Browsing by Author "1578dd96-6eae-41c4-b49b-cb27cb64128f"

Now showing items 1-6 of 6

    • Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and ... 
      Lagos, Carolina; Carvajal, Patricia; Castro, Isabel; Jara, Daniela; González, Sergio; Aguilera, Sergio; Barrera, María José; Quest, Andrew F. G.; Bahamondes, Verónica; Molina, Claudio; Urzúa, Ulises; Hermoso Ramello, Marcela; Leyton, Cecilia; González Burgos, María Julieta (Academic Press Inc., 2018)
      © 2018 Elsevier Inc.Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial ...
    • Biomarkers for screening of lung cancer and pre-neoplastic lesions in a high risk Chilean population 
      Adonis Parraguez, Marta; Díaz, Jose; Miranda, Veronica R.; Chahuan, Marco; Zambrano, Alcides; Benitez, Hugo C.; Campos, Monica; Avaria, Pablo; Urzúa, Ulises; Marín, Pedro; Gohurdett, Mariela; Cisterna, Yasna; Gil, Lionel (socbiol@huelen.reuna.cl, 2014)
      © 2014 Adonis et al. Background: The mortality of lung cancer (LC), increases each year in the world, in spite of any advances, in development of new drugs to advance stages of LC. The high incidence of LC has been associated ...
    • Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant ... 
      Urzúa, Ulises; Ampuero Llanos, Sandra; Roby, Katherine F.; Owens, Garrison A.; Munroe, David J. (BioMed Central Ltd., 2016)
      © 2016 The Author(s). Background: Based in epidemiological evidence, repetitive ovulation has been proposed to play a role in the origin of ovarian cancer by inducing an aberrant wound rupture-repair process of the ovarian ...
    • Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent ... 
      Fernández, Jaime G.; Rodríguez, Diego A.; Valenzuela, Manuel; Calderon, Claudia; Urzúa, Ulises; Munroe, David; Rosas, Carlos; Lemus, David; Díaz, Natalia; Wright, Mathew C.; Leyton Campos, Lisette; Tapia, Julio C.; Quest, Andrew F. G. (BioMed Central Ltd., 2014)
      © 2014 Fernández et al.; licensee BioMed Central Ltd.Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an ...
    • Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from ... 
      Cortés, Juan; Hidalgo, Jorge; Aguilera, Sergio; Castro, Isabel; Brito, Mónica; Urra, Hery; Pérez, Paola; Barrera, María José; Carvajal, Patricia; Urzúa, Ulises; González, Sergio; Molina, Claudio; Bahamondes, Verónica; Hermoso, Marcela; González, María Julieta (Academic Press, 2019)
      Sjögren's syndrome (SS) is an autoimmune exocrinopathy associated with severe secretory alterations by disruption of the glandular architecture integrity, which is fundamental for a correct function and localization of the ...
    • The ovarian transcriptome of reproductively aged multiparous mice: candidate genes for ovarian cancer protection 
      Urzúa, Ulises; Chacón, Carlos; Norambuena, Maximiliano; Lizama, Luis; Sarmiento, Sebastián; Asaki, Esther; Powell, John I.; Ampuero, Sandra (MDPI, 2020)
      In middle-aged women, the decline of ovarian follicle reserve below a critical threshold marks menopause, leading to hormonal, inflammatory, and metabolic changes linked to disease. The highest incidence and mortality of ...