Now showing items 1-13 of 13

    • Comparison between the standard and a new alternative format of the Summary-of-Findings tables in Cochrane review users: study protocol for a randomized controlled trial 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per Olav; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Guyatt, Gordon H.; Schuenemann, Holger (BIOMED CENTRAL, 2015)
      Background: Systematic reviews represent one of the most important tools for knowledge translation but users often struggle with understanding and interpreting their results. GRADE Summary-of-Findings tables have been ...
    • Do clinicians want recommendations? A multicenter study comparing evidence summaries with and without GRADE recommendations 

      Neumann, Ignacio; Alonso Coello, Pablo; Vandvik, Per; Agoritsas, Thomas; Mas, Gemma; Akl, Elie; Brignardello Petersen, Romina; Emparanza, José; McCullagh, Lauren; De Sitio, Catherine; McGinn, Thomas; Almodaimegh, Hind; Almodaimegh, Khalid; Rivera, Solange; Rojas, Luis; Stirnemann, Jérôme; Irani, Jihad; Hlais, Sani; Mustafa, Reem; Bdair, Fadi; Aly, Abdelrahman; Kristiansen, Annette; Izcovich, Ariel; Ramírez Morera, Anggie; Brozek, Jan; Guyatt, Gordon H.; Schünemann, Holger (Elsevier, 2018-07)
      Objectives: Evidence-based clinical practice guidelines provide recommendations to assist clinicians in decision-making and to reduce the gap between best current research evidence and clinical practice. However, some argue ...
    • Do clinicians want recommendations? A multicenter study comparing evidence summaries with and without GRADE recommendations 

      Neumann, Ignacio; Alonso Coello, Pablo; Vandvik, Per Olav; Agoritsas, Thomas; Mas, Gemma; Akl, Elie A; Brignardello Petersen, Romina; Emparanza, Jose; McCullagh, Lauren; De Sitio, Catherine; McGinn, Thomas; Almodaimegh, Hind; Almodaimegh, Khalid; Rivera, Solange; Roja (Elsevier USA, 2018)
      © 2018 Elsevier Inc. Objectives: Evidence-based clinical practice guidelines provide recommendations to assist clinicians in decision-making and to reduce the gap between best current research evidence and clinical practice. ...
    • Efficiency of pragmatic search strategies to update clinical guidelines recommendations 

      Martínez García, L.; Sanabria, A. J.; Araya Cabello, Ignacio; Lawson, J.; Solà, Iván; Vernooij, R. W. M.; López, D.; García Álvarez, E.; Trujillo Martín, M. M.; Etxeandia-Ikobaltzeta, I.; Kotzeva, A.; Rigau, D.; Louro González, A.; Barajas Nava, L.; Díaz del Campo, P.; Estrada, M. D.; Gracia, J.; Salcedo Fernández, F.; Haynes, R. B.; Alonso Coello, Pablo (BioMed Central, 2015)
      Background: A major challenge in updating clinical guidelines is to efficiently identify new, relevant evidence. We evaluated the efficiency and feasibility of two new approaches: the development of restrictive ...
    • GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction 

      Alonso Coello, Pablo; Schunemann, Holger J.; Moberg, Jenny; Brignardello Petersen, Romina; Akl, Elie A; Davoli, Marina; Treweek, Shaun; Mustafa, Reem A.; Rada, Gabriel; Rosenbaum, Sarah; Morelli, Angela; Guyatt, Gordon H.; Oxman, Andrew D. (BMJ Publishing, 2016)
    • GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines 

      Alonso Coello, Pablo; Oxman, Andrew D.; Moberg, Jenny; Brignardello Petersen, Romina; Akl, Elie A.; Davoli, Marina; Treweek, Shaun; Mustafa, Reem A.; Vandvik, Per O.; Meerpohl, Joerg; Guyatt, Gordon H.; Schunemann, Holger J. (BMJ Publishing, 2016)
    • Guideline development process checklist 

      Etxeandia Ikobaltzeta, Itziar; Brignardello Petersen, Romina; Carrasco Labra, Alonso; Alonso Coello, Pablo (Elsevier, 2016)
    • Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format 

      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Garner, Paul; Guyatt, Gordon H.; Sch€unemann, Holger (Elsevier, 2016)
      Objectives: The current format of summary of findings (SoFs) tables for presenting effect estimates and associated quality of evidence improve understanding and assist users finding key information in systematic reviews. ...
    • Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide 

      Akl, Elie A; Shawwa, Khaled; Kahale, Lara A.; Agoritsas, Thomas; Brignardello Petersen, Romina; Busse, Jason W.; Carrasco Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C.; Neumann, Ignacio; Solà, Iván; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso Coello, Pablo; Guyatt, Gordon H. (BMJ Publishing Group, 2015)
      Objectives We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the ...
    • Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey 

      Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Strategies to assess the validity of recommendations: a study protocol 

      Martínez García, Laura; Sanabria, Andrea Juliana; Araya Cabello, Ignacio; Lawson, Jennifer; Haynes, R. Brian; Rigau, David; Solà, Iván; Díaz del Campo, Patra; Estrada, Maria Dolors; Etxeandia Ikobaltzeta, Itziar; García Álvarez, Elvira; Gracia, Javier; Kotzeva, Anna; Louro González, Arturo; Salcedo Fernandez, Flavia; Trujillo Martín, María Mar; Alonso Coello, Pablo (BioMed Central, 2013)
      Background: Clinical practice guidelines (CPGs) become quickly outdated and require a periodic reassessment of evidence research to maintain their validity. However, there is little research about this topic. Our project ...
    • Systematic reviews experience major limitations in reporting absolute effects 

      Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...
    • The GRADE evidence to decision framework: a report of its testing and application in 15 international guideline panels 

      Neumann, Ignacio; Brignardello Petersen, Romina; Wiercioch, Wojtek; Carrasco Labra, Alonso; Cuello, Carlos; Akl, Elie A.; Mustafa, Reem A.; Al-Hazzani, Waleed; Etxeandia Ikobaltzeta, Itziar; Rojas, Maria Ximena; Falavigna, Maicon; Santesso, Nancy; Brozek, Jan; Iorio, Alfonso; Alonso Coello, Pablo; Schunemann, Holger J. (BIOMED Central, 2016)
      Background: Judgments underlying guideline recommendations are seldom recorded and presented in a systematic fashion. The GRADE Evidence-to-Decision Framework (EtD) offers a transparent way to record and report guideline ...