Now showing items 1-11 of 11

    • A comparison of Respiratory Disturbance Variable (RDV),conventional breathing disturbance indexes and oximetry-based metrics 

      Bassi Acuña, Alejandro; Díaz Elizondo, Jessica; Arancibia Henríquez, José Miguel; Ocampo Garcés, Adrián; Vivaldi Véjar, Ennio (Wiley Blackwell, 2016)
    • Autofagia del cardiomiocito: ¿Un nuevo mecanismo de adaptación al estrés o de muerte celular? 

      Aránguiz Urroz, Pablo Daniel; Contreras Ferrat, Ariel Eduardo; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo Hernán; Marambio Morales, Paola Angélica; Toro, Bárbara; Sanhueza Muñoz, Carlos Joaquín; Pennanen Saavedra, Christian; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Chiong Lay, Mario; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      Históricamente, la apoptosis y la necrosis han sido consideradas como las dos formas fundamentales de muerte celular. Sin embargo, evidencias recientes sugieren que la muerte celular programada no está confinada sólo a ...
    • Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death 

      Parra, Valentina; Moraga, Francisco; Kuzmicic, Jovan; López Crisosto, Camila; Troncoso, Rodrigo; Torrealba, Natalia; Criollo Céspedes, Alfredo; Díaz Elizondo, Jessica; Rothermel, Beverly A.; Quest, Andrew F. G.; Lavandero González, Sergio (Elsevier, 2013)
      Ceramides are important intermediates in the biosynthesis and degradation of sphingolipids that regulatenumerous cellular processes, including cell cycle progression, cell growth, differentiation and death. In ...
    • Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells 

      Villena, Joan; Henríquez Luna, Mauricio; Torres Gómez, Vicente; Moraga, Francisco; Díaz Elizondo, Jessica; Arredondo, Cristian; Chiong Lay, Mario; Olea Azar, Claudio; Stutzin Schottlander, Andrés; Lavandero González, Sergio; Quest, Andrew F. G. (ELSEVIER SCIENCE INC, 2008-03-15)
      In lymphocytes, Fas activation leads to both apoptosis and necrosis, whereby the latter form of cell death is linked to delayed production of endogenous ceramide and is mimicked by exogenous administration of long- and ...
    • Especies reactivas de oxígeno en la regulación de volumen y muerte del cardiomiocito activada por estrés hiposmótico 

      Díaz Elizondo, Jessica (Universidad de Chile, 2005)
      Las enfermedades cardiovasculares isquémicas son una de las principales causas de muerte en Chile. En estas patologías, los cardiomiocitos están expuestos a privación de nutrientes, hipoxia y estrés osmótico. Nuestro ...
    • Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes 

      Marambio, Paola; Toro, Barbra; Sanhueza, Carlos; Troncoso, Rodrigo; Parra, Valentina; Verdejo, Hugo; García Nannig, Lorena; Quiroga, Clara; Munafo, Daniela; Díaz Elizondo, Jessica; Bravo Sagua, Roberto; González Burgos, María Julieta; Díaz Araya, Guillermo; Pedrozo Cibils, Zully; Chiong Lay, Mario; Co (2010)
      Aggresomes are dynamic structures formed when the ubiquitin-proteasome system is overwhelmed with aggregation-prone proteins. In this process, small protein aggregates are actively transported towards the microtubule-organizing ...
    • IGF-1: Un factor de crecimiento con acciones cardiovasculares pleiotrópicas. 

      Contreras Ferrat, Ariel Eduardo; Aránguiz Urroz, Pablo Daniel; Díaz Elizondo, Jessica; Chiong Lay, Mario; Muñoz, Juan Pablo; Parra Ortíz, María Valentina; Ibarra, Cristián; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo; Eisner, Verónica; Salas, Daniela; Rodríguez Villarroel, Andrea Elizabeth; Carrasco Alarcón, Loreto del Pilar; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      El factor de crecimiento análogo a insulina tipo 1 (IGF-1) es un péptido relacionado estructural y funcionalmente con insulina que posee efectos mitogénicos y citoprotectores. Sus efectos biológicos dependen de la activación ...
    • Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide 

      Muñoz, Juan Pablo; Chiong Lay, Mario; García Nannig, Lorena; Troncoso Cotal, Rodrigo Andrés; Toro, Barbra; Pedrozo Cibils, Zully; Díaz Elizondo, Jessica; Salas, Daniela; Parra Ortíz, María Valentina; Núñez González, Marco; Hidalgo Tapia, María Cecilia; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2010-02-15)
      We investigate here the role of reactive oxygen species and nitric oxide in iron-induced cardiomyocyte hypertrophy or cell death Cultured rat cardiomyocytes incubated with 20 mu M iron (added as FeCl3-Na nitrilotriacetate, ...
    • Reactive oxygen species inhibit hyposmotic stress-dependent volume regulation in cultured rat cardiomyocytes 

      Díaz Elizondo, Jessica; Chiong Lay, Mario; Rojas Rivera, Diego; Olea Azar, Claudio; Kwon, H. Moo; Lavandero González, Sergio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-12-01)
      Cells have developed compensatory mechanisms to restore cell volume, and the ability to resist osmotic swelling or shrinkage parallels their resistance to necrosis or apoptosis. There are several mechanisms by which cells ...
    • Regulation of Cardiac Autophagy by Insulin-like Growth Factor 1 

      Troncoso, Rodrigo; Díaz Elizondo, Jessica; Espinoza, Sandra P.; Navarro Márquez, Mario F.; Oyarzún, Alejandra P.; Riquelme, Jaime A.; García Carvajal, Ivonne; Díaz Araya, Guillermo; García Nannig, Lorena; Hill, Joseph A.; Lavandero González, Sergio (2013-07)
      Insulin-like growth factor-1 (IGF-1) signaling is a key pathway in the control of cell growth and survival. Three critical nodes in the IGF-1 signaling pathway have been described in cardiomyocytes: protein kinase ...
    • Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species 

      Rojas Rivera, Andrés; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Salas, Daniela; Contreras Ferrat, Ariel Eduardo; Toro, Barbra; Chiong Lay, Mario; Olea Azar, Claudio; Lavandero González, Sergio (ELSEVIER SCIENCE BV, 2009-11-03)
      We investigated the role of Ca2+ in generating reactive oxygen species (ROS) induced by hyposmotic stress (Hypo) and its relationship to regulatory volume decrease (RVD) in cardiomyocytes. Hypo-induced increases in cytoplasmic ...