Browsing by Author "20594a7a-95bb-4730-8dd3-13b414cc389b"

Now showing items 1-2 of 2

    • Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in ... 
      Cabeza, Carolina; Figueroa, Alicia; Lazo, Oscar M.; Galleguillos, Carolina; Pissani, Claudia; Klein, Andrés; González Billault, Christian; Inestrosa, Nibaldo C.; Alvarez, Alejandra R.; Zanlungo, Silvana; Bronfman, Francisca (2012)
      Background: Neurotrophins and their receptors regulate several aspects of the developing and mature nervous system, including neuronal morphology and survival. Neurotrophin receptors are active in signaling endosomes, which ...
    • Lack of activation of the unfolded protein response in mouse and cellular models of Niemann-Pick type C disease 
      Klein, Andres; Mosqueira, Matías; Martínez, Gabriela; Robledo, Fermín; González, Marcela; Caballero, Benjamín; Cancino, Gonzalo I.; Alvarez, Alejandra R.; Hetz Flores, Claudio; Zanlungo, Silvana (2011)
      Background: Niemann-Pick type C (NPC) disease is a fatal lysosomal storage disease related to progressive neurodegeneration secondary to abnormal intracellular accumulation of cholesterol. Signs of endoplasmic reticulum ...