Now showing items 1701-1720 of 11560

    • Contreras Muñoz, Héctor; López Moncada, Fernanda; Castellón Vera, Enrique (Spandidos, 2020)
      Prostate cancer (PCa) is the leading cause of male cancer-associated mortality worldwide. Mortality is associated with metastasis and hormone resistance. Cellular, genetic and molecular mechanisms underlying metastatic ...
    • Rivas, José; Díaz, Nicolás; Silva, Ian; Morales, Dana; Lavanderos, Boris; Álvarez, Alhejandra; Saldías Maulén, María Paz; Pulgar Pulgar, Eduardo; Cruz Núñez, Pablo; Maureira, Diego; Flores Utreras, Guillermo; Colombo Flores, Alicia; Blanco, Constanza; Contreras Muñoz, Héctor; Jaña, Fabián; Gallegos Méndez, Iván; Concha Nordemann, Miguel; Vergara Jaque, Ariela; Poblete, Horacio; González, Wendy; Varela Lekanda, Diego; Trimmer, James; Cáceres Lluch, Mónica Andrea; Cerda Arancibia, Óscar (Wiley, 2020)
      Transient receptor potential melastatin 4 (TRPM4) is a Ca2+-activated nonselective cationic channel that regulates cell migration and contractility. Increased TRPM4 expression has been related to pathologies, in which ...
    • Calderón Garcidueñas, Lilian; Herrera Soto, Andrea; Jury, Nur; Maher, Bárbara; González Maciel, Angélica; Reynoso Robles, Rafael; Ruiz Rudolph, Pablo; van Zundert, Brigitte; Varela Nallar, Lorena (Elsevier, 2020)
      Exposure to air pollutants is associated with an increased risk of developing Alzheimer's disease (AD). AD pathological hallmarks and cognitive deficits are documented in children and young adults in polluted cities (e.g. ...
    • Verdugo Salgado, Ricardo; Di Genova, Alex; Herrera Cisterna, Luisa; Moraga Vergara, Mauricio; Acuña Patzke, Mónica; Berríos del Solar, María Soledad; Llop Romero, Elena; Valenzuela, Carlos Y.; Bustamante Calderón, María Leonor; Digman, Dayhana; Symon Maturana, Adriana; Asenjo, Soledad; López Contreras, Pamela; Blanco, Alejandro E.; Suazo Sanhueza, José; Barozet, Emmanuelle; Caba, Fresia; Villalón Calderón, Marcelo; Alvarado Orellana, Sergio; Cáceres Lillo, Dante; Salgado, Katherine; Portales, Pilar; Moreno Estrada, Andrés; Gignoux, Christopher; Sandoval, Karla; Bustamante, Carlos; Eng, Celeste; Huntsman, Scott; Burchard, Esteban; Loira, Nicolás; Maass Sepúlveda, Alejandro; Cifuentes Ovalle, Lucía (Sociedad de Biología de Chile, 2020)
      Background Current South American populations trace their origins mainly to three continental ancestries, i.e. European, Amerindian and African. Individual variation in relative proportions of each of these ancestries may ...
    • Zafereo, Mark; McIver, Bryan; Vargas Salas, Sergio; Domínguez, Jose; Steward, David L.; Holsinger, F. Christopher; Kandil, Emad; Williams, Michelle; Loyola, Soledad; Solar, Antonieta; Roa, Juan; Leon, Augusto; Droppelman, Nicolas; Lobos, Maite; Arias, Tatiana; Kong, Christina S.; Busaidy, Naifa; Grubbs, Elizabeth G.; Graham, Paul; Stewart, John; Tang, Alice; Wang, Jiang; Orloff, Lisa; Henriquez, Marcela; Lagos, Marcela; Osorio, Miren; Schachter, Dina; Franco, Carmen; Medina, Francisco; Wohllk Gonzalez, Nelson; Diaz, Rene; Veliz Lopez, Jesus; Horvath, Eleonora; Tala, Hernan; Pineda Bravo, Pedro; Arroyo Albala, Patricia; Vásquez, Felix; Traipe, Eufrosina; Marin, Luis; Miranda, Giovanna; Bruce, Elsa; Bracamonte, Milagros; Mena, Natalia; Gonzalez, Hernan E. (Mary Ann Liebert, 2020)
      Background: Although most thyroid nodules with indeterminate cytology are benign, in most of the world, surgery remains as the most frequent diagnostic approach. We have previously reported a 10-gene thyroid genetic ...
    • Babazade, Rovnat; Lin, Yu-li; Hidalgo Valles, Guillermo; Capogna, Giorgio; Micaglio, Massimo; Vadhera, Rakesh B.; Gebhard, Ralf E. (Elsevier, 2020)
    • Roco, Ángela; Nieto, Elena; Suárez, Marcelo; Rojo, Mario; Bertoglia, María Paz; Verón, Gabriel; Tamayo, Francisca; Arredondo, Annabella; Cruz, Daniela; Muñoz, Jessica; Bravo, Gabriela; Salas, Patricio; Mejías, Fanny; Godoy, Gerald; Véliz, Paulo; Quiñones Sepúlveda, Luis (Frontiers Media, 2020)
      Background Vitamin K antagonists (VKA) are used as prophylaxis for thromboembolic events in patients with cardiovascular diseases. The most common VKA are warfarin and acenocoumarol. These drugs have a narrow therapeutic ...
    • Morgado Carrasco, D.; Vargas Mora, Pablo; Fustà-Novell, X. (Wiley, 2020)
    • Morgado Carrasco, Daniel; Vargas Mora, Pablo (SAGE, 2020)
    • Farfán, Nancy; Orellana Serradell, Octavio; Herrera, Daniela; Chrzanowsky, Dominique; Cubillos, Paulina; Marín, Gabriel; García de Herreros, Antonio; Castellón Vera, Enrique; Contreras Muñóz, Héctor (Spandidos Publications, 2020)
      Zinc finger protein SNAI1 (SNAIL) and zinc finger protein SNAI2 (SLUG) transcription factors promote epithelial-mesenchymal transition, a process through which epithelial cells acquire a mesenchymal phenotype, increasing ...
    • Reyes, Humberto B. (Sociedad Médica de Santiago, 2020)
      This paper summarizes the main features of review articles in medical topics. Articles can be classified as narrative reviews, systematic reviews or meta-analysis. Narrative reviews are appropriate to update etiology, ...
    • Lardone, María Cecilia; Busch, Alexander; Santos, José; Miranda, Patricio; Eyheramendy, Susana; Pereira Scalabrino, Ana; Juul, Anders; Almstrup, Kristian; Mericq, Verónica (Endocrine Society, 2020)
      Context: Voice break, as a landmark of advanced male puberty in genome-wide association studies (GWAS), has revealed that pubertal timing is a highly polygenic trait. Although voice break is easily recorded in large cohorts, ...
    • Soto Covasich, J.; Reyes Farías, Marjorie; Torres, R. F.; Vásquez, Karla; Duarte Silva, Lissette; Quezada, J.; Jiménez Patiño, Paula; Pino, M. T.; García Nannig, Lorena; Mercado, L.; García Díaz, Diego (Elsevier, 2020)
      The establishment of a chronic inflammatory state in the adipose tissue contributes to obesity-associated insulin resistance. Hence, disrupting the inflammatory response elicited by obesity remains a relevant target to ...
    • Osorio, H.; Toro, J.; Schorwer, K.; Riveros, A.; Cárdenas Valenzuela, Julio (Sociedad Chilena de Anatomía, 2020)
      Reviewing a century of history, the development of anatomical activities in the city of Concepcion, in the south of Chile, did not occur without difficulties. The present work gathered the historical background related ...
    • García, Coralith; Ochoa, Teresa; Neyra, Edgar; Bustamante, Beatriz; Ponce Olmos, Carolina; Calderón, Enrique J.; Vargas Munita, Sergio (AEM Asociación Española de Micología, 2020)
      Background: Pneumocystis jirovecii primary infection occurs asymptomatically before 6 months of age, suggesting that the infection is acquired very early in life. Furthermore, Pneumocystis pneumonia has been described in ...
    • Oyarzún, Andrés; Barrientos Mendoza, Cristián; Barahona Vásquez, Maximiliano; Martínez Herold, Álvaro; Soto Arellano, Verónica; Courtin, Carolina; Cruz Montecinos, Carlos (Wiley, 2020)
      Introduction Total knee arthroplasty (TKA) can improve knee function in the general population, but challenges arise for TKA use in haemophilic patients (HPs). Aim This study aimed to evaluate the midterm clinical ...
    • González Martínez, Sebastián; Beauthier, Jean-Pol (Elsevier, 2020)
      The duration of a victim's incapacity for work is a factor in sentencing for violent crimes in countries that are heirs to eighteen-century European penal codes. In this article, we consider pitfalls of this criterion. A ...
    • Olivera, Ignacio; Grau, Carlos; Dibarboure, Hugo; Torres Torretti, Juan Pablo; Mieres, Gustavo; Lazarov, Luis; Álvarez, Fabián; López Yescas, Juan Guillermo (BMC, 2020)
      Background: The phased withdrawal of oral polio vaccine (OPV) and the introduction of inactivated poliovirus vaccine (IPV) is central to the polio ‘end-game’ strategy. Methods: We analyzed the cost implications in Chile ...
    • Chen, Xiaoying; Wang, Xia; Delcourt, Candice; Li, Jingwei; Arima, Hisatomi; Hackett, Maree L.; Robinson, L.; Lavados, Pablo M.; Lindley, Richard I.; Chalmers, John; Anderson, Craig S. (Lippincott Williams & Wilkins, 2020)
      Background and Purpose-Patient-centered outcomes are important. We aimed to determine predictors of health-related quality of life (HRQoL) and develop utility-weighted modified Rankin Scale (mRS) scores in thrombolyzed ...