Now showing items 761-780 of 11560

    • Bernal Ramírez, Judith; Díaz Vesga, Magda; Talamilla, Matías; Méndez, Andrea; Quiroga, Clara; Garza Cervantes, Javier; Lázaro-Alfaro, Anay; Jerjes Sánchez, Carlos; Henríquez Luna, Hilda del Carmen; García Rivas, Gerardo; Pedrozo Cibils, Zully Rocio Evangelina (2021)
      The right and left ventricles have traditionally been studied as individual entities. Furthermore, modifications found in diseased left ventricles are assumed to influence on right ventricle alterations, but the connection ...
    • Aguilera, Bernardo; Pérez Gómez, Javiera; DeGrazia, David (BMC, 2021)
      Background: The use of great apes (GA) in invasive biomedical research is one of the most debated topics in animal ethics. GA are, thus far, the only animal group that has frequently been banned from invasive research; ...
    • Cruz Montecinos, Carlos Vicente; Cerda Villablanca, Mauricio; Becerra Poblete, Pablo Andrés; Tapia Malebrán, Claudio Yerko; Núñez Cortés, Rodrigo Ignacio; Latorre García, Rodrigo; Freitas, Sandro; Cuesta Vargas, Antonio (BMC, 2021)
      Background The relevance of local twitch response (LTR) during dry needling technique (DNT) is controversial, and it is questioned whether LTR is necessary for successful outcomes. Furthermore, because the LTR during the ...
    • Halabi, Diego; Richter, Hans G.; Méndez, Natalia; Kahne, Thilo; Spichiger, Carlos; Salazar, Esteban; Torres, Fabiola; Vergara, Karina; Serón Ferre, María Josefa; Torres Farfán, Claudia (Frontiers Media, 2021)
      Compelling evidence in rats support the idea that gestational chronodisruption induces major changes in maternal circadian rhythms and fetal development and that these changes impact adult life at many physiological levels. ...
    • Pérez Domínguez, Francisco Javier; Carrillo Beltrán, Diego Antonio; Blanco Santana, Rancés; Muñoz, Juan P.; León Cruz, Grettell; Corvalán, Alejandro H.; Urzúa Tobar, Ulises de la Cruz; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Pirin is a protein which is detected at low levels in normal tissues. However, it is detected at high levels in multiple cancers, particularly in melanomas, cervical cancer or squamous cell lung carcinomas. ...
    • Troncoso Magñin, Mayarling Francisca; Pavez Giani, Mario Gustavo; Wilson Rodríguez, Carlos Antonio; Lagos Cerón, Daniel Alejandro; Durán Gárate, Javier Andre; Ramos, Sebastián; Barrientos Briones, Genaro Christian; Silva, Patricio; Llanos Vidal, Paola Andrea; Basualto Alarcón, Carla Edith; Westenbrink, B. Daan; Lavandero González, Sergio Alejandro; Estrada Hormazábal, Manuel Iván (BMC, 2021)
      Background Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that ...
    • Bravo, Verónica; Katz Zondek, Assaf; Porte, Lorena; Weitzel, Thomas; Varela, Carmen; González Escalona, Narjol; BlondelI, Carlos J. (Public Library Science, 2021)
      Campylobacter jejuni and Campylobacter coli are the leading cause of human gastroenteritis in the industrialized world and an emerging threat in developing countries. The incidence of campylobacteriosis in South America ...
    • Guzmán Palma, Pablo; Contreras, Esteban G.; Mora, Natalia; Smith, Macarena; González Ramírez, M. Constanza; Campusano, Jorge M.; Sierralta Jara, Jimena Alejandra; Hassan, Bassem A.; Oliva, Carlos (Frontiers Media, 2021)
      Neurogenesis is achieved through a sequence of steps that include specification and differentiation of progenitors into mature neurons. Frequently, precursors migrate to distinct positions before terminal differentiation. ...
    • Kehdy, Fernanda S. G.; Pita Oliveira, Murilo; Scudeler, Mariana M.; Torres Loureiro, Sabrina; Zolini, Camila; Moreira, Rennan; Michelin, Lucas A.; Alvim, Isabela; Silva Carvalho, Carolina; Furlan, Vinicius C.; Aquino, María M.; Santolalla, Meddly L.; Borda, Víctor; Soares Souza, Giordano B.; Jaramillo Valverde, Luis; Vásquez Domínguez, Andrés; Sánchez Neira, César; Aguiar, Renato S.; Verdugo Salgado, Ricardo Alejandro; Connor, Timothy D. O.; Guio, Heinner; Tarazona Santos, Eduardo; Leal, Thiago P.; Rodrigues Soares, Fernanda (Soc Brasil Genética, 2021)
      For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there is a convincing evidence of association in Asians with influenza-induced SARS for TMPRSS2-rs2070788, tag-SNP of the eQTL rs383510. This case illustrates the ...
    • González, Andrea; Valero Breton, Mayalen; Huerta Salgado, Camila Francisca; Achiardi, Oscar; Simon, Felipe; Cabello Verrugio, Claudio Alejandro (Pagepress, 2021)
      Sarcopenia is a highly prevalent complication of non-alcoholic fatty liver disease (NAFLD). We aimed to conduct a systematic review and meta-analyses to elucidate the exercise training (ET)'s efficacy on NAFLD adult patients' ...
    • Palacios Rodríguez, Helmer Emilio; Hiroe, Nao; Guzmán Rodríguez, Mónica Andrea; Caicedo, Yaset; Saldarriaga, Luis; Ordoñez, Carlos A.; Funabiki, Tomohiro (Corporación Editora Medica Valle, Colombia, 2021)
      Trauma damage control seeks to limit life-threatening bleeding. Sequential diagnostic and therapeutic approaches are the current standard. Hybrid Room have reduced hemostasis time by integrating different specialties and ...
    • Thomson, P.; Núñez Figueroa, Paulina Javiera; Quera Pino, Rodrigo Enrique; Bay, C. (Elsevier, 2021)
      The intestinal microbiota is made up of billions of microorganisms that coexist in an organised ecosystem, where strict and facultative anaerobic bacteria predominate. The alteration or imbalance of these microorganisms, ...
    • Stahl, Bernd Carsten; Akintoye, Simisola; Bitsch, Lise; Bringedal, Berit; Eke, Damian; Farisco, Michele; Grasenick, Karin; Guerrero Antequera, Manuel Eduardo; Knight, William; Leach, Tonii; Nyholm, Sven; Ogoh, George; Rosemann, Achim; Salles, Arleen; Trattnig, Julia; Ulnicane, Inga (Routledge Journals, Taylor & Francis, 2021)
      Drawing on more than eight years working to implement Responsible Research and Innovation (RRI) in the Human Brain Project, a large EU-funded research project that brings together neuroscience, computing, social sciences, ...
    • Zarate, Ana María; Espinosa Bustos, Christian; Guerrero, Simón; Fierro, Angélica; Oyarzún Ampuero, Felipe; Geoffery Quest, Andrew; Di Marcotullio, Lucía; Loricchio, Elena; Caimano, Miriam; Calcaterra, Andrea; González Quiroz, Matías; Aguirre, Adam; Meléndez, Jaime; Salas, Cristian O. (MDPI, 2021)
      The Smoothened (SMO) receptor is the most druggable target in the Hedgehog (HH) pathway for anticancer compounds. However, SMO antagonists such as vismodegib rapidly develop drug resistance. In this study, new SMO antagonists ...
    • García Concha, Paula Andrea; Fredes, Carolina; Cea, Inés; Lozano Sánchez, Jesús; Leyva Jiménez, Francisco Javier; Robert, Paz; Vergara, Cristina; Jiménez Patiño, Paula Andrea (MDPI, 2021)
      Pressurized liquid extraction (PLE) is a clean and environmentally friendly alternative for the recovery of bioactive compounds from fruit by-products. Herein we focused on PLE for the extraction of bioactive compounds ...
    • HilzingerI, Rebecca; Duarte, Javiera; Hench, Bárbara; Hunger, Christina; Schweitzer, Jochen; Krause, Mariane; Fischersworring, Martina María (Public Library Science, 2021)
      There is evidence that systemic therapy is effective, but there is little evidence about meaningful moments in systemic therapy in general, and none at all in systemic therapy for social anxiety disorders. Meaningful moments ...
    • Blanco, Rances; Carrillo Beltrán, Diego Antonio; Muñoz, Juan P.; Corvalán, Alejandro H.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Breast cancer (BC) is the most frequent tumor in women worldwide. A minority of BC patients have a family history of the disease, suggesting the importance of environmental and lifestyle factors. Human ...
    • Sánchez Ramírez, Diana C.; Normand, Kaylene; Yang, Zhaoyun; Torres Castro, Rodrigo Hernan; Torres Castro, Rodrigo Hernán (MDPI, 2021)
      Background: The long-term impact of COVID-19 is still unknown. This study aimed to explore post COVID-19 effects on patients chest computed tomography (CT), lung function, respiratory symptoms, fatigue, functional capacity, ...
    • Rozas Rojas, Pablo Sebastián; Pinto, Cristina; Martínez Traub, Francisca José; Díaz Hinojosa, Rodrigo Ignacio; Pérez, Viviana; Becerra, Daniela; Ojeda, Patricia; Ojeda, Jorge; Wright, Madison T.; Mella, Jéssica; Plate, Lars; Henríquez, Juan Pablo; Hetz Flores, Claudio Andrés; Bilches Medinas, Danilo (BMC, 2021)
      Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice ...
    • Jorquera, Gonzalo; Russell, Javier; Monsalves Álvarez, Matías; Cruz, Gonzalo; Valladares-Ide, Denisse; Basualto Alarcón, Carla Edith; Barrientos, Genaro; Estrada, Manuel; Llanos, Paola (MDPI, 2021)
      Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding oligomerization domain-like receptor family (NOD-like) pyrin ...