Now showing items 40641-40660 of 101786

    • Muñoz, Matías I.; Penna Varela, Mario (Springer Verlag, 2016)
      © 2016, Springer-Verlag Berlin Heidelberg.Animals relying on acoustic signals for communication must cope with the constraints imposed by the environment for sound propagation. A resource to improve signal broadcast is the ...
    • Alvarez, Carolina; Aravena, Andrés; Tapia, Teresa; Rozenblum, Ester; Solís, Luisa; Corvalán, Alejandro; Camus, Mauricio; Acevedo Alvarez, Manuel; Munroe, David; Maass Sepúlveda, Alejandro; Carvallo, Pilar (BioMed Central Ltd., 2016)
      © 2016 Alvarez et al.Background: Array CGH analysis of breast tumors has contributed to the identification of different genomic profiles in these tumors. Loss of DNA repair by BRCA1 functional deficiency in breast cancer ...
    • Valenzuela, Vicente; Martínez, Gabriela; Durán Aniotz, Claudia; Hetz Flores, Claudio (Elsevier B.V., 2016)
      © 2016 Elsevier B.V. Gene therapy based on the use of Adeno-associated viruses (AAVs) is emerging as a safe and stable strategy to target molecular pathways involved in a variety of brain diseases. Endoplasmic reticulum ...
    • Yoo, Dae Hyun; Prodanovic, Nenad; Jaworski, Janusz; Miranda, Pedro; Ramiterre, Edgar; Lanzon, Allan; Baranauskaite, Asta; Wiland, Piotr; Abud-Mendoza, Carlos; Oparanov, Boycho; Smiyan, Svitlana; Kim, Houng; Lee, Sang Joon; Kim, Suyeon; Park, Won (BMJ Publishing Group, 2017)
      © 2017 Published by the BMJ Publishing Group Limited.Objectives To assess the efficacy and safety of switching from the infliximab reference product (RP; Remicade) to its biosimilar CT-P13 (Remsima, Inflectra) or continuing ...
    • Pérez-Núñez, Ramón; Barraza, Natalia; Gonzalez-Jamett, Arlek; Cárdenas, Ana María; Barnier, Jean Vianney; Caviedes, Pablo (Springer New York LLC, 2016)
      © 2016, Springer Science+Business Media New York.In humans, Down syndrome (DS) is caused by the presence of an extra copy of autosome 21. The most striking finding in DS patients is intellectual disability and the onset ...
    • Fuentes, Aler D.; Sforza, Chiarella; Miralles, Rodolfo; Ferreira, Cláudia L.; Mapelli, Andrea; Lodetti, Gianluigi; Martin, Conchita (Taylor and Francis Ltd., 2017)
      © 2016 Informa UK Limited, trading as Taylor & Francis Group. Objectives: The aim of this study was to investigate whether the presence of a natural mediotrusive contact influences electromyographic (EMG) pattern activity ...
    • Ahumada Galleguillos, Patricio; Lemus, Carmen G.; Díaz, Eugenia; Osorio-Reich, María; Härtel, Steffen; Concha Nordemann, Miguel (Springer Verlag, 2017)
      © 2016, Springer-Verlag Berlin Heidelberg.Brain asymmetry is a conserved feature in vertebrates. The dorsal diencephalic habenular complex shows conspicuous structural and functional asymmetries in a wide range of species, ...
    • Roa, Ignacio; Cantín, Mario; Muñoz, Mariela; Rosas, Carlos; Lemus, David (Universidad de la Frontera, 2016)
      © 2016, Universidad de la Frontera. All rights reserved.Angiogenesis and metastasis are critical events on the tumor invasion process. Their close association is related as a good target in antitumor therapy. The aimwas ...
    • Pellón, Mario; Rojas, Mariana; Saint-Pierre, Gustavo; Hartley, Ricardo; Del Sol, Mariano (Universidad de la Frontera, 2016)
      © 2016, Universidad de la Frontera. All rights reserved. It has been demonstrated that hypoxia retards the growth of fish, reduces the survival of their larvae, deforms their vertebral column, but despite this teleost fish ...
    • Valenzuela, Vicente; Oñate, Maritza; Hetz Flores, Claudio; Court, Felipe A. (Elsevier B.V., 2016)
      © 2016 Elsevier B.V.Injury to the central or peripheral nervous systems leads to the loss of cognitive and/or sensorimotor capabilities that still lack an effective treatment. Although injury to the nervous system involves ...
    • Esquerré, Damien; Troncoso Palacios, Jaime; Barros, Rodrigo (Centro de Referencia em Informacao Ambiental, 2016)
      © 2016 Check List and Authors. Liolaemus riodamas is a recently described lizard, only known from a very restricted river canyon in the Andes of the O’Higgins Region in Chile. The species is particular for being one of the ...
    • Park, Won; Yoo, Dae Hyun; Miranda, Pedro; Brzosko, Marek; Wiland, Piotr; Gutierrez-Ureña, Sergio; Mikazane, Helena; Lee, Yeon Ah; Smiyan, Svitlana; Lim, Mie Jin; Kadinov, Vladimir; Abud-Mendoza, Carlos; Kim, Houng; Lee, Sang Joon; Bae, Yunju; Kim, Suyeon; Braun, Jürgen (BMJ Publishing Group, 2017)
      Objectives To investigate the efficacy and safety of switching from infliximab reference product (RP) to its biosimilar or maintaining biosimilar treatment in patients with ankylosing spondylitis (AS). Methods This open-label ...
    • Fernández Urtubia, Belem; Trevigno Bravo, Antonella; Rodríguez Zamora, Natalie; Palma Torres, Chery; Cid Barria, Luis (Sociedad Chilena de Pediatria, 2016)
      © 2015 Sociedad Chilena de Pediatría. Published por Elsevier España. Introduction Despite advances in the treatment of cancer in paediatric patients, 15% of children die from the illness progression in Chile, and pain is ...
    • Morales Valdés, Gonzalo; Alvarado Romero, Tatiana; Zuleta Castro, Rodrigo (Sociedad Chilena de Pediatria, 2016)
      © 2016 Sociedad Chilena de Pediatría. Published by Elsevier España.Paediatric intensive care is a relatively new specialty, with significant technological advances that lead to the prolongation of the dying process. One ...
    • Ruiz-Rudolph, Pablo; Arias, Nelson; Pardo, Sandra; Meyer, Marianne; Mesías, Stephanie; Galleguillos, Claudio; Schiattino, Irene; Gutiérrez, Luis (Elsevier Ltd, 2016)
      © 2016 Elsevier Ltd. Chile suffers significant pollution from large industrial emitters associated with the mining, metal processing, paper production, and energy industries. The aim of this research was to determine whether ...
    • Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Academic Press Inc., 2015)
      © 2014 Elsevier Inc.Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a "hidden malnutrition" because it does not alter ...
    • Martínez, Carolina; Hernández, Marcela; Martínez, Benjamín; Adorno, Daniela (Sociedad Medica de Santiago, 2016)
      © 2016, Sociedad Medica de Santiago. All right reserved.Background: Oral cancer in Chile corresponds approximately to 1.6% of all cancer cases. There are few studies about oral epithelial dysplasia and oral squamous cell ...
    • Diáz-Cárdenas, Claudia; Wong, Carolina; Vargas Catalán, Nelson (Sociedad Chilena de Pediatria, 2016)
      © 2015 Sociedad Chilena de Pediatriá. Published by Elsevier Espanã.Introduction Type 1 diabetes mellitus (T1D) is an important disease in children and adolescent being a major risk factor for early morbidity and mortality. ...
    • Salinas, Judith; Lera Marques, Lydia; González, Carmen Gloria; Vio del Río, Fernando Tomás (Sociedad Medica de Santiago, 2016)
      © 2016, Sociedad Medica de Santiago. All rights reserved.Background: Unhealthy lifestyles and overweight are common among blue collar workers. Aim: To evaluate a nutrition education intervention in construction workers to ...
    • Moscoso J., Felipe; Quera P., Rodrigo (Sociedad Medica de Santiago, 2016)
      © 2016, Sociedad Medica de Santiago. All rights reserved.The prevalence of Celiac disease in the general population is approximately 1% and remains undiagnosed in a significant proportion of individuals. Its clinical ...