Browsing by Author "0c25371b-0fff-4ba6-ba53-8894da6256bf"

Now showing items 1-3 of 3

    • Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1 alpha S-Nitrosylation and Transcriptional ... 
      Sanhueza, Carlos; Castillo Bennett, Jimena; Valenzuela Valderrama, Manuel; Contreras, Pamela; Lobos González, Lorena; Campos, América; Wehinger, Sergio; Lladser, Álvaro; Kiessling, Rolf; Leyton Campos, Lisette; Quest, Andrew F. G. (MDPI, 2020)
      Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently hypoxic and the ...
    • Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma ... 
      Ortiz, Rina; Díaz Jara, Jorge; Díaz, Natalia; Lobos González, Lorena; Cárdenas, Areli; Contreras, Pamela; Díaz, María Inés; Otte, Ellen; Cooper- White, Justin; Torres Gómez, Vicente; Leyton Campos, Lisette; Quest, Andrew F. G. (Impact Journals LLC, 2016)
      Caveolin-1 (CAV1) is a scaffolding protein that plays a dual role in cancer. In advanced stages of this disease, CAV1 expression in tumor cells is associated with enhanced metastatic potential, while, at earlier stages, ...
    • The non-receptor tyrosine phosphatase type 14 blocks caveolin-1- enhanced cancer cell metastasis 
      Díaz Valdivia, Natalia; Díaz, Jorge; Contreras, Pamela; Campos, América; Rojas Celis, Victoria; Burgos Ravanal, Renato; Lobos González, Lorena; Torres Gómez, Vicente; Pérez, Viviana I.; Frei, Balz; Leyton Campos, Lisette; Quest, Andrew F. G. (Nature, 2020)
      Caveolin-1 (CAV1) enhanced migration, invasion, and metastasis of cancer cells is inhibited by co-expression of the glycoprotein E-cadherin. Although the two proteins form a multiprotein complex that includes beta-catenin, ...