Interstitial lung disease and microscopic polyangiitis in chilean patients
Author
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Wurmann Kiblisky, Pamela
Author
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Sabugo Siraqyan, María Francisca
Author
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Elgueta, Fabián
Author
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Mac-Namara, Macarena
Author
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Vergara González, Karen
Author
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Vargas, Daniela
Author
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Molina Cousiño, María Luisa
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Díaz Patino, Juan Carlos
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Gatica Rossi, Héctor
Author
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Goecke Sariego, Irmgadt
Admission date
dc.date.accessioned
2020-04-21T02:09:16Z
Available date
dc.date.available
2020-04-21T02:09:16Z
Publication date
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2020
Cita de ítem
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Sarcoidosis Vasculitis and Diffuse Lung Diseases 2020; 37 (1); 37-42
es_ES
Identifier
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10.36141/svdld.v37i1.7980
Identifier
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https://repositorio.uchile.cl/handle/2250/173963
Abstract
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Objective: To describe the clinical and serological patients characteristics with Microscopic Polyangiitis (MPA) and Interstitial lung disease (ILD). Methods: Of all the patients with AAV diagnosed between 2007-2017 at the Hospital Clinico Universidad de Chile, those with MPA and ILD were selected and studied retrospectively. Results: All patients were Hispanic; median age at diagnosis 65 years (32-84). 59% were female. All were positive for p-ANCA, 16 patients for MPO. Most common manifestations were constitutional symptoms, weight loss and fever. CT-Scans patterns were Usual Interstitial Pneumonia (UIP) in 10 patients, Nonspecific Interstitial Pneumonia (NSIP) in 6 and fibrosis not UIP or NSIP pattern in 1. In 6 cases, ILD was diagnosed 0.5-14 years before MPA and concomitantly in 11. Conclusions: Although infrequent, Microscopic Polyangiitis should be suspected in patients with ILD particularly if extra-pulmonary manifestations that rise the possibility of a systemic illness are present, regardless of the time elapsed between the latter and the diagnosis of this type of lung involvement.