Now showing items 1-5 of 5

    • Efficiency of pragmatic search strategies to update clinical guidelines recommendations 

      Martínez García, L.; Sanabria, A. J.; Araya Cabello, Ignacio; Lawson, J.; Solà, Iván; Vernooij, R. W. M.; López, D.; García Álvarez, E.; Trujillo Martín, M. M.; Etxeandia-Ikobaltzeta, I.; Kotzeva, A.; Rigau, D.; Louro González, A.; Barajas Nava, L.; Díaz del Campo, P.; Estrada, M. D.; Gracia, J.; Salcedo Fernández, F.; Haynes, R. B.; Alonso Coello, Pablo (BioMed Central, 2015)
      Background: A major challenge in updating clinical guidelines is to efficiently identify new, relevant evidence. We evaluated the efficiency and feasibility of two new approaches: the development of restrictive ...
    • Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide 

      Akl, Elie A; Shawwa, Khaled; Kahale, Lara A.; Agoritsas, Thomas; Brignardello Petersen, Romina; Busse, Jason W.; Carrasco Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C.; Neumann, Ignacio; Solà, Iván; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso Coello, Pablo; Guyatt, Gordon H. (BMJ Publishing Group, 2015)
      Objectives We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the ...
    • Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey 

      Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Strategies to assess the validity of recommendations: a study protocol 

      Martínez García, Laura; Sanabria, Andrea Juliana; Araya Cabello, Ignacio; Lawson, Jennifer; Haynes, R. Brian; Rigau, David; Solà, Iván; Díaz del Campo, Patra; Estrada, Maria Dolors; Etxeandia Ikobaltzeta, Itziar; García Álvarez, Elvira; Gracia, Javier; Kotzeva, Anna; Louro González, Arturo; Salcedo Fernandez, Flavia; Trujillo Martín, María Mar; Alonso Coello, Pablo (BioMed Central, 2013)
      Background: Clinical practice guidelines (CPGs) become quickly outdated and require a periodic reassessment of evidence research to maintain their validity. However, there is little research about this topic. Our project ...
    • Systematic reviews experience major limitations in reporting absolute effects 

      Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...