Now showing items 1-12 of 12

    • Bugueño Valdebenito, Isaac Maximiliano (Universidad de Chile, 2014)
      La periodontitis es una enfermedad infecciosa multifactorial, caracterizada por una respuesta inflamatoria exacerbada que produce la destrucción de las estructuras que dan soporte al diente, incluyendo la encía, el ...
    • Díaz, Leonor; Hoare, Anilei; Soto, Cristopher; Bugueño, Isaac; Silva Steffens, Nora; Dutzan Muñoz, Nicolás; Venegas, Darna; Salinas, Daniela; Pérez Donoso, José; Gamonal Aravena, Jorge Antonio; Bravo Rodríguez, Denisse (Elsevier, 2015)
      Virulence factors on the surface of Porphyromonas gingivalis constitute the first line of interaction with host cells and contribute to immune modulation and periodontitis progression. In order to characterize surface ...
    • Silva Steffens, Nora; Dutzan Muñoz, Nicolás; Hernández Ríos, Emma; Dezerega Piwonka, Andrea; Rivera Escobar, Oriana; Aguillón Gutiérrez, Juan Carlos; Aravena, Octavio; Lastres, Pedro; Pozo, Patricia; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (Blackwell, 2008)
      Background and aims: Periodontitis is an infection with an episodic nature of tissue support destruction. The aim of this work was to determine the levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal ...
    • Abusleme Ramos, Loreto Andrea; O'Gorman, H.; Dutzan Muñoz, Nicolás; Greenwell-Wild, T.; Moutsopoulos, N. M. (SAGE, 2020)
      Commensal microbiomes exert critical functions at barrier sites. In particular, establishment of the commensal microbiome after birth dictates immune functionality and tissue homeostasis at mucosal surfaces. To investigate ...
    • Silva, Nora; Abusleme Ramos, Loreto Andrea; Bravo, Denisse; Dutzan Muñoz, Nicolás; García Sesnich, Jocelyn; Vernal Astudillo, Rolando; Hernández, Marcela; Gamonal Aravena, Jorge Antonio (Univ Sao Paulo Fac Odontologia Bauru, 2015)
      Periodontal diseases usually refer to common inflammatory disorders known as gingivitis and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm, including Porphyromonas gingivalis, ...
    • Dutzan Muñoz, Nicolás; Vernal Astudillo, Rolando; Hernández Ríos, Emma; Dezerega Piwonka, Andrea; Rivera Escobar, Oriana; Silva Steffens, Nora; Aguillón Gutiérrez, Juan Carlos; Puente Piccardo, Javier; Pozo, Patricia; Gamonal Aravena, Jorge Antonio (2009-02)
      Background: Periodontitis is an infection with an episodic pattern of tissue-support destruction. During the generation of a primary CD4+ T helper 1 (Th1) response, interferon-gamma (IFN-g) acts as a positive regulator ...
    • Vernal Astudillo, Rolando; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; Puente Piccardo, Javier; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (BLACKWELL MUNKSGAARD, 2005-04)
      Background and Aims: Interleukin-17 (IL-17) is a T-cell-derived cytokine that may play an important role in the initiation or maintenance of the pro-inflammatory response and has recently been found to stimulate osteoclastic ...
    • González Bergas, Fermín; Ortiz, Carolina; Reyes Rojas, Montserrat; Dutzan Muñoz, Nicolás; Patel, Vyomesh; Pereda, Cristián; Gleisner Muñoz, María Alejandra; López Nitsche, Mercedes; Gutkind, J. Silvio; Salazar Onfray, Flavio (John Wiley & Sons Ltd,, 2014)
      We have previously reported a novel method for the production of tumour-antigen-presenting cells (referred to as TAPCells) that are currently being used in cancer therapy, using an allogeneic melanomaderived cell lysate ...
    • Dezerega Piwonka, Andrea; Osorio Alfaro, Constanza; Mardones Peñailillo, Jeannette Isabel; Mundi, V.; Dutzan Muñoz, Nicolás; Franco Martínez, María Eugenia; Gamonal Aravena, Jorge Antonio; Oyarzún Droguett, Alejandro; Overall, M. C.; Hernández Ríos, Emma (John Wiley & Sons, 2010-10)
      Aim  To study the expression of monocyte chemotactic protein-3 (MCP-3, also known as chemokine CCL-7) in tissue from apical lesions (AL) and to associate MCP-3 expression with symptomatic or asymptomatic apical ...
    • Dutzan Muñoz, Nicolás (Universidad de Chile, 2003)
      La periodontitis es una enfermedad infecciosa de naturaleza inflamatoria, que involucra una respuesta inmune del hospedero y que se caracteriza por la destrucción de los tejidos de inserción del diente. Numerosos estudios ...
    • Carré, L.; Franco Martínez, María Eugenia; Henríquez, L.; García Sesnich, Jocelyn; Dutzan Muñoz, Nicolás; Aguillón Gutiérrez, Juan Carlos; Gamonal Aravena, Jorge Antonio (Sociedad de Periodoncia de Chile., 2010-12)
      La enfermedad periodontal requiere de un hospedero susceptible para su desarrollo y progresión. Dentro de las características del hospedero se encuentra la respuesta T reguladora, que otorga tolerancia frente a antígenos ...
    • Hernández Ríos, Emma; Sorsa, Timo; Obregón, Fabián; Tervahartiala, Taina; Valenzuela, María Antonieta; Pozo, Patricia; Dutzan Muñoz, Nicolás; Lesaffre, Emmanuel; Molas, Marek; Gamonal Aravena, Jorge Antonio (European Federation of Periodontology, 2009-12)
      Aim: Matrix metalloproteinases (MMP)-13 can initiate bone resorption and activate proMMP-9 in vitro, and both these MMPs have been widely implicated in tissue destruction associated with chronic periodontitis. We studied ...