Browsing by Author "201-0014881"
Now showing items 1-20 of 56
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(2Z)-3-(5-hydroxy-4-oxo-4H-chromen-3-yl)acrylonitrile
Araya Maturana, Ramiro; Heredia Moya, Jorge; Pessoa Mahana, Hernán; Weiss López, Boris; Muñoz, J. C. (BLACKWELL MUNKSGAARD, 2005-04)The title compound, C12H7NO3, consists of a chromone moiety substituted in position 3 with an acrylonitrile group in a Z configuration. The two planar groups are twisted with respect to one another. The only significant ... -
A study about regioisomeric hydroquinones with multiple intramolecular hydrogen bonding
Martínez Cifuentes, Maximiliano; Cardona, Wilson; Saitz Barría, Claudio; Weiss López, Boris; Araya Maturana, Ramiro (MDPI AG, 2017)A theoretical exploration about hydrogen bonding in a series of synthetic regioisomeric antitumor tricyclic hydroquinones is presented. The stabilization energy for the intramolecular hydrogen bond (IHB) formation in four ... -
About the difference in the quadrupole splitting of water between cationic and anionic nematic lyotropic liquid crystals. H-2-NMR and molecular dynamics study
Ahumada, H.; Montecinos, R.; Martínez, R.; Araya Maturana, Ramiro; Weiss López, Boris (SOCIEDAD CHILENA DE QUIMICA, 2004-09)Deuterium quadrupole splittings, of deuterated water, Deltav, in anionic discotic nematic lyomesophases are always much larger than in cationic mesophases. To explore the possible origins of this difference, Deltav and T-1 ... -
Assessing parameter suitability for the strength evaluation of intramolecular resonance assisted hydrogen bonding in O-carbonyl hydroquinones
Martínez Cifuentes, Maximiliano; Monroy-Cárdenas, Matías; Millas Vargas, Juan; Weiss López, Boris; Araya Maturana, Ramiro (MDPI AG, 2019)© 2019 by the authors.Intramolecular hydrogen bond (IMHB) interactions have attracted considerable attention due to their central role in molecular structure, chemical reactivity, and interactions of biologically active ... -
Average orientation and location of benzyl alcohol-d(5) and alkyl benzyl-d(5) ethers in anionic nematic lyotropic liquid crystals
Weiss López, Boris; Miño Galaz, Germán; Araya Maturana, Ramiro; Tracey, Alan S. (AMER CHEMICAL SOC, 2000-04-18)Deuterium quadrupole splittings of benzyl alcohol-d(5) and a series of alkyl benzyl-d(5), ethers, with linear aliphatic chains from 1 to 12 carbon atoms, were measured using H-2 NMR spectroscopy. These molecules were ... -
Average orientation of benzyl-d(5) alkyl ethers in cationic nematic lyomesophases
Weiss López, Boris; Saldaño Hurtado, Danilo; Araya Maturana, Ramiro; Gamboa, Consuelo (AMER CHEMICAL SOC, 1997-12-24)Deuterium quadrupole splittings from the aromatic ring of a series of linear benzyl-d(5) alkyl ethers, with alkyl chain length from 1 to 15 carbon atoms, have been measured using H-2-NMR spectroscopy. These molecules, 20% ... -
Characterisation of a new nematic lyotropic liquid crystal with natural lipids from soybean
Ruiz Fernández, Alvaro; Tejos, Ricardo; Ahumada-Gutierrez, Hernan; Muñoz-Gacitúa, Diego; Martínez Cifuentes, Maximiliano; Araya Maturana, Ramiro; Weiss López, Boris (Taylor and Francis Ltd., 2018)Searching for a lubricant to be used in articular bone joints, a new nematic liquid crystal (NLC) was characterised. It is formed by dissolving tetradecyltrimethyl ammonium bromide (TTAB), decanol (DeOH), sodium bromide ... -
Chiral discrimination of L- and D-N-acyl-1-phenyl-D-5-2-aminopropanes in a cesium N-dodecanoyl-L-threoninate cholesteric nematic lyomesophase
Ahumada, H.; Montecinos, R.; Alegría, S.; Araya Maturana, Ramiro; Weiss López, Boris (SOCIEDAD CHILENA DE QUIMICA, 2005-03)Molecular recognition based on chirality has fundamental importance in many biological processes. Deuterium quadrupole splittings from the aromatic ring and mesophase components of two series of optical isomers, L-and ... -
Composition effect on the aggregate/solution interface of a nematic lyotropic liquid crystal
Ruiz Fernández, A. R.; López Cascales, J. J.; Giner Casares, J. J.; Araya Maturana, Ramiro; Díaz Banose, F. G.; Weiss López, Boris (2016)Lyotropic nematic liquid crystals (lnlc) have attracted attention due to their resemblance to natural membranes and several technological applications. The effect of tetradecyltrimethyl ammonium chloride (TTAC) in the ... -
Conformational dynamics of substituted N-acetyl-N-phenylbenzylamines. 1H-DNMR and AM1-MO study
Weiss López, Boris; Saitz Barría, Claudio; Pessoa Mahana, Hernán; Valderrama, Jaime; Araya Maturana, Ramiro (2001)Activation parameters for the rotation around the methylene-nitrogen single bond found in a series of four 2,2'-disubstituted N-acetyl-N-phenylbenzylamines, dissolved in DMSO-d6, were measured employing the temperature ... -
Conformational dynamics of substituted N-acetyl-N-phenylbenzylamines. H-1-DNMR and AM1-MO study
Weiss López, Boris; Jullian Matthaei, Carolina; Saitz Barría, Claudio; Pessoa Mahana, Hernán; Valderrama, J.; Araya Maturana, Ramiro (SOCIEDAD CHILENA DE QUIMICA, 2001-09)Activation parameters for the rotation around the methylene-nitrogen single bond found in a series of four 2,2'-disubstituted N-acetyl-N-phenylbenzylamines, dissolved in DMSO-d(6), were measured employing the temperature ... -
Correlating experimental electrochemistry and theoretical calculations in 2 '-hydroxy chalcones: the role of the intramolecular hydrogen bond
Martínez Cifuentes, Maximiliano; Salazar, Ricardo; Escobar, Carlos A.; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Royal Soc Chemistry, 2015)In this work we present a study on the molecular structure and electrochemical behavior of a series of methoxylated 2'-hydroxychalcones, whose antitumor activity has been previously described. Cyclic voltammetry was used ... -
Counterion and composition effects on discotic nematic lyotropic liquid crystals - I. Size and order
Montecinos, R.; Ahumada, H.; Araya Maturana, Ramiro; Olea, Andrés F.; Weiss López, Boris (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2007-12-01)Counterion and composition effects on the size and interface dynamics of discotic nematic lyotropic liquid crystals made of tetradecyltrimethylammonium halide (TTAX)-decanol (DeOH)-water-NaX, with X = Cl- and Br-, were ... -
Counterion Effects and Dynamics of Parathion in Anionic Lyomesophases
Bahamonde, Víctor; Ahumada, Hernán; Araya Maturana, Ramiro; Weiss López, Boris (CSIRO PUBLISHING, 2010)Ingestion of parathion produces catastrophic effects on mammals. Transformed into paraoxon, it inhibits acetylcholinesterase, producing acetylcholine accumulation. The distribution, orientation, and dynamics of parathion ... -
Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: Bioenergetic profile and metabolic flexibility of cancer cells
Urra, Felix; Weiss López, Boris; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2016)© 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ... -
Differential incorporation of L- and D-N-acyl-1-phenyl-d(5)-2-aminopropane in a cesium N-dodecanoyl-L-alaninate cholesteric nematic lyomesophase
Weiss López, Boris; Azócar Rangel, Mauricio Alejandro; Montecinos, R.; Cassels Niven, Bruce; Araya Maturana, Ramiro (AMER CHEMICAL SOC, 2001-10-30)Deuterium quadrupole splittings from two series of optical isomers, L- and D-N-acyl-l-phenyl-d(5)-2-aminopropane, with linear acyl chains ranging from I to 10 carbon atoms, were measured using H-2 NMR spectroscopy. Both ... -
Domino inverse electron demand Diels-Alder reactions of chromones with ethyl vinyl ether
Heredia Moya, Jorge; Krohn, Karsten; Florke, Ulrich; Pessoa Mahana, Hernán; Weiss López, Boris; Estévez, A.; Araya Maturana, Ramiro (PERGAMON-ELSEVIER SCIENCE LTD, 2007-06-01)E)-Ethyl 3-(4-oxo-4H-chromen-3-yi)acrylate (3), (E)-3-(4-oxo-4H-chromen-3-yl)-2-propenenitrile (12) and their 5-hydroxy-derivatives 11 and 13 undergo alternative, solvent dependent, domino reactions with ethyl vinyl ether. ... -
Dynamics and orientation of parathion dissolved in a discotic nematic lyomesophase
Vera, Alejandra; Ahumada, Hernán; Bahamonde, Victor; Montecinos, Rodrigo; Araya Maturana, Ramiro; Muñoz, Daniel; Weiss López, Boris (CSIRO Publishing, 2008)Parathion, an organophosphorous pesticide, presents serious hazards to the environment and health. It inhibits acetylcholinesterase, an enzyme incorporated in the cell membrane. A study on the behaviour of parathion in a ... -
Effect of shape and bending modulus on the properties of nematic lyotropic liquid crystals
Ruiz Fernández, A. R.; López Cascales, J. J.; Giner Casares, J. J.; Araya Maturana, Ramiro; Díaz Banos, F. G.; Muñoz Gacitua, D.; Weiss López, Boris (The Royal Society of Chemistry, 2016)Synovial liquid is a natural lubricant of articular joints, such as shoulders, knees and hips. Thus, the development of biocompatible lubricants that can be employed in medical prosthesis for artificial implants, and ... -
Effects of 9,10-dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)- anthracenone derivatives on tumor cell respiration
Araya Maturana, Ramiro; Cardona, Wilson; Cassels Niven, Bruce; Delgado Castro, Tomás; Ferrada Parker, Jorge; Miranda, Dante; Pavani, Mario; Pessoa Mahana, Hernán; Soto Delgado, Jorge; Weiss López, Boris (Elsevier Ltd., 2006-02-28)A series of tricyclic hydroquinones, incorporating a carbonyl group in the ortho position relative to the phenol function, were tested as inhibitors of oxygen uptake against the TA3 mouse carcinoma cell line and its ...