Now showing items 601-620 of 2558

    • Rojas, Carolina; García, Michelle P.; Polanco, Alan F.; González Osuna, Luis; Sierra Cristancho, Alfredo José; Melgar Rodríguez, Samanta Azucena; Cafferata Chea, Emilio Alfredo; Vernal Astudillo, Rolando Marcelo (Frontiers Media, 2021)
      Periodontitis is an oral inflammatory disease in which the polymicrobial synergy and dysbiosis of the subgingival microbiota trigger a deregulated host immune response, that leads to the breakdown of tooth-supporting ...
    • Hernández Cáceres, María Paz; Muñoz, Leslie; Pradenas, Javiera M.; Pena, Francisco; Lagos, Pablo; Aceiton, Pablo; Owen, Gareth I.; Morselli, Eugenia; Criollo Céspedes, Alfredo Guillermo; Ravasio, Andrea; Bertocchi, Cristina (Frontiers Media, 2021)
      Proper execution of cellular function, maintenance of cellular homeostasis and cell survival depend on functional integration of cellular processes and correct orchestration of cellular responses to stresses. Cancer ...
    • Sansores España, Daniel; Carrillo Ávila, Arelly; Melgar Rodríguez, Samanta Azucena; Díaz Zúñiga, Jaime; Martínez Aguilar, Víctor (Medicina Oral, España, 2021)
      Background: Alzheimer's disease (AD), the main cause of dementia in the adult population, is characterized by a progressive loss of cognitive function. It is considered that neuroinflammation plays a fundamental role in ...
    • Buvinic Radic, Sonja Milena; Balanta Melo, Julián; Kupczik, Kornelius; Vásquez, Walter; Beato Rojas, Carolina Andrea; Toro Ibacache, María Viviana (MDPI, 2021)
      The masticatory system is a complex and highly organized group of structures, including craniofacial bones (maxillae and mandible), muscles, teeth, joints, and neurovascular elements. While the musculoskeletal structures ...
    • Ríos, Javiera; Sequeida, Álvaro; Albornoz, Amelina; Budini, Mauricio Fernando (Frontiers Media SA, 2021)
      Chaperone-mediated autophagy (CMA) represents a specific way of lysosomal protein degradation and contrary to macro and microautophagy is independent of vesicles formation. The role of CMA in different physiopathological ...
    • Bordagaray San Martín, María José; Fernández, Alejandra; Garrido, Mauricio; Astorga, Jéssica; Hoare Teuche, Anilei Paz; Hernández Ríos, Marcela (Frontiers Media, 2021)
      Apical periodontitis is an inflammatory disease of microbial etiology. It has been suggested that endodontic bacterial DNA might translocate to distant organs via blood vessels, but no studies have been conducted. We aimed ...
    • Bachelet Norelli, Vivienne Christine; Navarrete, María S.; Barrera Riquelme, Constanza; Carrasco, Víctor A.; Dallaserra Albertini, Matías; Díaz, Rubén A.; Ibarra, Álvaro A.; Lizana, Francisca J.; Meza Ducaud, Nicolás; Saavedra, Macarena G.; Tapia Davegno, Camila; Vergara, Alonso F.; Villanueva Maffei, Julio Alberto (BMC, 2021)
      Background: The Iberoamerican Cochrane Network is currently developing an extensive project to identify Spanishlanguage journals that publish original clinical research in Spain and Latin America. The project is called ...
    • Xaus Aguayo, Gloria Mercedes; Leighton Ferrer, Catherine Grace; Moncada Cortés, Gustavo (Universidad de Chile, Área Operatoria Dental, 2013)
    • Niklander, Sven; Bordagaray San Martín, María José; Fernández, Alejandra; Hernández Ríos, Emma Marcela (MDPI, 2021)
      Vascular endothelial growth factors (VEGFs) are vital regulators of angiogenesis that are expressed in response to soluble mediators, such as cytokines and growth factors. Their physiologic functions include blood vessel ...
    • Corral Núñez, Camila; Altamirano Gaete, Diego; Maureira Vargas, Miguel; Martin Casielles, Javier; Covarrubias Gallardo, Cristián (MDPI, 2021)
      This study aimed to investigate the cytotoxicity and bioactivity of a novel nanocomposite containing nanoparticles of bioactive glass (nBGs) on human dental pulp stem cells (hDPSCs). nBGs were synthesized by the sol-gel ...
    • Urzúa Orellana, Blanca; Ahumada Ossandón, Richard; Casa Weisser, Daniel; Franco Martínez, María Eugenia; Ortega Pino, Ana (Elsevier, 2021)
      Background/purpose: There are few studies comparing the expression of enamel proteins, such as amelogenin, and cytokeratins in cyst and odontogenic tumors like in ameloblastoma and odontogenic keratocyst, indicating that ...
    • Kramer, Susanne; Fuentes, Ignacia; Yubero, María Joao; Lucky, Anne W.; Palisson, Francis (Mosby-Elsevier, 2020)
    • Kramer, Susanne; Fuentes, Ignacia; Yubero, María Joao; Encina, Carolina; Farfán, José; Araya, Ignacio; Castillo Bennett, Jimena; Fuentes, Constanza; McNab, María Elena; Zillmann, Gisela; Valle, Marcelo; Lucky, Anne W.; Palisson, Francis (Mosby-Elsevier, 2020)
    • Romito, Giuseppe; Feres, Magda; Gamonal Aravena, Jorge; Gómez, Mariel; Carvajal, Paola; Pannuti, Claudio; Duque Duque, Andrés; Romanelli, Hugo; Rosing, Cassiano Kuchenbecker; Aranguiz Freyhofer, Vicente; Cavagni, Juliano; Fischer, Ricardo Guimaraes; Figueiredo, Luciene; Campos de Almeida Carrer, Fernanda; Malheiros, Zilson; Stewart, Bernal; Sanz, Mariano; Ryan, María (Sociedade Brasileira de Pesquisa Odontologica, 2020)
      Periodontal diseases are considered a worldwide public health problem, owing to their high prevalence in developed and developing countries. Periodontitis may lead to tooth loss, which can impact oral health-related quality ...
    • Gamonal Aravena, Jorge; Bravo, Joel; Malheiros, Zilson; Stewart, Bernal; Morales Chvets, Alicia; Cavalla, Franco; Gómez, Mariel (Sociedade Brasileira de Pesquisa Odontologica, 2020)
      A high level of general and oral health are invaluable assets, a factor not always considered a basic human right for their better life quality. The mouth is a critical point of contact with the external environment, which ...
    • Carvajal, Paola; Vernal Astudillo, Rolando; Reinero, Daniela; Malheiros, Zilson; Stewart, Bernal; Pannuti, Claudio Mendes; Romito, Giuseppe Alexandre (Sociedade Brasileira de Pesquisa Odontologica, 2020)
      The epidemiological data on gingivitis and periodontitis in Latin America are scarce, as the majority of the Latin American studies have analyzed probing depth instead of clinical attachment loss. Reported data have shown ...
    • Peña Oyarzún, Daniel; Batista González, Ana; Kretschmar, Catalina; Burgos, Paulina; Lavandero González, Sergio; Morselli, Eugenia; Criollo Céspedes, Alfredo (Elsevier, 2020)
      Polycystin-2 (PC2) is a calcium channel that can be found in the endoplasmic reticulum, the plasmatic membrane, and the primary cilium. The structure of PC2 is characterized by a highly ordered C-terminal tail with an ...
    • Lopes Galante, M.; Lugo, D.; Castro G, Carmen Gloria; Ovalle, M.; Pischel, N.; Giraldes, A.; Carrer, F. (Oxford, 2020)
    • Hoare, Anilei; Wang, Hui; Meethil, Archana; Abusleme Ramos, Loreto; Hong, Bo-Young; Moutsopoulos, Niki M.; Marsh, Philip D.; Hajishengallis, George; Díaz, Patricia I. (Springernature, 2020)
      Recent studies describe in detail the shifts in composition of human-associated polymicrobial communities from health to disease. However, the specific processes that drive the colonization and overgrowth of pathogens ...
    • Rivas, Solange; Silva, Patricio; Reyes Rojas, Montserrat; Sepúlveda, Hugo; Solano, Luis; Acuña, Juan; Guerrero, Marisol; Varas Godoy, Manuel; Quest, Andrew F. G.; Montecino, Martín; Torres Gómez, Vicente (Nature, 2020)
      Tumor hypoxia and the hypoxia inducible factor-1, HIF-1, play critical roles in cancer progression and metastasis. We previously showed that hypoxia activates the endosomal GTPase Rab5, leading to tumor cell migration and ...