Now showing items 181-200 of 2801

    • Quaglio, Deborah; Mangoni, María Luisa; Stefanelli, Roberta; Corradi, Silvia; Casciaro, Bruno; Vergine, Valeria; Lucantoni, Federica; Cavinato, Luca; Cammarone, Silvia; Loffredo, María Rosa; Cappiello, Floriana; Calcaterra, Andrea; Erazo Giuffra, Silvia; Ghirga, Francesca; Mori, Mattia; Imperi, Francesco; Ascenzioni, Fiorentina; Botta, Bruno (American Chemical Society, 2020)
      Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible ...
    • Ramírez Carrasco, Patricia; Paredes Toledo, Javier; Romero Hasler, Patricio; Soto Bustamante, Eduardo; Díaz Calderón, Paulo; Robert Canales, Paz; Giménez, Begoña (MDPI, 2020)
      Beeswax-based organogels were formulated with linseed oil and curcumin according to a statistical design to increase the oxidative stability of spreadable meat products (pate) where these organogels (OGCur) were incorporated ...
    • Segura, Camilo; Vargas Cortés, Víctor; Valenzuela Fernández, Rodrigo; Silva Danna, Caroline; Osorio Román, Igor (American Chemical Society, 2020)
      Because of the growing demand for the use of photovoltaic cells to transform solar energy into electrical energy, radiation concentration systems such as luminescent solar concentrators (LSCs) have gained significant ...
    • Torrado Salmerón, Carlos; Guarnizo Herrero, Víctor; Gallego Arranz, Teresa; Val-Sabugo, Yvonne del; Torrado, Guillermo; Morales Valenzuela, Javier; Torrado Santiago, Santiago (MDPI, 2020)
      Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the ...
    • Castro Álvarez, Alejandro; Gil Sánchez, Yolimar; Llanos, Leonel; Aravena, Daniel (Royal Society of Chemistry, 2020)
      The current figure of merit to evaluate Single Molecule Magnet (SMM) performance is the blocking temperature (T-B). The best SMMs showT(B)values close to liquid nitrogen boiling point (77 K) while their Orbach effective ...
    • De Bonfils, Paul; Verron, Elise; Sandoval Altamirano, Catalina; Jaque Olmedo, Pablo; Moreau, Xavier; Gunther Sapunar, Germán; Nun, Pierrick; Coeffard, Vincent (Amer Chemical, 2020)
      A series of functionalized 6-alkoxy phenalenones was prepared through an unprecedented oxidative dealkylation of readily available phenalene precursors. The starting phenalenes were efficiently synthesized via an aminocatalyzed ...
    • Chávez, Myra; Morales, Rodrigo A.; López Crisosto, Camila; Roa, Juan; Allende Connelly, Miguel; Lavandero González, Sergio (Nature, 2020)
      Autophagy is an evolutionarily conserved process that plays a key role in the maintenance of overall cellular health. While it has been suggested that autophagy may elicit cardioprotective and pro-survival modulating ...
    • Corbalán, Ramón; García, Mauricio; Garrido Olivares, Luis; García Nannig, Lorena; Pérez, Gonzalo; Mellado, Rosemarie; Zalaquett, Ricardo; Chiong, Mario; Quitral, Jorge; Lavandero González, Sergio (Wiley, 2020)
      Background Soluble vascular cell adhesion molecule-1 has been associated with long-term cardiovascular mortality in patients with stable coronary artery disease and to the development of new atrial fibrillation in subjects ...
    • Hernández Cáceres, María Paz; Cereceda, Karina; Hernández, Sergio; Li, Ying; Narro, Carla; Rivera, Patricia; Silva, Patricio; Ávalos, Yenniffer; Jara, Claudia; Burgos, Paulina; Toledo Valenzuela, Lilian; Lagos, Pablo; Cifuentes Araneda, Flavia; Pérez Leighton, Claudio; Bertocchi, Cristina; Clegg, Deborah J.; Criollo Céspedes, Alfredo; Tapia Rojas, Cheril; Burgos, Patricia V.; Morselli, Eugenia (Taylor & Francis, 2020)
      High-fat diet (HFD)-induced obesity is associated with increased cancer risk. Long-term feeding with HFD increases the concentration of the saturated fatty acid palmitic acid (PA) in the hypothalamus. We previously showed ...
    • Pinto, Mauricio; Córdova Delgado, Miguel; Martínez Retamal, Ignacio; Muñoz Medel, Matías; Bravo, M. Loreto; Duran, Doris; Toledo Villanueva, Francisco Javier; Sánchez, César; Acevedo, Francisco; Mondaca, Sebastián; Koch, Erica; Ibáñez, Carolina; Galindo, Héctor; Madrid, Jorge; Nervi, Bruno; Peña, José; Torres, Javiera; Owen, Gareth I.; Corvalán, Alejandro H.; Armisén, Ricardo; Garrido, Marcelo (MDPI, 2020)
      Gastric cancer (GC) is a complex and heterogeneous disease. In recent decades, The Cancer Genome Atlas (TCGA) and the Asian Cancer Research Group (ACRG) defined GC molecular subtypes. Unfortunately, these systems require ...
    • Santibáñez, Luis; Escalona, Néstor; Torres, Julia; Kremer, Carlos; Cancino, Patricio; Spodine Spiridonova, Evgenia (MDPI, 2020)
      The aerobic oxidation of cyclohexene was done using the heterometallic metal organic frameworks (MOFs) {[La2Cu3(mu-H2O)(ODA)(6)(H2O)(3)].3H(2)O}(n)(LaCuODA)) (1) and {[La2Co3(ODA)(6)(H2O)(6)].12H(2)O}(n)(LaCoODA) (2) as ...
    • Rodríguez Lavado, Julio; Lorente Sánchez, Alejandro; Flores, Eric; Ochoa, Andrés; Godoy, Fernando; Jaque Olmedo, Pablo; Saitz Barria, Claudio (Royal Society of Chemistry, 2020)
      This article reports the synthesis and characterisation of two lower rim calix[4]arene derivatives with thiourea as spacer and pyrene or methylene-pyrene as fluorophore. Both derivatives exhibit a fluorimetric response ...
    • Díaz, C.; Valenzuela, M. L.; Cifuentes Vaca, O.; Segovia, M. (Springer, 2020)
      A mixture of a nanostructured Rh/RhO(2)phase was easily obtained by thermally treating the macromolecular Chitosan center dot(RhCl3)(x)precursor, while the Rh/Rh(2)O(3)phase was obtained by pyrolyzing PSP-4-PVP center ...
    • Díaz Dinamarca, Diego A.; Hernández, Carlos; Escobar, Daniel F.; Soto, Daniel A.; Muñoz, Guillermo A.; Badilla, Jesús F.; Manzo, Ricardo A.; Carrión, Flavio; Kalergis, Alexis M.; (MDPI, 2020)
      Group BStreptococcus(GBS) is the primary etiological agent of sepsis and meningitis in newborns and is associated with premature birth and stillbirth. The development of a licensed vaccine is one of the pending challenges ...
    • Lapierre Acevedo, Lisette; Cornejo Kelly, Javiera; Zavala, Sebastián; Galarce Gálvez, Nicolás Elías; Sánchez García, Fernando; Benavides Vicencio, María Belén; Guzmán Muñoz, Miguel; Sáenz Iturriaga, Leonardo (MDPI, 2020)
      Salmonella Infantis is a zoonotic pathogen that causes gastroenteritis in humans and animals, with poultry being its main reservoir. In Chile, there are no data to characterize S. Infantis strains in poultry production. ...
    • Gallardo Garrido, C.; Cho, Y.; Cortés Ríos, J.; Vásquez Velásquez, David; Pessoa Mahana, C. David; Araya Maturana, R.; Pessoa Mahana, Hernán; Faúndez, M. (Elsevier, 2020)
      Nitrofurans (5-nitro-2-hydrazonylfuran as pharmacophore) are a group of widely used antimicrobial drugs but also associated to a variety of side effects. The molecular mechanisms that underlie the cytotoxic effects of ...
    • Riquelme, Natalia; Robert Canales, Paz; Troncoso, Elizabeth; Arancibia, Carla (Royal Society of Chemistry, 2020)
      Hydrocolloids are used as stabilizing agents in order to enhance the physical stability of emulsions during their storage. However, they can also play an important role in nutrient release and bioavailability. In this ...
    • Muñoz, Daniel; Rivera Meza, Mario; Flores Bastías, Osvaldo; Quintanilla González, María Elena; Karahanian, Eduardo (Socidrogalcohol. Sociedad Científica Española de Estudio sobre el Alcohol, el Alcoholismo y las otras Toxocomanías, 2020)
      Tras consumir etanol, el disulfiram incrementa los niveles de acetaldehído en sangre y genera una reacción aversiva que desalienta el consumo de alcohol. Dados los importantes efectos secundarios del disulfiram, es ...
    • Robinson Duggon, José; Pizarro, Nancy; Gunther Sapunar, Germán; Zúñiga Núñez, Daniel; Edwards, Ana María; Greer, Alexander; Fuentealba, Denis (Wiley, 2020)
      Toluidine blue O (TBO) is a water-soluble photosensitizer that has been used in photodynamic antimicrobial and anticancer treatments, but suffers from limited solubility in hydrophobic media. In an effort to incrementally ...
    • Puente Díaz, Luis; Vega Gálvez, Antonio; Fuentes, Ivette; Stucken, Karina; Rodríguez, Ángela; Pastén, Alexis (Springer, 2020)
      Physalis peruvianaL. fruits are rich in bioactive compounds with health benefits. Processing of physalis into pulp with further dehydration has been proposed as a method to increase shelf life and preserve bioactive ...