., Myriam (Sociedad Médica de Santiago, 2014)
      Background: KIDSCREEN-52, which assesses health related quality of life in adolescents, has been adapted and validated in Chile showing excellent psychometric properties. There is a shorter version of the instrument, ...
    • Obesidad en mujeres chilenas en edad fértil 
      Araya Bannout, Marcela; Padilla, Oslando; Garmendia Miguel, María Luisa; Atalah, Eduardo; Uauy Dagach-Imbarack, Ricardo (Sociedad Médica de Santiago, 2014)
      Background: Women in childbearing ages (WCBA) represent a strategic intervention group to reverse the global trend of increasing obesity. Aim: To conduct a review of studies reporting obesity prevalence in WCBA in Chile ...
    • Glycemic control and oxidative stress markers and their relationship with the thioredoxin interacting protein ... 
      Andrews Guzmán, Mónica; Arredondo Olguín, Miguel; Olivares Gronhert, Manuel (Grupo Aula Médica, 2015)
      Objective: To investigate the relationship between oxidative stress and biochemical parameters and the expression of TXNIP, IL-6, IL-1β and TNF-α in peripheral mononuclear cells (PMCs) from type-2 diabetic patients. Methods: ...
    • Ventilatory function and cardiovascular disease risk factors: A cross-sectional study in young adults 
      García Larsen, Vanessa; Bustos, Patricia; Amigo, Hugo; Potts, James; Rona, Roberto J. (BioMed Central, 2014)
      Background: The association between impaired lung function and cardiovascular disease (CVD) risk factors has been shown in adults. However, there is little evidence of such an association in young adults, particularly ...
    • Central obesity and not age increases skeletal muscle lipids, without influencing lean body mass and strength 
      Maza Cave, María Pía de la; Hirsch Birn, Sandra; Jara, Natalia; Leiva, Laura; Barrera, Gladys; Silva, Claudio; Pañella, Loreto; Henríquez, Sandra; Bunout Barnett, Daniel (Grupo Aula Médica, 2015)
      Background/Aims: To measure skeletal muscle lipid infiltration, its association with insulin resistance (IR) lean mass and function, in Chilean men differing in age and body composition. Our hypothesis was that muscle ...
    • Impact of living and socioeconomic characteristics on cardiovascular risk in ischemic stroke patients 
      Amarenco, Pierre; Abboud, Halim; Labreuche, Julien; Arauz, Antonio; Bryer, Alan; Lavados Germain, Pablo Manuel; Massaro, Ayrton; Muñoz Collazos, Mario; Steg, Philippe Gabriel; Yamout, Bassem I.; Vicaut, Eric (Blackwell, 2014)
      Objective We aimed to stratify the risk of vascular event recurrence in patients with cerebral infarction according to living and socioeconomic characteristics and geographic region. Method The Outcomes in Patients with ...
    • Hydration status after exercise affect resting metabolic rate and heart rate variability 
      Castro Sepúlveda, Mauricio; Cerda Kohler, Hugo; Pérez Luco, Cristian; Monsalves, Matías; Andrade, David Cristóbal; Zbinden Foncea, Hermann; Báez San Martín, Eduardo; Ramírez Campillo, Rodrigo (Grupo Aula Médica, 2015)
      Introduction: Heart rate variability and resting metabolic rate are commonly to assess athlete´s physiological status and energy requirements. Exercise-induced dehydration can reach up to 5% of body mass per hour. ...
    • Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas 
      Canals Cifuentes, Andrea; Cavada Chacón, Gabriel; Nazer Herrera, Julio (Sociedad Médica de Santiago, 2014)
      Background: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors ...
    • The effects of hormonal contraceptives on glycemic regulation 
      Cortés, Manuel E.; Alfaro, Andrea A. (Maney Publishing, 2014)
      A number of side effects have been linked to the use of hormonal contraceptives, among others, alterations in glucose levels. Hence, the objective of this mini-review is to show the main effects of hormonal contraceptive ...
    • Consumption of orange fermented beverage reduces cardiovascular risk factors in healthy mice 
      Escudero López, Blanca; Berná, Genoveva; Ortega, Ángeles; Herrero Martín, Griselda; Cerrillo, Isabel; Martín, Franz; Fernández Pachón, María Soledad (Elsevier, 2015)
      The consumption of fruits prevents the risk of cardiovascular diseases. Alcoholic fermentation has been carried out in fruits resulting in products which provide high concentration of bioactive compounds and variable alcohol ...
    • Iron overload-modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism ... 
      Alvarado Díaz, Carlos Patricio; Núñez González, Marco; Devoto, Luigi; González Ramos, Reinaldo (Elsevier, 2015)
      Objective: To evaluate the effect of iron overload on nuclear factor kappa-B (NF-kappa B) activation in human endometrial stromal cells (ESCs). Design: Experimental study. Setting: University hospital research ...
    • The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle ... 
      Llanos Vidal, Paola; Contreras Ferrat, Ariel; Georgiev, Tihomir; Osorio Fuentealba, César; Espinosa, Alejandra; Hidalgo, Jorge; Hidalgo Tapia, María Cecilia; Jaimovich Pérez, Enrique (American Physiological Society, 2015)
      Insulin stimulates glucose uptake in adult skeletal muscle by promoting the translocation of GLUT4 glucose transporters to the transverse tubule (T-tubule) membranes, which have particularly high cholesterol levels. We ...