Browsing by Author "17137e2c-03db-4b1b-8472-28a42f20ade9"
Now showing items 1-20 of 25
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Carrasco Pozo, Catalina; Gotteland, Martin; Castillo, Rodrigo L.; Chen, Chen (Academic Press Inc., 2015)© 2015 Elsevier Inc. Cholesterol plays an important role in inducing pancreatic β-cell dysfunction, characterized by an impaired insulin secretory response to glucose, representing a hallmark of the transition from ...
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Quezada, María Paz; Salinas, Carlos; Gotteland, Martin; Cardemil Oliva, Liliana (American Chemical Society, 2017)The nutraceutical properties of Aloe vera have been attributed to a glucomannan known as acemannan. Recently information has been published about the presence of fructans in Aloe vera but there are no publications about ...
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Gotteland, Martin; Magne, Fabien (American Society for Nutrition, 2017)
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Barrera Bugueno, Camila; Realini, Ornella; Escobar Luna, Jorge; Sotomayor Zarate, Ramón; Gotteland, Martin; Julio Pieper, Marcela; Bravo, Javier A. (Elsevier, 2017)Gut microbiota interventions, including probiotic and prebiotic use can alter behavior in adult animals and healthy volunteers. However, little is known about their effects in younger individuals. To investigate this, male ...
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Carrasco Pozo, Catalina; Gotteland, Martin; Speisky Cosoy, Hernán (2011)The aim of this work was to investigate the role of mitochondrial dysfunction in the development of oxidative stress and cytotoxicity induced by indomethacin and to evaluate the potential of an apple peel polyphenol extract ...
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Carrasco Pozo, Catalina; Speisky Cosoy, Hernán; Brunser, Oscar; Pastene, Edgar; Gotteland, Martin (2011)The stability of an apple peel polyphenol extract (APPE) with powerful antioxidant activity was evaluated under acidic conditions in vitro, and its protective effect against gastrointestinal damage was investigated in rats ...
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Pesoa, Susana A.; Portela, Néstor; Fernández, Eduardo; Elbarcha, Osvaldo; Gotteland, Martin; Magne, Fabien (Nature, 2021)Accumulating evidence suggests that various genetic and environmental factors contribute to the development of obesity. Among the latter, the gut microbiota has emerged as a critical player in the regulation of human ...
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Wong, Ximena; Carrasco Pozo, Catalina; Escobar, Elizabeth; Navarrete Wallace, Paola; Blachier, Francois; Andriamihaja, Mireille; Lang, Annaig; Tome, Daniel; Cires, María José; Pastene, Edgar; Gotteland, Martin (Amer Chemical Society, 2016)The protective effect of proanthocyanidin-containing polyphenol extracts from apples, avocados, cranberries, grapes, or proanthocyanidin microbial metabolites was evaluated in colonic epithelial cells exposed to p-cresol, ...
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Mao, Meng; Yu, Tao; Xiong, Ying; Wang, Zhiling; Liu, Hanmin; Gotteland, Martin; Brunser, Oscar (2008)Probiotics have been proposed for the management and prevention of acute diarrhoea in infants. A double-blind, randomised, placebo controlled study was carried out in 224 Chinese infants 6 to 36 months of age with severe ...
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Brunser, Oscar; Gotteland, Martin; Cruchet, Sylvia; Figueroa, Guillermo; Garrido, Daniel; Steenhout, Philippe (2006)Antibiotics exert deleterious effects on the intestinal microbiota, favoring the emergence of opportunistic bacteria and diarrhea. Prebiotics are nondigestible food components that stimulate the growth of bifidobacteria. ...
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Gotteland, Martin; Vizcarra, Marcela; Maury, Eduard (2010)Constipation is a complex disorder which affects an important part of the population and results in an increase of gastrointestinal symptoms and in lower stool frequency. The addition of soluble fibers (prebiotics) and ...
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Dubos, Céline; Vega, Natalia; Carvallo, Claudia; Navarrete, Paola; Cerda, Carol; Brunser, Oscar; Gotteland, Martin (2011)The biodiversity of Lactobacillus spp. in colostrum samples from 116 Chilean mothers was analyzed by PCR and 16S rDNA sequencing. Lactobacilli were isolated in 55.3% of the samples, with concentrations of 3.33 ± 0.55 (log ...
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Increase of plasma fatty acids without changes in n-6/n-3-PUFA ratio in asymptomatic obese subjects Brignardello, Jerusa; Morales, Pamela; Diaz, Erik; Brunser, Oscar; Gotteland, Martin (2011)Obesity is associated with a low grade inflammation which contributes to the development of insulin resistance and diabetes. The aim of this study was to assess the total saturated (SFAs), monounsaturated (MUFAs) and ...
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Carrasco Pozo, Catalina; Castillo, Rodrigo L.; Beltrán, Caroll; Miranda, Alfonso; Fuentes, Jocelyn; Gotteland, Martin (Elsevier Inc., 2016)© 2015 Elsevier Inc.The aim of this study was to determine the gastrointestinal protection by quercetin against indomethacin-induced oxidative stress and inflammation, with specific interest in studying the underlying ...
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Sambra Vásquez, Verónica; López Arana, Sandra; Cáceres Rodríguez, Paola; Abrigo, Karen; Collinao, Javiera; Espinoza, Alexandra; Valenzuela, Sabrina; Carvajal Gutiérrez, Bielka; Prado, Gabriel; Peralta, Rebeca; Gotteland, Martin (Frontiers Media, 2020)The prevalence of obesity among Chilean adults and children is one of the highest worldwide. To fight the constant increase of non-communicable diseases and the growing sales of sugar-sweetened beverages, the Chilean ...
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Wong, Ximena; Madrid Silva, Ana; Tralma, Karina; Castillo, Romina; Carrasco Pozo, Catalina; Navarrete Wallace, Paola; Beltrán Muñoz, Caroll; Pastene, Edgar; Gotteland, Martin (Elsevier Science, 2016-10)The intestinal absorption of bacterial lipopolysaccharide (LPS) and dietary fat has been implicated in the development of metabolic endotoxemia. This study first compared the ability of polyphenol extracts from grape, ...
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Carrasco Pozo, Catalina; Morales, Pamela; Gotteland, Martin (2013)The aim of this study was to determine the protective effect of quercetin, epigallocatechingallate, resveratrol, and rutin against the disruption of epithelial integrity induced by indomethacin in Caco-2 cell monolayers. ...
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Andriamihaja, Mireille; Lan, Annaig; Beaumont, Martin; Grauso, Marta; Gotteland, Martin; Pastene, Edgar; Cires, María José; Carrasco Pozo, Catalina; Tome, Daniel; Blachier, Francois (Springer, 2018-06)Hydrogen sulfide (H2S), a metabolic end product synthesized by the microbiota from l-cysteine, has been shown to act at low micromolar concentration as a mineral oxidative substrate in colonocytes while acting as an inhibitor ...
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Davila, Anne Marie; Blachier, François; Gotteland, Martin; Andriamihaja, Mireille; Benetti, Pierre Henri; Sanz, Yolanda; Tomé, Daniel (2013)Alimentary and endogenous proteins are mixed in the small intestinal lumen with the microbiota. Although experimental evidences suggest that the intestinal microbiota is able to incorporate and degrade some of the available ...
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Carrasco Pozo, Catalina; Tan, Kah Ni; Gotteland, Martin; Borges, Karin (Hindawi Limited, 2017)© 2017 Catalina Carrasco-Pozo et al. Cholesterol plays an important role in inducing pancreatic β-cell dysfunction, leading to an impaired insulin secretory response to glucose. This study aimed to determine the protective ...