Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 40961-40980 of 101786

    • Intasome architecture and chromatin density modulate retroviral integration into nucleosome 
      Benleulmi, Salah S.; Matysiak, Julien; Henríquez, Rodrigo R.; Vaillant, Cédric; Lesbats, Paul; Calmels, Christina; Naughtin, Monica; León, Oscar; Skalka, Anna Marie; Ruff, Marc; Lavigne, Marc; Andreola, Marie Line; Parissi, Vincent (BioMed Central, 2015)
      Background: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by ...
    • Propiedades psicométricas del cuestionario de calidad de vida relacionada con la salud KIDSCREEN-27 en ... 
      Molina González, Temístocles; Montaño Espinoza, Rosa; González Araya, Electra; Sepúlveda P., Rodrigo; Hidalgo-Rasmussen, Carlos; Martínez N., Vania; Molina Cartes, Ramiro; George L., Myriam (Sociedad Médica de Santiago, 2014)
      Background: KIDSCREEN-52, which assesses health related quality of life in adolescents, has been adapted and validated in Chile showing excellent psychometric properties. There is a shorter version of the instrument, ...
    • Obesidad en mujeres chilenas en edad fértil 
      Araya Bannout, Marcela; Padilla, Oslando; Garmendia Miguel, María Luisa; Atalah, Eduardo; Uauy Dagach-Imbarack, Ricardo (Sociedad Médica de Santiago, 2014)
      Background: Women in childbearing ages (WCBA) represent a strategic intervention group to reverse the global trend of increasing obesity. Aim: To conduct a review of studies reporting obesity prevalence in WCBA in Chile ...
    • Impact of living and socioeconomic characteristics on cardiovascular risk in ischemic stroke patients 
      Amarenco, Pierre; Abboud, Halim; Labreuche, Julien; Arauz, Antonio; Bryer, Alan; Lavados Germain, Pablo Manuel; Massaro, Ayrton; Muñoz Collazos, Mario; Steg, Philippe Gabriel; Yamout, Bassem I.; Vicaut, Eric (Blackwell, 2014)
      Objective We aimed to stratify the risk of vascular event recurrence in patients with cerebral infarction according to living and socioeconomic characteristics and geographic region. Method The Outcomes in Patients with ...
    • Ventilatory function and cardiovascular disease risk factors: A cross-sectional study in young adults 
      García Larsen, Vanessa; Bustos, Patricia; Amigo, Hugo; Potts, James; Rona, Roberto J. (BioMed Central, 2014)
      Background: The association between impaired lung function and cardiovascular disease (CVD) risk factors has been shown in adults. However, there is little evidence of such an association in young adults, particularly ...
    • Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas 
      Canals Cifuentes, Andrea; Cavada Chacón, Gabriel; Nazer Herrera, Julio (Sociedad Médica de Santiago, 2014)
      Background: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors ...
    • Hydration status after exercise affect resting metabolic rate and heart rate variability 
      Castro Sepúlveda, Mauricio; Cerda Kohler, Hugo; Pérez Luco, Cristian; Monsalves, Matías; Andrade, David Cristóbal; Zbinden Foncea, Hermann; Báez San Martín, Eduardo; Ramírez Campillo, Rodrigo (Grupo Aula Médica, 2015)
      Introduction: Heart rate variability and resting metabolic rate are commonly to assess athlete´s physiological status and energy requirements. Exercise-induced dehydration can reach up to 5% of body mass per hour. ...
    • Central obesity and not age increases skeletal muscle lipids, without influencing lean body mass and strength 
      Maza Cave, María Pía de la; Hirsch Birn, Sandra; Jara, Natalia; Leiva, Laura; Barrera, Gladys; Silva, Claudio; Pañella, Loreto; Henríquez, Sandra; Bunout Barnett, Daniel (Grupo Aula Médica, 2015)
      Background/Aims: To measure skeletal muscle lipid infiltration, its association with insulin resistance (IR) lean mass and function, in Chilean men differing in age and body composition. Our hypothesis was that muscle ...
    • Glycemic control and oxidative stress markers and their relationship with the thioredoxin interacting protein ... 
      Andrews Guzmán, Mónica; Arredondo Olguín, Miguel; Olivares Gronhert, Manuel (Grupo Aula Médica, 2015)
      Objective: To investigate the relationship between oxidative stress and biochemical parameters and the expression of TXNIP, IL-6, IL-1β and TNF-α in peripheral mononuclear cells (PMCs) from type-2 diabetic patients. Methods: ...
    • Consumption of orange fermented beverage reduces cardiovascular risk factors in healthy mice 
      Escudero López, Blanca; Berná, Genoveva; Ortega, Ángeles; Herrero Martín, Griselda; Cerrillo, Isabel; Martín, Franz; Fernández Pachón, María Soledad (Elsevier, 2015)
      The consumption of fruits prevents the risk of cardiovascular diseases. Alcoholic fermentation has been carried out in fruits resulting in products which provide high concentration of bioactive compounds and variable alcohol ...
    • The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle ... 
      Llanos Vidal, Paola; Contreras Ferrat, Ariel; Georgiev, Tihomir; Osorio Fuentealba, César; Espinosa, Alejandra; Hidalgo, Jorge; Hidalgo Tapia, María Cecilia; Jaimovich Pérez, Enrique (American Physiological Society, 2015)
      Insulin stimulates glucose uptake in adult skeletal muscle by promoting the translocation of GLUT4 glucose transporters to the transverse tubule (T-tubule) membranes, which have particularly high cholesterol levels. We ...
    • Iron overload-modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism ... 
      Alvarado Díaz, Carlos Patricio; Núñez González, Marco; Devoto, Luigi; González Ramos, Reinaldo (Elsevier, 2015)
      Objective: To evaluate the effect of iron overload on nuclear factor kappa-B (NF-kappa B) activation in human endometrial stromal cells (ESCs). Design: Experimental study. Setting: University hospital research ...
    • The effects of hormonal contraceptives on glycemic regulation 
      Cortés, Manuel E.; Alfaro, Andrea A. (Maney Publishing, 2014)
      A number of side effects have been linked to the use of hormonal contraceptives, among others, alterations in glucose levels. Hence, the objective of this mini-review is to show the main effects of hormonal contraceptive ...
    • Intraoperative cystography pre- and post-endoscopic treatment for vesicoureteral reflux: Guaranteed success? 
      López, P. J.; Reed, F.; Ovalle, A.; Celis, S.; Reyes, D.; Letelier, N.; Zubieta, R. (Elsevier, 2014)
      Objective: This study was designed to investigate whether post-endoscopic treatment (ET) intraoperative cystography is predictive of treatment outcome. Patients and methods: Patients diagnosed with vesicoureteral reflux ...
    • Enfermedad meningocóccica en la Región Metropolitana de Chile y su correlación con factores ambientales 
      Bahamonde, Cristian; Stuardo, Valeria; Hott-Harvey, Bárbara; Manríquez, José; Mardones, Pedro (Sociedad Chilena de Infectologia, 2014)
      Introduction: Meningococcal disease (MD) is a public health problem worldwide, due to its high morbidity and mortality. Most cases occur in sub-Saharan Africa, where there is a marked seasonal pattern with predominance during ...
    • Large contribution of human papillomavirus in vaginal neoplastic lesions: A worldwide study in 597 samples 
      Alemany, L.; Saunier, M.; Tinoco, L.; Quirós, B.; Alvarado Cabrero, I.; Alejo, M.; Joura, E. A.; Maldonado, P.; Klaustermeier, J.; Salmerón, J.; Bergeron, C.; Petry, K. U.; Guimerà, N.; Clavero, O.; Murillo, R.; Clavel, C.; Wain, V.; Geraets, D. T.; Jach, R.; Cross, P.; Carrilho, C.; Molina, C.; Shin, H. R.; Mandys, V.; Nowakowski, A. M.; Vidal, A.; Lombardi, L.; Kitchener, H.; Sica, A. R.; Magaña León, C.; Pawlita, M.; Quint, W.; Bravo, I. G.; Muñoz, N.; Sanjosé, S. de; Bosch, F. X. (Elsevier, 2014)
      Aim: This work describes the human papillomavirus (HPV) prevalence and the HPV type distribution in a large series of vaginal intraepithelial neoplasia (VAIN) grades 2/3 and vaginal cancer worldwide. Methods: We analysed ...
    • Detection of serinocarbapenemases class a and other mechanisms of enzymatic resistance to β-lactams in ... 
      de la Lastra, Virginia; Rivas, Lina M.; Silva, Francisco; Ulloa, M. Teresa; Pinto, M. Eugenia; Vidal, Mario (Sociedad Chilena de Infectologia, 2014)
      © 2014, Sociedad Chilena de Infectologia. All rights reserved.Background: The emergence of carbapenemase mediated resistance in Enterobacteriaceae has a strong clinical impact. This study aimed to do a genotypic and ...
    • Probiotic screening and safety evaluation of lactobacillus strains from plants, artisanal goat cheese, human ... 
      Gotteland, Martin; Cires, Maria Jose; Carvallo, Claudia; Vega, Natalia; Ramirez, Maria Antonieta; Morales, Pamela; Rivas, Patricia; Astudillo, Fernanda; Navarrete, Paola; Dubos, Céline; Figueroa, Alvaro; Troncoso, Miriam; Ulloa, Carolina; Mizgier, Maria Luisa; Carrasco Pozo, Catalina; Speisky, Hernan; Brunser, Oscar; Figueroa, Guillermo (Mary Ann Liebert, 2014)
      The aim of this study was to select autochthonous strains of Lactobacillus from stools of healthy infants and adults, human milk, artisanal goat cheese, and fruits and vegetables according to their probiotic properties and ...
    • The Neuroplastin adhesion molecules: Key regulators of neuronal plasticity and synaptic function 
      Beesley, Philip W.; Herrera Molina, Rodrigo; Smalla, Karl-Heinz; Seidenbecher, Constanze (Blackwell, 2014)
      The Neuroplastins Np65 and Np55 are neuronal and synapseenriched immunoglobulin superfamily molecules that play important roles in a number of key neuronal and synaptic functions including, for Np65, cell adhesion. In ...
    • Deficiency in mannose-binding lectin-associated serine protease-2 does not increase susceptibility to ... 
      Ribeiro, Carolina H.; Lynch, Nicholas J.; Stover, Cordula M.; Ali, Youssif M.; Valck, Carolina; Noya-Leal, Francisca; Schwaeble, Wilhelm J.; Ferreira, Arturo (American Society of Tropical Medicine and Hygiene, 2015)
      Trypanosoma cruzi is the causative agent of Chagas’ disease, a chronic illness affecting 10 million people around the world. The complement system plays an important role in fighting microbial infections. The recognitio ...