Browsing by Author "0e4aaa2d-186f-4ff5-8605-1abfb2126f24"

Now showing items 1-5 of 5

    • A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis 
      Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)
      The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
    • Glucocorticosteroid therapy in inflammatory bowel diseases: from clinical practice to molecular biology 
      Dubois Camacho, Karen; Ottum, Payton A.; Franco Muñoz, Daniel; Fuente, Marjorie de la; Torres Riquelme, Alejandro; Díaz Jiménez, David; Olivares Morales, Mauricio; Astudillo, Gonzalo; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Baishideng Publishing Group, 2017)
      Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are chronic pathologies associated with a deregulated immune response in the intestinal mucosa, and they are triggered by environmental ...
    • Human papillomavirus 16 E7 promotes EGFR/PI3K/AKT1/NRF2 signaling pathway contributing to PIR/NF-kappa B ... 
      Carrillo Beltrán, Diego; Muñoz, Juan P.; Guerrero Vásquez, Nahir; Blanco, Rancés; León, Oscár; de Souza Lino, Vanesca; Tapia Pineda, Julio; Maldonado Maldonado, Edio; Dubois Camacho, Karen; Hermoso Ramello, Marcela; Coravlán, Alejandro H.; Calaf, Gloria M.; Boccardo, Enrique; Aguayo González, Francisco (MDPI, 2020)
      A subset of oral carcinomas is etiologically related to high-risk human papillomavirus (HR-HPV) infection, with HPV16 being the most frequent HR-HPV type found in these carcinomas. The oncogenic role of HR-HPV is strongly ...
    • IL-33 Alarmin and its active proinflammatory fragments are released in small intestine in celiac disease 
      Pérez, Federico; Ruera, Carolina N.; Miculan, Emanuel; Carasi, Paula; Dubois Camacho, Karen; Garbi, Laura; Guzmán, Luciana; Hermoso, Marcela; Chirdo, Fernando G. (Frontiers Media, 2020)
      Initially described as Th2 promoter cytokine, more recently, IL-33 has been recognized as an alarmin, mainly in epithelial and endothelial cells. While localized in the nucleus acting as a gene regulator, it can be also ...
    • Soluble ST2 is a sensitive clinical marker of ulcerative colitis evolution 
      Díaz Jiménez, David; De la Fuente, Marjorie; Dubois Camacho, Karen; Landskron, Glauben; Fuentes, Janitza; Pérez, Tamara; González Burgos, María Julieta; Simian, Daniela; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2016)
      Background: The ST2/IL-33 pathway has been related to ulcerative colitis (UC), and soluble ST2 (sST2), to disease severity. We tested the potential usefulness of sST2 as a predictive marker of treatment response and patients' ...