Browsing by Author "1fbe7cfb-c0d8-46bc-bc5c-b590a397d20c"

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    • Phosphorylation of Endothelin-Converting Enzyme-1c at Serines 18 and 20 by CK2 Promotes Aggressiveness ... 
      Pérez Moreno, Pablo; Quezada Meza, Camila; Chávez Almarza, Cristopher; Niechi, Ignacio; Silva Pavez, Eduardo; Trigo Hidalgo, César; Aguayo González, Francisco; Jara Sosa, Lilian; Cáceres Verschae, Albano; Varas Godoy, Manuel; Díaz, Víctor M.; García de Herreros, Antonio; Burzio, Verónica A.; Tapia Pineda, Julio (Frontiers Media, 2020)
      Endothelin-converting enzyme-1 (ECE1) activates the endothelin-1 peptide, which upregulates pathways that are related to diverse hallmarks of cancer. ECE1 is expressed as four isoforms differing in their N-terminal domains. ...
    • SNAIL expression correlates with the translocation of syndecan-1 intracellular domain into the nucleus in ... 
      Farfán, Nancy; Orellana Serradell, Octavio; Herrera, Daniela; Chrzanowsky, Dominique; Cubillos, Paulina; Marín, Gabriel; García de Herreros, Antonio; Castellón Vera, Enrique; Contreras Muñóz, Héctor (Spandidos Publications, 2020)
      Zinc finger protein SNAI1 (SNAIL) and zinc finger protein SNAI2 (SLUG) transcription factors promote epithelial-mesenchymal transition, a process through which epithelial cells acquire a mesenchymal phenotype, increasing ...
    • The transcriptional factor ZEB1 represses Syndecan 1 expression in prostate cancer 
      Farfán, Nancy; Ocarez, Nallatt; Castellón Vera, Enrique; Mejía, Nilo; García de Herreros, Antonio; Contreras, Héctor R. (Nature, 2018)
      Syndecan 1 (SDC-1) is a cell surface proteoglycan with a significant role in cell adhesion, maintaining epithelial integrity. SDC1 expression is inversely related to aggressiveness in prostate cancer (PCa). During epithelial ...