Rapidly progressive kidney failure associated with neutrophil anticytoplasmic autoantibodies. Anatomo-clinical case Insuficiencia renal rápidamente progresiva asociada a anticuerpos anticitoplasmáticos de neutrófilos. Caso anátomo clínico.
Author
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Wainstein,
Author
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Puelma,
Author
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Carrasco,
Author
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Guzmán Guzmán, Iris P
Admission date
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2019-01-29T14:53:02Z
Available date
dc.date.available
2019-01-29T14:53:02Z
Publication date
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1993
Cita de ítem
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Revista medica de Chile, Volumen 121, Issue 11, 2018, Pages 1295-1299
Identifier
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00349887
Identifier
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https://repositorio.uchile.cl/handle/2250/161173
Abstract
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We report a 63 year old woman with a rapidly progressive renal failure and fever of unknown origin. Laboratory tests showed anemia, increased ESR and a urine analysis compatible with a glomerular disease. Antineutrophil cytoplasmic autoantibodies were positive with a perinuclear pattern. Kidney biopsy showed an autoimmune crescenteric glomerulonephritis. The patient had a bad evolution, dying after a massive hemoptysis. The necropsy showed a disseminated arteritis without compromise of bronchial vessels. The oligosymptomatic presentation of this patient, bearing in mind the anatomo-pathological findings, is noteworthy and emphasizes the usefulness of serological markers as antineutrophil cytoplasmic autoantibodies in the differential diagnosis.
Rapidly progressive kidney failure associated with neutrophil anticytoplasmic autoantibodies. Anatomo-clinical case Insuficiencia renal rápidamente progresiva asociada a anticuerpos anticitoplasmáticos de neutrófilos. Caso anátomo clínico.