Browsing by Author "0cf72d9e-5982-4f98-93e0-cf319cc36feb"

Now showing items 1-7 of 7

    • MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjögren's syndrome 
      Sung, H. H.; Castro, I.; González, S.; Aguilera, S.; Smorodinsky, N. I.; Quest, Andrew F. G.; Bahamondes, V.; Alliende, C.; Cortés, J.; Molina, C.; Urzúa, U.; Barrera, M. J.; Hermoso Ramello, Marcela; Herrera, L.; Leyton, C.; González, M. J. (Blackwell, 2015)
      ORIGINAL ARTICLEMUC1/SEC and MUC1/Y overexpression is associatedwith inflammation in Sj€ogren’s syndromeHH Sung1,*, I Castro1,*, S Gonz alez2, S Aguilera3, NI Smorodinsky4, AFG Quest1,5, V Bahamondes1,C Alliende1, J Cort ...
    • Oral dryness in Sjögren's syndrome patients. Not just a question of water 
      Castro, I.; Sepúlveda, D.; Cortés, J.; Quest, Andrew F. G.; Barrera, M. J.; Bahamondes, V.; Aguilera, S.; Urzúa, U.; Alliende, C.; Molina, C.; González, S.; Hermoso, M. A.; Leyton, C.; González, M. J. (2013)
      Sjögren's syndrome (SS) is a chronic autoimmune disease of undefined etiology. Patients with this syndrome suffer from severe alterations in both the quality and quantity of saliva and tears, due to impaired function of ...
    • Oral manifestations and their treatment in Sjögren's syndrome 
      González, S.; Sung, H.; Sepúlveda, D.; González, M.; Molina, C. (2014)
      Sjögren's syndrome (SS) is a complex, chronic, systemic, autoimmune disease that mainly affects the exocrine glands, especially the salivary and lacrimal glands, leading to dryness of the oral and ocular mucosae. Several ...
    • Reduced sulfation of MUC5B is linked to xerostomia in patients with Sjögren syndrome 
      Alliende, C.; Kwon, Y. J.; Brito, M.; Molina, C.; Aguilera, S.; Pérez, P.; Leyton, L.; Quest, Andrew F. G.; Mandel, U.; Veerman, E.; Espinosa, M.; Clausen, H.; Leyton, C.; Romo, R.; González, M. J. (2008)
      Objectives: MUC5B contains sulfated and sialylated oligosaccharides that sequester water required for moisturising the oral mucosa. Xerostomia, in patients with Sjo¨gren syndrome, is generally associated with ...
    • Severe alterations in expression and localisation of α6β4 integrin in salivary gland acini from patients ... 
      Velozo, J.; Aguilera, S.; Alliende, C.; Ewert, P.; Molina, C.; Pérez, P.; Leyton, L.; Quest, Andrew F. G.; Brito, M.; González, S.; Leyton, C.; Hermoso Ramello, Marcela; Romo, R.; González, M. J. (2009)
      Objectives: In salivary glands from patients with Sjögren syndrome, overexpression of laminins 1 and 5 and disorganisation of the acinar basal lamina have been reported. Laminin 5 mediates association of the basal lamina ...
    • Sjögren's syndrome and the epithelial target: A comprehensive review 
      Barrera, M. J.; Bahamondes, V.; Sepúlveda, D.; Quest, Andrew F. G.; Castro, I.; Cortés, J.; Aguilera, S.; Urzúa, U.; Molina, C.; Pérez, P.; Ewert, P.; Alliende, C.; Hermoso, M. A.; González, S.; Leyton, C.; González, M. J. (2013)
      The most difficult component in our understanding of human autoimmunity remains a rigorous dissection of etiological events. Indeed, the vast literature on autoimmune diseases focuses on the inflammatory response, with the ...
    • Tumor necrosis factor-α-stimulated membrane type 1-matrix metalloproteinase production is modulated by ... 
      Smith, P.C.; Guerrero, J.; Tobar, N.; Cáceres, M.; González, M. J.; Martínez, J. (2009)
      Background and Objectives: Membrane type 1-matrix metalloproteinase (MT1-MMP) is a collagenolytic enzyme involved in connective tissue remodeling. In periodontal tissues, either cytokines or growth factors regulate the ...