Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 3081-3100 of 4942

    • Preliminary evaluation of DNA damage related with the smoking habit measured by the comet assay in whole ... 
      Pérez Alzola, Luz Patricia; Farfán Urzúa, Mauricio Javier; González Hormazábal, Patricio; Garay, Marta; Olmedo, María Isabel; Ellahueñe Manquian, Manuel; Last, Jerold A. (2004-07)
      The alkaline single-cell gel electrophoresis (SCGE) assay, also called the comet assay, is a rapid and simple method for the detection of DNA damage in individual cells. The objective of this study was to establish if ...
    • Photoreduction of Azaoxoisoaporphines by Amines: Laser Flash and Steady-State Photolysis and Pulse Radiolysis ... 
      Fuente, Julio R. de la; Aliaga, Christian; Cañete, Alvaro; Kciuk, Gabriel; Szreder, Tomasz; Bobrowski, Krzysztof (The American Society of Photobiology, 2013)
      Photoreduction of 7H-benzo[e]perimidin-7-one (3-AOIA, A1) and its 2-methyl derivative (2-Me-3-AOIA, A2) by non-Hdonating amines (1,4-diazabicyclo[2.2.2]octane [DABCO]; 2,2,6,6-tetramethylpiperidine [TMP]), and a ...
    • Organometallic Schiff bases derived from 5-nitrothiophene and 5-nitrofurane: Synthesis, crystallographic, ... 
      Arancibia, Rodrigo; Klahn, A. Hugo; Buono Core, Gonzalo E.; Contreras, Daniel; Barriga, Germán; Olea Azar, Claudio; Lapier, Michel; Maya Arango, Juan; Ibañez, Andrés; Garland, María Teresa (Elsevier, 2013)
      In the search for new therapeutic tools for the treatment of American trypanosomiasis, a series of novel ferrocene and cyrhetrene imine compounds, derived from 5-nitro-heterocycles, were designed, synthesized and ...
    • Solubilization of lipid bilayers by myristyl sucrose ester: effect of cholesterol and phospholipid head group size 
      Toro, C.; Sánchez, S. A.; Zanocco Loyola, Antonio; Lemp Miranda, Else; Gratton, E.; Gunthera, G. (Elsevier, 2009-02)
      The solubilization of biological membranes by detergents has been used as amajor method for the isolation and purification of membrane proteins and other constituents. Considerable interest in this field has resulted ...
    • Genetic composition of Mytilus species in mussel populations from southern Chile 
      Larraín Barth, María Angélica; Díaz Pérez, Nelson; Lamas, Carmen; Vargas, Carlos; Araneda Tolosa, Cristian (2012)
      Mussels are one of the most cultivated and commercialized bivalves worldwide and in southern Chile its culture represent an important economic activity. The species identification within the Mytilus genera, by morphological ...
    • Occupancy Distributions Arising in Sampling from Gibbs-Poisson Abundance Models 
      Huillet, Thierry; Martínez Aguilera, Servet (Springer, 2013)
      Estimating the number n of unseen species from a k-sample displaying only p ≤ k distinct sampled species has received attention for long. It requires a model of species abundance together with a sampling model. We start ...
    • Naphthoxazole-Based Singlet Oxygen Fluorescent Probes 
      Ruiz González, Rubén; Zanocco, Renzo P.; Gidi, Yasser; Zanocco Loyola, Antonio; Nonell, Santi; Lemp Miranda, Else (The American Society of Photobiology, 2013)
      In this study, we report the synthesis and photochemical behavior of a new family of photoactive compounds to assess its potential as singlet oxygen (1O2) probes. The candidate dyads are composed by a 1O2 trap plus a ...
    • Studies on ATP - diphosphohydrolase nucleotide-binding sites by intrinsic fluorescence 
      Kettlun Leyton, Andrés; Espinosa, V.; Zanocco Loyola, Antonio; Valenzuela Pedevila, María Antonieta (2000-07)
      Potato apyrase, a soluble ATP-diphosphohydrolase, was purified to homogeneity from several clonal varieties of Solanum tuberosum. Depending on the source of the enzyme, differences in kinetic and physicochemical properties ...
    • Sucrose Monoester Micelles Size Determined by Fluorescence Correlation Spectroscopy (FCS) 
      Sánchez, Susana A.; Gratton, Enrico; Zanocco Loyola, Antonio; Lemp Miranda, Else; Günther Sapunar, Germán (PUBLIC LIBRARY SCIENCE, 2011-12-28)
      One of the several uses of sucrose detergents, as well as other micelle forming detergents, is the solubilization of different membrane proteins. Accurate knowledge of the micelle properties, including size and shape, are ...
    • Bromide/Chtoride Counterion Exchange at the Surfaces of Dioctadecytdlmethylammonium Vesicles 
      Liss, Eduardo A.; Abuin, E. B.; Zanocco Loyola, Antonio; Backer, C. A.; Whitten, D. G. (American Chemical Society, 1989)
      The exchange between bromide and chloride counterions at the surfaces of dioctadecyldimethylammonium vesicles has been examined through fluorescence quenching experiments. The quenching of the fluorescence of vesicle-incorporated ...
    • Anomalous Dependence of Pyrene Spectra and Lifetimes with Temperature in Large Unilamellar Vesicles from ... 
      Lissi Gervaso, Eduardo A.; Abuin, Elsa; Sáez, M.; Zanocco Loyola, Antonio; Disalvo, A. (American Chemical Society, 1992-08)
      Lifetimes of pyrene incorporated into large unilamellar vesicles of dipalmitoylphosphatidylcholine and dioctadecyldimethylammonium chloride increase when the temperature increases prior to the melting temperature of the ...
    • EPAC expression and function in cardiac fibroblasts and myofibroblasts 
      Olmedo, Ivonne; Muñoz, Claudia; Guzmán, Nancy; Catalán, Mabel; Vivar, Raúl; Ayala, Pedro; Humeres Martínez, Claudio; Aránguiz, Pablo; García Nannig, Lorena; Velarde, Victoria; Díaz Araya, Guillermo (Elsevier, 2013)
      In the heart, cardiac fibroblasts (CF) and cardiac myofibroblasts (CMF) are the main cells responsible for wound healing after cardiac insult. Exchange protein activated by cAMP (EPAC) is a downstream effector of cAMP, ...
    • DNA, Cell Wall and General Oxidative Damage Underlie the Tellurite/Cefotaxime Synergistic Effect in Escherichia ... 
      Molina Quiroz, Roberto C.; Loyola, David E.; Muñoz Villagrán, Claudia; Quatrini, Raquel; Vásquez, Claudio C.; Pérez Donoso, José (PLoS ONE 8(11): e79499, 2013)
      The constant emergence of antibiotic multi-resistant pathogens is a concern worldwide. An alternative for bacterial treatment using nM concentrations of tellurite was recently proposed to boost antibiotic-toxicity and a ...
    • Bis(3,5-dibromo-N-o-tolylsalicylaldiminato)copper(ll) 
      Manríquez Castro, Víctor; Costamagna, J.; Vargas, J.; Von Schnering, H. G.; Paters, K. (1990-01-30)
      [Cu(C~4H~oBr2NO)2], Mr=799.6, monoclinic, P2~/n, a=17.866(5), b=21-963(6), c = 14.128 (4) A, ,8 = 93"16 (2) ° V = 5535 (2) A 3, Z= 8, Dx =l'919Mgm -3, /z=6.54mm -~, A(MoKa) = 0-71069 A, F(000) = 3096, T= 293 K, final R ...
    • New quaternary alkali metal, rare earth (3+) thiophosphate, K2SmP2S7 with both [P2S6]4 and [PS4]3 anions 
      Manríquez Castro, Víctor; Galdámez Silva, Antonio; Guzmán Águila, Daniela (Elsevier, 2008)
      A new quaternary alkali metal, rare earth thiophosphate was synthesized by the ceramic method and characterized by single crystal X-ray diffraction: K2SmP2S7 crystallizes in the monoclinic space group C2 (no. 5) with the ...
    • Comparative study of the electrochemical behavior and analytical applications of (bio)sensing platforms ... 
      Primo, E. N.; Gutierrez, F. A.; Luque, G. L.; Dalmasso, P. R.; Gasnier, A.; Jalit, Y.; Moreno, M.; Bracamonte, M. V.; Eguílaz Rubio, M.; Pedano, M. L.; Rodríguez, M. C.; Ferreyra, N. F.; Rubianes, M. D.; Bollo Dragnic, Soledad; Rivas, G. A. (Elsevier, 2013)
      tThis review present a critical comparison of the electrochemical behavior and analytical performance ofglassy carbon electrodes (GCE) modified with carbon nanotubes (CNTs) dispersed in different polymers:polyethylenimine ...
    • A high-performance liquid chromatography method for determination 2-(n-(N,N,N-trimethyl)-n-alkyl)-5-alkylfuryl ... 
      Morales, Javier; Zanocco Loyola, Antonio; Günther Sapunar, Germán; Lemp Miranda, Else (2006)
      A high-performance liquid chromatography (HPLC) method for the determination of 2-(4-(N,N,N-trimethyl)-butyl)-5-dodecylfuryl bromide (DFTA) in dipalmitoylphophatidil-choline (DPPC) liposome solutions has been developed. ...
    • Microsomal oxidative damage promoted by acetaminophen metabolism 
      Letelier Muñoz, María Eugenia; López Valladares, Miguel; Peredo Silva, Liliana; Rojas Sepúlveda, Daniel; Aracena, Paula (PERGAMON-ELSEVIER SCIENCE LTD., 2011-10)
      Adverse reactions of acetaminophen have been associated to oxidative stress, which may be elicited by reactive oxygen species (ROS) and/or production of the metabolite NAPQI. Both phenomena would arise through the activity ...
    • Singlet Oxygen Reactions with Flavonoids. A Theoretical – Experimental Study 
      Morales, Javier; Günther Sapunar, Germán; Zanocco Loyola, Antonio; Lemp Miranda, Else (2007-07)
      Detection of singlet oxygen emission, lmax = 1270 nm, following laser excitation and steady-state methods were employed to measure the total reaction rate constant, kT, and the reactive reaction rate constant, kr, for the ...
    • Solvent effects on reactions of singlet molecular oxygen, O-2((1)triangle(g)), with antimalarial drugs 
      Lemp Miranda, Else; Valencia, Cristina; Zanocco Loyola, Antonio (ELSEVIER SCIENCE SA, 2004-11-01)
      Detection of O2(1 g) emission, λmax = 1270 nm, following laser excitation and steady-state methods were employed to measure total reaction rate constants, kT, for the reaction between singlet oxygen and the antimalarial ...