Repositorio Académico de la Universidad de Chile: Recent submissions
Now showing items 40181-40200 of 98950
-
(Biophysical Society, 2007)We report a combined quantum mechanics/molecular mechanics (QM/MM) study to determine the protein-ligand interaction energy between CDK2 (cyclin-dependent kinase 2) and five inhibitors with the N2-substituted 6-cyclohexy ...
-
(2007)A great body of experimental evidence collected over many years indicates that calcium has a central role in a variety of neuronal functions. In particular, calcium participates in synaptic plasticity, a neuronal process ...
-
(2003)Viral infections, the main cause of encephalitis, invade CNS via bloodstream (e.: enterovirus), peripherical nerves (e.: rabies) and less frequently, via olfactory nerve (e.: free life amoebas). Focal neuron compromise ...
-
(Universidad de la Frontera, 2006)Reduction of O2 delivery to tissues damage them, including the seminiferous epithelium. Recently, population working in high altitude has increased, so that the study of hypobaric hypoxia on spermatogenesis becomes of ...
-
(2006)Background: Cardiovascular risk, growth failure and the new immunosuppressive drugs, have encouraged steroid withdrawal or total avoidance with promising results in renal transplant (Tx) immunosuppression. Aim: To evaluate ...
-
(2006)Backgrounds: There is a high prevalence of obesity and hyperinsulinism among Chilean prepuberal children. Aim: To evaluate insulin sensitivity (IS) using fasting insulin, the Homeostasis Model Assessment (HOMA) and ...
-
(2006)Increased expression of casein kinase 2 (CK2) is associated with hyperproliferation and suppression of apoptosis in cancer. Mutations in the tumor suppressor APC (adenomatous polyposis coli) are frequent in colon cancer ...
-
(2007)We compared the frequency of Pneumocystis in 126 sudden infant death syndrome (SIDS) cases with a control group of 24 infants from the San Diego SIDS/SUDC Research Project who died of accidental or inflicted injuries. Cysts ...
-
(Mary Ann Liebert Inc., 2006)Endometriosis is the proliferation of endometrial tissue outside the normal confines of the myometrium or uterine cavity. Endometriosis involving the urinary tract occurs in approximately 1% to 2% of cases. The bladder is ...
-
(2006)Multiple phosphorylation of β-catenin by glycogen synthase kinase 3 (GSK3) in the Wnt pathway is primed by CK1 through phosphorylation of Ser-45, which lacks a typical CK1 canonical sequence. Synthetic peptides encompassing ...
-
(2007)The endogenous cannabinoid receptor agonist anandamide (AEA) exerts vascular effects such as vasodilatation and hypotension. In this study, we determined the effect of AEA on endothelin-1 production by cultured human ...
-
(2006)Objective. To explore the Chilean health system financing based on the most recent available data. Material and Methods. Using the WHO World Health Report 2000 framework, this paper analyzes the Chilean health system ...
-
(2007)Chlorophenylmaleimide (CI-PhMI) and N-maleoylglycine (N-MG) with β-methylhydrogen itaconate (β-MHI) were copolymerized by radical polymerization, and their metal ion retention capacity (MRC) and thermal behavior were ...
-
(2006)Reactive astrocytes surround amyloid depositions and degenerating neurons in Alzheimer's disease (AD). It has been previously shown that β-amyloid peptide induces inflammatory-like responses in astrocytes, leading to ...
-
(2007)BACKGROUND: Incorporation of new rotavirus vaccines into national programs of developing countries will rely on well-designed cost-effective analysis based on accurate assessment of disease burden. For Chile, rotavirus ...
-
(2006)There is a relationship between child sexual abuse and adult psychopathology. We report a 35 year-old woman derived to the Psychiatric Service of the Curicó Hospital due to anxiety and depressive symptoms lasting eight ...
-
(2006)Background: Smoking is the main risk factor for Chronic Obstructive Pulmonary Disease (COPD), an important cause of morbidity and mortality. Aim: To estimate smoking attributable risk and population attributable risk in ...
-
(2006)Background: Microtia is a congenital defect characterized by disturbances in the size and form of the ear lobe. Anotia corresponds to the absence of the ear lobe. Aim: To study the prevalence of microtia and anotia at the ...
-
(2006)Background: Insects of the subfamily triatominae are the biological vectors of Trypanosoma cruzi, the causal agent of Chagas disease. Aim: To search for wild colonies of triatomines in the Metropolitan Region of Chile. ...
-
(2006)Background: There are great geographical differences in the incidence of type I diabetes mellitus. Aim: To determine the incidence rate of type 1 diabetes mellitus (DM1) in the Metropolitan Region of Santiago, Chile from ...
