Now showing items 1-20 of 35

    • (+ )-9C(-HYOROXYMATRINE FROM SOPHORA MACROCARPA 

      Negrete Córdova, Rosa; Cassels Niven, Bruce; Eckhardt, Gert (Pergamon Press Ltd., 1983-01-21)
      A new quinolizidine alkaloid, (+ )-9cx-hydroxymatrine, was isolated from the lea ves of Sophora macrocarpa. Its structure was determined by a combination of spectroscopic methods, among which nuclear Overhauser enhancement ...
    • Active constituents isolated from Psoralea glandulosa L. with antiinflammatory and antipyretic activities 

      Backhouse Erazo, Nadine; Delporte Vergara, Carla; Negrete Córdova, Rosa; Erazo, Silvia; Zúñiga, A.; Pinto, A.; Cassels Niven, Bruce (ELSEVIER SCI IRELAND LTD, 2001-11)
      The antiinflammatory and antipyretic activities of the petroleum ether extract (PEE), dichloromethane extract (DME) and methanol extract (ME1) of the aerial part of Psoralea glandulosa L. (Papilionaceae) were studied. The ...
    • Alcaloides de las hojas de Sophora macrocarpa 

      Negrete Córdova, Rosa; Backhouse Erazo, Nadine; Cassels Niven, Bruce (Universidad de Santiago de Chile. Dirección de Investigaciones Científicas y Tecnológicas, 1981)
      El alcaloide principal de las hojas de Sophora macrocarpa Sm. es la matrina. También fueron aisladas e identificadas N-metilcitisina y citisina, asi como N-óxido de matrina y el soforanol (5α -hidroximatrina). Los ...
    • Analgesic activity of Ugni molinae (murtilla) in mice models of acute pain 

      Delporte Vergara, Carla; Backhouse Erazo, Nadine; Inostroza, V.; Aguirre, María C.; Peredo, N.; Silva, X.; Negrete Córdova, Rosa; Miranda, Hugo (ELSEVIER IRELAND LTD, 2007-05-30)
      Leaf extracts of Ugni molinae Turcz. (Myrtaceae) are used in Chilean folk medicine as analgesic and anti-inflammatory. The antinociceptive effect of dichloromethane (I)CM), ethyl acetate (EA) and methanol (ME) leaf extracts ...
    • Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae 

      Backhouse Erazo, Nadine; Rosales, L.; Apablaza, Cecia; Goity Vivar, León Eduardo; Erazo, S.; Negrete Córdova, Rosa; Theodoluz, C.; Rodríguez, J.; Delporte Vergara, Carla (ELSEVIER IRELAND LTD, 2008-03-05)
      Abstract: Ethnopharmacological relevance: Buddleja globosa, known as "matico", is employed in Chile for wound healing. Aim of the study: To validate the traditional use of the crude drug through in vivo and in vitro ...
    • Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae 

      Backhouse Erazo, Nadine; Rosales, L.; Apablaza Escalona, Cecilia; Goity Vivar, León Eduardo; Erazo, Silvia; Negrete Córdova, Rosa; Theodoluz, C.; Rodríguez, J.; Delporte Vergara, Carla (ELSEVIER IRELAND LTD, 2008-03-05)
      Ethnopharmacological relevance: Buddleja globosa, known as "matico", is employed in Chile for wound healing. Aim of the study: To validate the traditional use of the crude drug through in vivo and in vitro evaluation of ...
    • Analgesic-antiinflammatory properties of Proustia pyrifolia 

      Delporte Vergara, Carla; Backhouse Erazo, Nadine; Erazo, Silvia; Negrete Córdova, Rosa; Vidal, P.; Silva, X.; López Pérez, J. L.; San Feliciano, Arturo; Muñoz Muñoz, Orlando (ELSEVIER IRELAND LTD, 2005-05-13)
      The anti inflammatory (per os and topic) and analgesic (per os) properties of the aerial part of Proustia pyrifolia a species in danger of extinction were investigated, and the major. compound"s of two of its active extracts ...
    • Antibacterial diterpenoids from Fabiana densa var. ramulosa 

      Erazo, Silvia; Zaldívar San Román, María Mercedes; Delporte Vergara, Carla; Backhouse Erazo, Nadine; Tapia, P.; Belmonte, E.; Delle Monache, F.; Negrete Córdova, Rosa (GEORG THIEME VERLAG KG, 2002-04)
      A biologically monitored fractionation of the resinous exudate of Fabiana densa Remy var. ramulosa Wedd. led to the isolation of the two new diterpenes: ent-beyer-15-en-18-O-succinate and ent-beyer-15-en-18-O-oxalate as ...
    • Antimicrobial activity of Psoralea glandulosa L. 

      Erazo, Silvia; González, V.; Zaldívar San Román, María Mercedes; Negrete Córdova, Rosa (SWETS ZEITLINGER PUBLISHERS, 1997-12)
      Antimicrobial activity of leaf extracts of Psoralea glandulosa L. (Papilionaceae) is reported This study was carried out on the extracts and on the plant's most abundant metabolite, bakuchiol. Antimicrobial activity against ...
    • Antinociceptive activity of Buddleja globosa (matico) in several models of pain 

      Backhouse Erazo, Nadine; Delporte Vergara, Carla; Apablaza, Cecia; Farías, Mariela; Goity Vivar, León Eduardo; Arrau, Sylvia; Negrete Córdova, Rosa; Castro, Consuelo; Miranda, Hugo (2008-09-02)
      Ethnopharmacological relevance: Leaf extracts of Buddleja globosa (Buddlejaceae) are used in Chilean folk medicine for wound healing. The anti-inflammatory (topic and per as), analgesic (per os) effects and the antioxidant ...
    • Antipyretic, hypothermic and antiinflammatory activities and metabolites from Solanum ligustrinum Lood. 

      Delporte Vergara, Carla; Backhouse Erazo, Nadine; Negrete Córdova, Rosa; Salinas, P.; Rivas Rubio, Paula Andrea; Cassels Niven, Bruce; San Feliciano, Arturo (JOHN WILEY & SONS LTD, 1998-03)
      The acute toxicities of the global methanol extract of Solanum ligustrinum (Solanaceae) and the crude steroidal glycoalkaloids mixture were determined. The antipyretic, hypothermic and antiinflammatory activities of aqueous, ...
    • Antipyretic, Hypothermic and Antiinflammatory Activities and Metabolites from Solanum ligustrinum Lood. 

      Delporte Vergara, Carla; Backhouse Erazo, Nadine; Negrete Córdova, Rosa; Salinas, P.; Rivas, P.; Cassels Niven, Bruce; San Feliciano, A. (John Wiley & Sons, Ltd., 1997-10-26)
      The acute toxicities of the global methanol extract of Solanum ligustrinum (Solanaceae) and the crude steroidal glycoalkaloids mixture were determined. The antipyretic, hypothermic and antiinflammatory activities of ...
    • Colubrinic acid isolated from a pharmacological active extract of Trevoa trinervis Miers 

      Erazo, Silvia; Backhouse Erazo, Nadine; Delporte Vergara, Carla; Negrete Córdova, Rosa; Muñoz Muñoz, Orlando; López Pérez, J. L.; San Feliciano, Arturo (Sociedad Chilena de Química, 1998)
      From Trevoa trinervis Miers (Rhammnaceae), a plant used in Chilean folklore medicine, a triterpenoid called colubrinic acid, has been isolated from a pharmacological active extract. Its structure has been established by ...
    • Constituents and biological activities from Muehlenbeckia hastulata 

      Erazo, Silvia; Muñoz Muñoz, Orlando; García, R.; Lemus Gutiérrez, Igor; Backhouse Erazo, Nadine; Negrete Córdova, Rosa; San Feliciano, Arturo; Delporte Vergara, Carla (VERLAG Z NATURFORSCH, 2002-09)
      Muehlenbeckia hastulata (J. E.Sm.) Johnst. used mainly for its abortive properties was found active for oxytoxic and analgesic activities in a biological activity screening (oxytoxic, analgesic, antimicrobial, cytotoxic ...
    • Constituents and biological activities of Schinus polygamus 

      Erazo, Silvia; Delporte Vergara, Carla; Negrete Córdova, Rosa; García, Rubén; Zaldívar San Román, María Mercedes; Iturra, Gladys; Caballero, Esther; López, José Luis; Backhouse Erazo, Nadine (ELSEVIER, 2006-10-11)
      The folk medicine employs Schinus polygamus to treat arthritic pain and cleansing of wounds. As no reports of pharmacological studies supporting its anti-inflammatory and analgesic properties, extracts of increasing polarity ...
    • Cyclobakuchiols A and B from Psoralea glandulosa 

      Backhouse Erazo, Nadine; Delporte Vergara, Carla; Negrete Córdova, Rosa; Cassels Niven, Bruce; Schneider, Christiane; Breitmaier, Eberhard; San Feliciano, Arturo (Elsevier Science ltd., 1995)
      Bioactivity guided fractionation of the dichloromethane extract from Psoralea glandulosa yielded the isolation of a diasteromeric mixture of cyclobakuchiols A and B as possible anti-inflammatory active compounds.
    • CYCLOBAKUCHIOLS A AND B FROM PSORALEA GLANDULOSA 

      Nadine Backhouse, C.; Delporte Vergara, Carla; Negrete Córdova, Rosa; Cassels Niven, Bruce; Schneider, Christiane; Breitmaier, Eberhard; San Feliciano, Arturo (Elsevier Science Ltd., 1995-01-16)
      Bioactivity guided fractionation of the dichloromethane extract from Psoralea glandulosa yielded the isolation of a diasteromeric mixture of cyc1obakuchiols A and B as possible anti-inflammatory active compounds.
    • Dehydrocostus lactone et 8 α-hydroxydehydrocostus lactone de Centaurea chilensis Hook et Arn. 

      Negrete Córdova, Rosa; Backhouse Erazo, Nadine; Avendaño, S.; San Martín, Aníbal (Cêntre d'Etude des Plantes Médicinales, 1984)
      Two sesquiterpene lactones have been isolated from the stems, leaves and flowers of Centaurea chilensis Hook. et Arn.: dehydrocostus lactone and 8 α-hydroxydehydrocostus lactone, and two steroids: β-sitosterol and stigmasterol. ...
    • Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice 

      Ferrandiz, M.; Gil, B.; Sanz, M. J.; Ubeda, A.; Erazo, Silvia; González, Ernesto; Negrete Córdova, Rosa; Pacheco, S.; Paya, M.; Alcaraz, M. J. (ROYAL PHARMACEUTICAL SOC GREAT BRITAIN, 1996-09)
      The effects of bakuchiol, a meroterpenoid isolated from the leaves of Psoralea glandulosa L., on phospholipase A(2) (PLA(2)) activity from different sources, human neutrophil responses, zymosan air pouch and topical ...
    • Estudio fitoquímico, microbiológico y farmacológico de Lophopappus Tarapacanus (PHIL.) Cabr. Asteraceae. Especie vegetal de la región altoandina. 

      Pedrasa Pizarro, Macarena Isabel (Universidad de ChileUniversidad de Chile. Programa Cybertesis, 2004)
      Lophopappus tarapacanus (Phil.) Cabr,. Asteraceae, nombre vulgar “cari, moñe y tola”, es utilizada por la medicina folclórica para dolores estomacales y lastimaduras del ganado. Es una planta que crece en la Provincia ...