Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 2821-2840 of 4850

    • Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and ... 
      Hahn, Wendy S.; Kuzmicic Previtali, Jovan Paolo; Burrill, Joel S.; Donoghue, Margaret A.; Foncea, Rocío; Jensen, Michael D.; Lavandero González, Sergio; Arriaga, Edgar A.; Bernlohr, David A. (American Physiological Society, 2014)
      Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. Macrophage infiltration of adipose tissue and the chronic low-grade production of inflammatory cytokines ...
    • Detecting Ni(II) in aqueous solution by3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyridine anddimethyl- -cyclodextrin 
      Jullian Matthaei, Carolina; Fernández Sandoval, Samuel; Rojas Aranguiz, Max; Gómez Machuca, Horacio Exequiel; Salgado-Figueroa, Paola; Celis-Barros, Cristián; Zapata-Torres, Gerald; Adam, Rosa; Abarca, Belén (Elsevier, 2014)
      A new supramolecular sensitizer for nickel(II) ion in aqueous solution based on a pyridyltriazolopyridine-cyclodextrin inclusion complex is proposed. The inclusion complexation behavior, characterization andbinding ability ...
    • Sensing immobilized molecules of streptavidin on a silicon surface by maldi-tof mass spectrometry and ... 
      Araya, Eyleen; Kogan Bocian, Marcelo; Guell, Aleix G.; Escobar, Carlos A.; Sanz, Fausto (2014)
      A hydrogen-terminated Si (111) surface was modified to form an aminoterminated monolayer for immobilization of streptavidin. Cleavage of an N-(ω- undecylenyl)-phthalimide covered surface using hidrazine yields an amino ...
    • Quantum dot-based assay for Cu2+ quantification in bacterial cell culture 
      Durán Toro, V.; Gran Scheuch, A.; Órdenes Aenishanslins, N.; Monrás, J. P.; Saona, L. A.; Venegas, F. A.; Chasteen, T. G.; Bravo, D.; Pérez Donoso, José (Elsevier, 2014)
      A simple and sensitive method for quantification of nanomolar copper with a detection limit of 1.2 x 10-10 M and a linear range from 10-9 to 10-8 M is reported. For the most useful analytical concentration of quantum ...
    • Contribution of metals, sulfur-dioxide and phenolic compounds to the antioxidant capacity of Carménère wines 
      Zúñiga, María A.; Pérez Roa, Rodolfo E.; Olea Azar, Claudio; Laurie, V. Felipe; Agosin Trumper, Eduardo (Elsevier, 2014)
      In this research, we determined the chemical composition of 37 Vitis vinifera cv. Carme´ne` re wines and established their antioxidant capacity (AC). A set of 26 measurements of chemical species potentially related to ...
    • Physico-chemical characterization of ferrocenyl-modified hyperbranched poly(ethylenimine) self-assembled ... 
      Bracamonte, María V.; Yáñez Soto, Claudia; Bollo Dragnic, Soledad; Rivas, Gustavo A.; Ferreyra, Nancy F. (Elsevier, 2014)
      In this work, we characterize the electrochemical behavior of a new ferrocenyl-modified, hyperbranched poly(ethylenimine) (HBPei-Fc). The effects of the ionic strength, pH and the nature of the anion of the supporting ...
    • Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume ... 
      Escobar Oregón, Leslie Dominique; Andresen, Max; Downey, Patricio; Gai Hernández, María Nella; Regueira, Tomás; Bórquez, Tamara; Lipman, Jeffrey; Roberts, Jason A. (Elsevier, 2014)
      This study aimed to describe the population pharmacokinetics of vancomycin in critically ill patients with refractory septic shock undergoing continuous venovenous high-volume haemofiltration (HVHF) and to define appropriate ...
    • Comparison of the total phenolic content, total anthocyanin content and antioxidant activity of polyphenol-rich ... 
      Fredes González, Carolina; Montenegro, Gloria; Zoffoli, Juan Pablo; Santander, Francisca; Robert Canales, Paz (Ciencia e Investigación Agraria, 2014)
      In the last 10 years, interest in research on polyphenol-rich fruit species has increased due to the potential health benefits of these species, mainly attributed to their high anthocyanin content and antioxidant activity. ...
    • Organelle communication: Signaling crossroads between homeostasis and disease 
      Bravo Sagua, Roberto; Torrealba Cárdenas, Natalia Belén; Paredes, Felipe; Morales, Pablo E.; Pennanen Saavedra, Christian; López Crisosto, Camila; Troncoso Cotal, Rodrigo; Criollo Céspedes, Alfredo; Chiong Lay, Mario; Hill, Joseph A.; Simmend, Thomas; Quest, Andrew F. G.; Lavandero González, Sergio (Elsevier, 2014)
      Cellular organelles do not function as isolated or static units, but rather form dynamic contacts between one another that can be modulated according to cellular needs. The physical interfaces between organelles are ...
    • Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is ... 
      Pezoa, David; Blondel Buijuy, Carlos José; Silva Valenzuela, Cecilia Alejandra; Yang, Hee-Jeong; Andrews Polymenis, Helene; Santiviago Cid, Carlos; Contreras, Inés (BioMed Central, 2014)
      The type VI secretion system (T6SS) is a virulence factor for many Gram-negative bacteria. Salmonella genus harbors five phylogenetically distinct T6SS loci encoded in Salmonella Pathogenicity Islands (SPIs) SPI-6, SPI-19, ...
    • Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. 
      Rojas, P. S.; Neira, D.; Muñoz, Mauricio; Lavandero González, Sergio; Fiedler Temer, Jenny (Wiley, 2014)
      Serotonin (5-HT) production and expression of 5-HT receptors (5-HTRs) occur early during prenatal development. Recent evidence suggests that, in addition to its classical role as a neurotransmitter, 5-HT regulates neuronal ...
    • Novel Aspects of Glucocorticoid Actions 
      Uchoa, E. T.; Aguilera, G.; Herman, J. P.; Fiedler Temer, Jenny; Deak, T.; De Sousa, M. B. C. (British Society for Neuroendocrinology, 2014)
      Normal hypothalamic-pituitary-adrenal (HPA) axis activity leading to the rhythmic and episodic release of adrenal glucocorticoids (GCs) is essential for body homeostasis and survival during stress. Acting through specific ...
    • Synthesis and electrochemical oxidation of hybrid compounds:dihydropyridine-fused coumarins 
      Pardo Jiménez, Viviana Gladys; Barrientos, C.; Pérez Cruz, Karina Angélica; Navarrete Encina, Patricio; Olea Azar, Claudio; Núñez Vergara, Luis; Squella Serrano, Juan (Elsevier, 2013)
      tIn this paper, a series of six dihydropyridine-fused coumarins were synthesized and electrochemicallycharacterized in dimethylformamide (DMF).Dihydropyridine ring oxidation on glassy carbon electrode (GCE) for condensed ...
    • NMR and molecular fluorescence spectroscopic study of the structure and thermodynamic parameters of EGCG/ ... 
      Folch Cano, Christian; Guerrero, Juan; Speisky Cosoy, Hernán; Jullian Matthaei, Carolina; Olea Azar, Claudio (Springer, 2013)
      The present study is focused on the characterization of the interaction between (-)-epigallocatechingallate (EGCG) and cyclodextrins like b-cyclodextrin (bCD), heptakis(2,6 di-O-methyl)-b-cyclodextrin (DMbCD), ...
    • New insights into IGF-1 signaling in the heart 
      Troncoso Cotal, Rodrigo Hernán; Ibarra, Cristián; Vicencio, José Miguel; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2014)
      Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy, autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an increased risk of cardiovascul ...
    • El análisis sensorial en el desarrollo y evaluación de nuevos productos para regímenes especiales 
      Wittig de Penna, Emma (Universidad de Chile, 2000)
    • Neuroendocrine Regulation and Homeostasis 
      Mani, Shaila K.; Anselmo-Franci, Janete; Lara Peñaloza, Hernán; Suchecki, Deborah; Poletini, Maristela O.; Handa, Robert J.; John Wu, Tao-yiao (British Society for Neuroendocrinology, 2014)
    • Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through ... 
      Campo Sfeir, Andrea Estefanía del; Parra Ortíz, María Valentina; Vásquez Trincado, César Alonso; Gutiérrez, Tomás; Morales, Pablo E.; López Crisosto, Camila; Bravo Sagua, Roberto; Navarro Márquez, Mario F.; Verdejo, Hugo E.; Contreras Ferrat, Ariel Eduardo; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Lavandero González, Sergio (American Physiological Society, 2014)
      Insulin is a major regulator of glucose metabolism, stimulating its mitochondrial oxidation in skeletal muscle cells. Mitochondria are dynamic organelles that can undergo structural remodeling in order to cope with these ...
    • Antibacterial, kinetics and bacteriolytic properties of silver(I) pyridinedicarboxylate compounds 
      Azócar, M. Ignacio; Gómez, Grace; Velásquez, Carla; Abarca, Romina; Kogan Bocian, Marcelo; Páez, Maritza (Elsevier, 2014)
      Antibacterial properties of silver(I)-pyridinedicarboxylate compounds (with Pyridine-2,3-dicarboxylic(Lutidinic acid), pyridine-2,4-dicarboxylic (Quinolinic acid) and pyridine-2,5-dicarboxylic (Isocinchomeronic acid)) ...
    • Microencapsulation of pulp and ultrafiltered cactus pear (Opuntia ficus-indica) extracts and betanin stability ... 
      Vergara Hinostroza, Cristina; Saavedra, Jorge; Sáenz Hernández, Carmen Luisa; García, Paula; Robert Canales, Paz (Elsevier, 2014)
      Pulp (CP) and ultrafiltered (UF) cactus pear extracts were encapsulated with Capsul (C) by applying a central composite design (CP–C and UF–C systems) by spray-drying. To evaluate the effect of the extract, microparticles ...