Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 40621-40640 of 101786

    • Selective attention to visual stimuli using auditory distractors is altered in alpha-9 nicotinic receptor ... 
      Terreros, Gonzalo; Jorratt, Pascal; Aedo, Cristian; Elgoyhen, Ana Belén; Delano, Paul H. (Society for Neuroscience, 2016)
      © 2016 the authors. During selective attention, subjects voluntarily focus their cognitive resources on a specific stimulus while ignoring others. Top-down filtering of peripheral sensory responses by higher structures of ...
    • The ER proteostasis network in ALS: Determining the differential motoneuron vulnerability 
      Rozas, Pablo; Bargsted, Leslie; Martínez, Francisca; Hetz Flores, Claudio; Medinas Bilches, Danilo (Elsevier Ireland Ltd, 2017)
      © 2016 Elsevier Ireland Ltd Amyotrophic lateral sclerosis (ALS) is a fatal late-onset neurodegenerative disease characterized by the selective loss of motoneurons. The mechanisms underlying neuronal degeneration in ALS are ...
    • Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of ... 
      Briceño, Andrea; Muñoz, Patricia; Brito, Patricia; Huenchuguala, Sandro; Segura Aguilar, Juan; Paris Pizarro, Irmgard (Springer New York LLC, 2016)
      © 2015, Springer Science+Business Media New York.In this study, we investigated the role of adducts formation between aminochrome and tubulin and its interference in microtubules assembly and stability in aminochrome-induced ...
    • A four-year survey in the farming region of Chile, occurrence and human exposure to polychlorinated ... 
      San Martin, B. V.; Pizarro Aránguiz, Nicolás Javier; García Mendoza, Diego Tomás; Araya-Jordán, Carolina; Maddaleno Toledo, Aldo; Abad, E.; Galbán-Malagón, C. J. (Elsevier B.V., 2016)
      © 2016 Elsevier B.V.For the first time in South America, a four-year survey (2011–2014) was conducted to assess the occurrence of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) and dioxin-like polychlorinated ...
    • Chalcone-induced apoptosis through caspase-dependent intrinsic pathways in human hepatocellular carcinoma cells 
      Ramirez-Tagle, Rodrigo; Escobar, Carlos A.; Romero, Valentina; Montorfano, Ignacio; Armisén, Ricardo; Borgna, Vincenzo; Jeldes, Emanuel; Pizarro, Luis; Simon, Felipe; Echeverria, Cesar (MDPI AG, 2016)
      © 2016 by the authors; licensee MDPI, Basel, Switzerland. Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide. Chemoprevention of HCC can be achieved through the use of natural or synthetic ...
    • Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma 
      Riester, Scott M.; Torres-Mora, Jorge; Dudakovic, Amel; Camilleri, Emily T.; Wang, Wei; Xu, Fuhua; Thaler, Roman R.; Evans, Jared M.; Zwartbol, René; Briaire-de Bruijn, Inge H.; Maran, Avudaiappan; Folpe, Andrew L.; Inwards, Carrie Y.; Rose, Peter S.; Shives, Thomas C. (John Wiley and Sons Inc., 2017)
      © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. Osteoblastoma is a benign bone tumor that can often be difficult to distinguish from malignant osteosarcoma. Because misdiagnosis can result in ...
    • Detalles técnicos y morbimortalidad de la fundoplicatura de Nissen laparoscópica en 503 pacientes con reflujo ... 
      Csendes Juhasz, Attila; Díaz, Juan Carlos; Burdiles, Patricio; Maluenda, Fernando (Sociedad de Cirujanos de Chile, 2016)
      Background: Laparoscopic Nissen fundoplication is the surgical procedure of choice for patients with gastroesophageal reflux. Aim: To describe the most important surgical stages of the technique and report the rates of ...
    • Position paper from the department of ethics of the chilean college of physicians about conscientious ... 
      Salas, Sofía P.; Besio, Mauricio; Bórquez Estefó, Gladys; Salinas, Rodrigo A.; Valenzuela Yuraidini, Carlos; Micolich, Constanza; Novoa Sotta, Fernando; Bernier Villarroel, Lioniel; Montt M., Julio; Misseroni Raddatz, Adelio (Sociedad Medica de Santiago, 2016)
      © 2016, Sociedad Medica de Santiago. All Rights Reserved. The Chilean bill that regulates abortion for three cases (Bulletin N° 9895-11) includes the possibility that health professionals may manifest their conscientious ...
    • Fungal peritonitis due to Rhodotorula mucilaginosa in a patient with automated peritoneal dialysis. Literature ... 
      Verdugo, Fernando J.; Briones, Eduardo; Porte, Lorena; Amaro, José; Fica Cubillos, Alberto (Sociedad Chilena de Infectologia, 2016)
      © 2016, Sociedad Chilena de Infectologia. All rights reserved. Fungal peritonitis is a major complication of peritoneal dialysis associated with high mortality. Most survivors have a high rate of abandonment of peritoneal ...
    • A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes ... 
      Pouché, Lucie; Koitka, Matthias; Stojanova, Jana; Woillard, Jean Baptiste; Monchaud, Caroline; Villeneuve, Claire; Essig, Marie; Abraham, Julie; Le Meur, Yannick; Rerolle, Jean Phillippe; Kamar, Nassim; Rostaing, Lionel; Merville, Pierre; Gandia, Peggy; Bouchet, Stepha (Future Medicine Ltd., 2016)
      © 2016 Future Medicine Ltd.Aim: To investigate the potential influence of variants in genes involved in the calcineurin pathway on the efficacy and toxicity of calcineurin inhibitors in renal transplantation. Materials & ...
    • Adjusted Clinical Groups method (ACG) to allocate resources according to the disease burden of each health ... 
      Santelices Cuevas, Emilio; Muñoz P., Fernando; Muñiz, Patricio; Rojas, José (Sociedad Medica de Santiago, 2016)
      © 2016, Sociedad Medica de Santiago. All Rights Reserved. Background: Health care must be provided with strong primary health care models, emphasizing prevention and a continued, integrated and interdisciplinary care. Tools ...
    • Analysis of voriconazole serum concentrations and safety profile in pediatric oncology patients Análisis ... 
      Silva Marambio, Felipe; Navea, Daniel; Salas, Carolina; Torres, Juan P.; Catalán, Paula; Morales, Jorge (Sociedad Chilena de Infectologia, 2016)
      © 2016, Sociedad Chilena de Infectologia. All rights reserved.Background: Voriconazole (VCZ) serum drug levels (SDL) vary widely and are associated with increased mortality when they are below the therapeutic range for ...
    • Determinantes de la intención emprendedora: nueva evidencia 
      Soria Barreto, Karla; Zúñiga Jara, Sergio; Ruiz Campo, Sofía (Interciencia, 2016)
      En este estudio se analizan los determinantes de la intención emprendedora en estudiantes de una escuela de negocios universitaria chilena. En línea con los estudios clásicos de intención emprendedora, se consideran ...
    • Clinical features and prognostic factors of meningococcal disease: A case series study in Chile during the ... 
      Matute, Isabel; Olea, Andrea; López, Darío; Loayza, Sergio; Nájera, Manuel; Arenas González, Claudia; Poffald, Lucy; Hirmas, Macarena; Delgado, Iris; Pedroni, Elena; Alfaro, Tania; Gormaz, Ana María; Sanhueza, Gabriel; Vial, Pablo; Dabanch, Jeannette; Gallegos, Doris; Aguilera, (Sociedad Chilena de Infectologia, 2015)
      © 2015, Sociedad Chilena de Infectologia. All rights reserved.Introduction: Meningococcal disease (MD) is a major global problem because of its case fatality rate and sequels. Since 2012 cases of serogroup W have increased ...
    • Nephronia in pediatrics: Part of the spectrum of upper urinary tract infections. clinical cases and review ... 
      Piñera M., Cecilia; Loyola, Francisca; Hernández, Pamela (Sociedad Chilena de Infectologia, 2015)
      © 2015, Sociedad Chilena de Infectologia. All rights reserved.Nephronia or focal acute nephritis corresponds to a localized inflammatory non-liquefactive kidney infection which may involve parenchyma of one or more renal ...
    • Cabinet turnover and survival of ministers in Chile during the concertación governments (1990-2010) Cambios ... 
      González-Bustamante, Bastián; Olivares, Alejandro (Universidad de los Andes, Bogota Colombia, 2016)
      This article analyzes cabinet turnover and factors that had an influence on the survival of 180 ministers in Chile between 1990 and 2010. With survival analysis, specifically, proportional hazards models and Cox regressions ...
    • Macrophage Recruitment Contributes to Regeneration of Mechanosensory Hair Cells in the Zebrafish Lateral Line 
      Carrillo, Simón A.; Anguita Salinas, Consuelo; Peña, Oscar A.; Morales, Rodrigo A.; Muñoz Sánchez, Salomé; Muñoz Montecinos, Carlos Humberto.; Paredes Zúñiga, Susana; Tapia, Karina; Allende Connelly, Miguel (2016)
      © 2016 Wiley Periodicals, Inc. In vertebrates, damage to mechanosensory hair cells elicits an inflammatory response, including rapid recruitment of macrophages and neutrophils. While hair cells in amniotes usually become ...
    • Humoral and intestinal immunity induced by new schedules of bivalent oral poliovirus vaccine and one or two ... 
      Asturias, Edwin J.; Bandyopadhyay, Ananda S.; Self, Steve; Rivera, Luis; Sáez Llorens, Xavier; Lopez, Eduardo; Melgar, Mario; Gaensbauer, James T.; Weldon, William C.; Oberste, M. Steven; Borate, Bhavesh R.; Gast, Chris; Clemens, Ralf; Orenstein, Walter; O'Ryan Gallardo, Miguel (Lancet Publishing Group, 2016)
      © 2016 Elsevier Ltd Background Replacement of the trivalent oral poliovirus vaccine (tOPV) with bivalent types 1 and 3 oral poliovirus vaccine (bOPV) and global introduction of inactivated poliovirus vaccine (IPV) are major ...
    • Endoplasmic Reticulum Stress and the Hallmarks of Cancer 
      Urra, Hery; Dufey, Estefanie; Avril, Tony; Chevet, Eric; Hetz Flores, Claudio (Cell Press, 2016)
      © 2016 Elsevier Inc. Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic reticulum (ER) stress. To cope with this, cells evoke an adaptive mechanism ...
    • Different Array CGH profiles within hereditary breast cancer tumors associated to BRCA1 expression and ... 
      Alvarez, Carolina; Aravena, Andrés; Tapia, Teresa; Rozenblum, Ester; Solís, Luisa; Corvalán, Alejandro; Camus, Mauricio; Acevedo Alvarez, Manuel; Munroe, David; Maass Sepúlveda, Alejandro; Carvallo, Pilar (BioMed Central Ltd., 2016)
      © 2016 Alvarez et al.Background: Array CGH analysis of breast tumors has contributed to the identification of different genomic profiles in these tumors. Loss of DNA repair by BRCA1 functional deficiency in breast cancer ...