Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 3061-3080 of 5098

    • Stress and the Reproductive Axis 
      Toufexis, D.; Rivarola, M. A.; Lara Peñaloza, Hernán; Viau, V. (British Society for Neuroendocrinology, 2014)
      There exists a reciprocal relationship between the hypothalamic-pituitary-adrenal (HPA) and the hypothalamic-pituitary-gonadal (HPG) axes, wherein the activation of one affects the function of the other and vice versa. ...
    • Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway 
      Wang, Zhao V.; Deng, Yingfeng; Gao, Ningguo; Pedrozo Cibils, Zully; Li, Dan L.; Morales, Cyndi R.; Criollo Céspedes, Alfredo; Luo, Xiang; Tan, Wei; Jiang, Nan; Lehrman, Mark A.; Rothermel, Beverly A.; Lee, Ann Hwee; Lavandero González, Sergio; Mammen, Pradeep P .A.; Ferdous, Anwarul; Gillette, Thomas G.; Scherer, Philipp E.; Hill, Joseph A. (Elsevier, 2014-03-13)
      The hexosamine biosynthetic pathway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) for glycan synthesis and O-linked GlcNAc (O-GlcNAc) protein modifications. Despite the established role of the ...
    • Spectral and Kinetic Properties of Radical Cations Derived from Oxoisoaporphines: Relevance to Electron-Transfer ... 
      Fuente Urrutia, Julio de la; Kciuk, Gabriel; Aliaga Silva, Christian Marcelo; Bobrowski, Krzysztof (American Chemical Society, 2014)
      The thermally induced intermolecular electron transfer reaction in acetonitrile between the tetracyanoethylene (TCNE), a [pi]-electron acceptor with a large electron affinity, and six oxoisoaporphines (2,3-dihydro-7H-d ...
    • Enfermedad de chagas, biotransformación de xenobióticos por el trypanosama cruzi 
      Morello Casté, Antonio; Letelier, María Eugenia; Aldunate, Jorge; Repetto Scaramelli, Yolanda (Universidad de Chile, 1987)
    • Rotating-disk sorptive extraction: effect of the rotation mode of the extraction device on mass transfer efficiency 
      Jachero, Lourdes; Ahumada Torres, Aída Inés de Lourdes; Richter Duk, Pablo (Springer-Verlag, 2014)
      The extraction device used in rotating-disk sorptive extraction consists of a Teflon disk in which a sorptive phase is fixed on one of its surfaces. Depending on the configuration, the rotation axis of the disk device ...
    • Effect of biosolid application to Mollisol Chilean soils on the bioavailability of heavy metals (Cu, Cr, ... 
      Ahumada Torres, Aída Inés de Lourdes; Sepúlveda, Karen; Fernández, Priscilla; Ascar Estay, María Loreto; Pedraza, Cristina; Richter Duk, Pablo; Brown, Sally (Springer, 2014)
      Purpose This study assessed the effect of biosolid application on the bioavailable fraction of some trace elements (Cu, Cr, Ni, and Zn) using a bioassay with sunflower (Helianthus annuus) and a chemical assay, diffusion ...
    • Dopamine in human follicular fluid is associated with cellular uptake and metabolism-dependent generation ... 
      Saller, Sabine; Kunz, L.; Berg, D.; Berg, U.; Lara Peñaloza, Hernán; Urra, J.; Hecht, S.; Pavlik, R.; Thaler, C.J.; Mayerhofer, A. (Oxford University Press, 2014)
      studyquestion: Is the neurotransmitter dopamine (DA) in the human ovary involved in the generation of reactive oxygen species (ROS)? summary answer: Human ovarian follicular fluid contains DA, which causes the generation ...
    • Defined Single-Gene and Multi-Gene Deletion Mutant Collections in Salmonella enterica sv Typhimurium 
      Porwollik, Steffen; Santiviago Cid, Carlos; Cheng, Pui; Long, Fred; Desai, Prerak; Fredlund, Jennifer; Srikumar, Shabarinath; Silva, Cecilia A.; Chu, Weiping; Chen, Xin; Canals, Rocío; Reynolds, M. Megan; Bogomolnaya, Lydia; Shields, Christine; Cui, Ping; Guo, Jinbai; Zheng, Yi; Endicott Yazdani, Tiana; Yang, Hee-Jeong; Maple, Aimee; Ragoza, Yury; Blondel, Carlos J.; Valenzuela, Camila; Andrews Polymenis, Helene; McClelland, Michael (PLOS One, 2014)
      We constructed two collections of targeted single gene deletion (SGD) mutants and two collections of targeted multi-gene deletion (MGD) mutants in Salmonella enterica sv Typhimurium 14028s. The SGD mutant collections ...
    • Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and ... 
      Hahn, Wendy S.; Kuzmicic Previtali, Jovan Paolo; Burrill, Joel S.; Donoghue, Margaret A.; Foncea, Rocío; Jensen, Michael D.; Lavandero González, Sergio; Arriaga, Edgar A.; Bernlohr, David A. (American Physiological Society, 2014)
      Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. Macrophage infiltration of adipose tissue and the chronic low-grade production of inflammatory cytokines ...
    • Detecting Ni(II) in aqueous solution by3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyridine anddimethyl- -cyclodextrin 
      Jullian Matthaei, Carolina; Fernández Sandoval, Samuel; Rojas Aranguiz, Max; Gómez Machuca, Horacio Exequiel; Salgado-Figueroa, Paola; Celis-Barros, Cristián; Zapata-Torres, Gerald; Adam, Rosa; Abarca, Belén (Elsevier, 2014)
      A new supramolecular sensitizer for nickel(II) ion in aqueous solution based on a pyridyltriazolopyridine-cyclodextrin inclusion complex is proposed. The inclusion complexation behavior, characterization andbinding ability ...
    • Sensing immobilized molecules of streptavidin on a silicon surface by maldi-tof mass spectrometry and ... 
      Araya, Eyleen; Kogan Bocian, Marcelo; Guell, Aleix G.; Escobar, Carlos A.; Sanz, Fausto (2014)
      A hydrogen-terminated Si (111) surface was modified to form an aminoterminated monolayer for immobilization of streptavidin. Cleavage of an N-(ω- undecylenyl)-phthalimide covered surface using hidrazine yields an amino ...
    • Quantum dot-based assay for Cu2+ quantification in bacterial cell culture 
      Durán Toro, V.; Gran Scheuch, A.; Órdenes Aenishanslins, N.; Monrás, J. P.; Saona, L. A.; Venegas, F. A.; Chasteen, T. G.; Bravo, D.; Pérez Donoso, José (Elsevier, 2014)
      A simple and sensitive method for quantification of nanomolar copper with a detection limit of 1.2 x 10-10 M and a linear range from 10-9 to 10-8 M is reported. For the most useful analytical concentration of quantum ...
    • Contribution of metals, sulfur-dioxide and phenolic compounds to the antioxidant capacity of Carménère wines 
      Zúñiga, María A.; Pérez Roa, Rodolfo E.; Olea Azar, Claudio; Laurie, V. Felipe; Agosin Trumper, Eduardo (Elsevier, 2014)
      In this research, we determined the chemical composition of 37 Vitis vinifera cv. Carme´ne` re wines and established their antioxidant capacity (AC). A set of 26 measurements of chemical species potentially related to ...
    • Physico-chemical characterization of ferrocenyl-modified hyperbranched poly(ethylenimine) self-assembled ... 
      Bracamonte, María V.; Yáñez Soto, Claudia; Bollo Dragnic, Soledad; Rivas, Gustavo A.; Ferreyra, Nancy F. (Elsevier, 2014)
      In this work, we characterize the electrochemical behavior of a new ferrocenyl-modified, hyperbranched poly(ethylenimine) (HBPei-Fc). The effects of the ionic strength, pH and the nature of the anion of the supporting ...
    • Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume ... 
      Escobar Oregón, Leslie Dominique; Andresen, Max; Downey, Patricio; Gai Hernández, María Nella; Regueira, Tomás; Bórquez, Tamara; Lipman, Jeffrey; Roberts, Jason A. (Elsevier, 2014)
      This study aimed to describe the population pharmacokinetics of vancomycin in critically ill patients with refractory septic shock undergoing continuous venovenous high-volume haemofiltration (HVHF) and to define appropriate ...
    • Comparison of the total phenolic content, total anthocyanin content and antioxidant activity of polyphenol-rich ... 
      Fredes González, Carolina; Montenegro, Gloria; Zoffoli, Juan Pablo; Santander, Francisca; Robert Canales, Paz (Ciencia e Investigación Agraria, 2014)
      In the last 10 years, interest in research on polyphenol-rich fruit species has increased due to the potential health benefits of these species, mainly attributed to their high anthocyanin content and antioxidant activity. ...
    • Organelle communication: Signaling crossroads between homeostasis and disease 
      Bravo Sagua, Roberto; Torrealba Cárdenas, Natalia Belén; Paredes, Felipe; Morales, Pablo E.; Pennanen Saavedra, Christian; López Crisosto, Camila; Troncoso Cotal, Rodrigo; Criollo Céspedes, Alfredo; Chiong Lay, Mario; Hill, Joseph A.; Simmend, Thomas; Quest, Andrew F. G.; Lavandero González, Sergio (Elsevier, 2014)
      Cellular organelles do not function as isolated or static units, but rather form dynamic contacts between one another that can be modulated according to cellular needs. The physical interfaces between organelles are ...
    • Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is ... 
      Pezoa, David; Blondel Buijuy, Carlos José; Silva Valenzuela, Cecilia Alejandra; Yang, Hee-Jeong; Andrews Polymenis, Helene; Santiviago Cid, Carlos; Contreras, Inés (BioMed Central, 2014)
      The type VI secretion system (T6SS) is a virulence factor for many Gram-negative bacteria. Salmonella genus harbors five phylogenetically distinct T6SS loci encoded in Salmonella Pathogenicity Islands (SPIs) SPI-6, SPI-19, ...
    • Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. 
      Rojas, P. S.; Neira, D.; Muñoz, Mauricio; Lavandero González, Sergio; Fiedler Temer, Jenny (Wiley, 2014)
      Serotonin (5-HT) production and expression of 5-HT receptors (5-HTRs) occur early during prenatal development. Recent evidence suggests that, in addition to its classical role as a neurotransmitter, 5-HT regulates neuronal ...
    • Novel Aspects of Glucocorticoid Actions 
      Uchoa, E. T.; Aguilera, G.; Herman, J. P.; Fiedler Temer, Jenny; Deak, T.; De Sousa, M. B. C. (British Society for Neuroendocrinology, 2014)
      Normal hypothalamic-pituitary-adrenal (HPA) axis activity leading to the rhythmic and episodic release of adrenal glucocorticoids (GCs) is essential for body homeostasis and survival during stress. Acting through specific ...